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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1933 1
1983 1
1984 1
1989 3
1990 1
1991 2
1992 3
1993 3
1995 1
1996 4
1997 1
1998 2
2001 3
2003 2
2004 2
2005 2
2006 1
2007 4
2008 2
2009 4
2010 4
2011 6
2012 7
2013 7
2014 7
2015 2
2016 10
2017 2
2018 6
2019 2
2020 5
2021 7
2022 6
2023 6
2024 5

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113 results

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Page 1
Putting the Immunologic Brakes on Cancer.
Wolchok J. Wolchok J. Cell. 2018 Nov 29;175(6):1452-1454. doi: 10.1016/j.cell.2018.11.006. Cell. 2018. PMID: 30500529 Free article. Review.
The 2018 Nobel Prize in Medicine and Physiology has been awarded to James P. Allison and Tasuku Honjo for their discovery of cancer therapy by inhibition of negative immune regulation. These insights have given rise to a class of medicines that have now entered rout …
The 2018 Nobel Prize in Medicine and Physiology has been awarded to James P. Allison and Tasuku Honjo for their discovery of cancer t …
Rimonabant Sanofi-Synthélabo.
Fernandez JR, Allison DB. Fernandez JR, et al. Curr Opin Investig Drugs. 2004 Apr;5(4):430-5. Curr Opin Investig Drugs. 2004. PMID: 15134285 Review.
Phase III trials were initiated for obesity in August 2001 and were ongoing in September 2003. By September 2002, the compound had entered phase III trials for smoking cessation, and these trials were ongoing in September 2003....
Phase III trials were initiated for obesity in August 2001 and were ongoing in September 2003. By September 2002, the compound had entere …
Antibody and immunotherapy in diffuse large B-cell lymphoma.
Barraclough A, Hawkes EA. Barraclough A, et al. Semin Hematol. 2023 Nov;60(5):338-345. doi: 10.1053/j.seminhematol.2023.11.001. Epub 2023 Nov 23. Semin Hematol. 2023. PMID: 38072722 Review.
Since then, the advent of further "naked" monoclonal antibodies that target malignant B-cells or stimulate the immune system to kill cancer, as well as antibody-drug conjugates and bispecific antibodies have all entered the DLBCL armamentarium; with 5 antibody therapy appr …
Since then, the advent of further "naked" monoclonal antibodies that target malignant B-cells or stimulate the immune system to kill cancer, …
Obesity in pregnancy.
Davies GAL, Maxwell C, McLeod L; MATERNAL FETAL MEDICINE COMMITTEE; CLINICAL PRACTICE OBSTETRICS. Davies GAL, et al. J Obstet Gynaecol Can. 2010 Feb;32(2):165-173. doi: 10.1016/S1701-2163(16)34432-2. J Obstet Gynaecol Can. 2010. PMID: 20181319 Review.
BENEFITS, HARMS, AND COSTS: Implementation of the recommendations in this guideline should increase recognition of the issues clinicians need to be aware of when managing obese women in pregnancy, improve communication and consultation amongst the obstetrical care team, and encou …
BENEFITS, HARMS, AND COSTS: Implementation of the recommendations in this guideline should increase recognition of the issues clinicians nee …
Post-mitotic role of the cell cycle machinery.
Herrup K. Herrup K. Curr Opin Cell Biol. 2013 Dec;25(6):711-6. doi: 10.1016/j.ceb.2013.08.001. Epub 2013 Sep 18. Curr Opin Cell Biol. 2013. PMID: 24055434 Free PMC article. Review.
Although the demands placed on these cell cycle proteins are high, once cells such as neurons differentiate they enter a long non-mitotic phase where evolution has conspired to repurpose many of these proteins, leading them to assume new and often unrelated cellular tasks. …
Although the demands placed on these cell cycle proteins are high, once cells such as neurons differentiate they enter a long non-mit …
Glucocorticoids for croup in children.
Gates A, Gates M, Vandermeer B, Johnson C, Hartling L, Johnson DW, Klassen TP. Gates A, et al. Cochrane Database Syst Rev. 2018 Aug 22;8(8):CD001955. doi: 10.1002/14651858.CD001955.pub4. Cochrane Database Syst Rev. 2018. Update in: Cochrane Database Syst Rev. 2023 Jan 10;1:CD001955. doi: 10.1002/14651858.CD001955.pub5. PMID: 30133690 Free PMC article. Updated.
DATA COLLECTION AND ANALYSIS: One author extracted data from each study and another verified the extraction. We entered the data into Review Manager 5 for meta-analysis. Two review authors independently assessed risk of bias for each study using the Cochrane 'Risk of bias' …
DATA COLLECTION AND ANALYSIS: One author extracted data from each study and another verified the extraction. We entered the data into …
Lipid analogues as potential drugs for the regulation of mitochondrial cell death.
Murray M, Dyari HR, Allison SE, Rawling T. Murray M, et al. Br J Pharmacol. 2014 Apr;171(8):2051-66. doi: 10.1111/bph.12417. Br J Pharmacol. 2014. PMID: 24111728 Free PMC article. Review.
These molecules have emerged in part from an understanding of the mitochondrial actions of naturally occurring fatty acids. Some of these agents have already entered clinical trials because they specifically target known mitochondrial defects in the cancer cell....
These molecules have emerged in part from an understanding of the mitochondrial actions of naturally occurring fatty acids. Some of these ag …
Principles and use of anti-CTLA4 antibody in human cancer immunotherapy.
Peggs KS, Quezada SA, Korman AJ, Allison JP. Peggs KS, et al. Curr Opin Immunol. 2006 Apr;18(2):206-13. doi: 10.1016/j.coi.2006.01.011. Epub 2006 Feb 7. Curr Opin Immunol. 2006. PMID: 16464564 Review.
Following extensive preclinical modeling, these agents have entered clinical trials, where they are showing encouraging activity in heavily pretreated patients with advanced-stage disease, particularly with melanoma or renal carcinoma. ...
Following extensive preclinical modeling, these agents have entered clinical trials, where they are showing encouraging activity in h …
Genetic control of resistance to human malaria.
Allison AC. Allison AC. Curr Opin Immunol. 2009 Oct;21(5):499-505. doi: 10.1016/j.coi.2009.04.001. Epub 2009 May 11. Curr Opin Immunol. 2009. PMID: 19442502 Review.
A second early example of inherited innate resistance to malaria was the finding that nonexpression of the Duffy antigen/chemokine receptor (DARC) on erythrocytes confers resistance to P. vivax. However, this parasite can enter nonhuman primate red cells independently of D …
A second early example of inherited innate resistance to malaria was the finding that nonexpression of the Duffy antigen/chemokine receptor …
Clinical Development of mRNA Vaccines: Challenges and Opportunities.
August A, Brito L, Paris R, Zaks T. August A, et al. Curr Top Microbiol Immunol. 2022;440:167-186. doi: 10.1007/82_2022_259. Curr Top Microbiol Immunol. 2022. PMID: 35906319
Overall, the success of mRNA-based COVID-19 vaccines has helped unlock a platform likely to result in many more candidate vaccines entering clinical evaluation to address the unmet medical needs of other diseases including viral respiratory diseases, herpesviruses, and his …
Overall, the success of mRNA-based COVID-19 vaccines has helped unlock a platform likely to result in many more candidate vaccines enteri …
113 results