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Preclinical and Clinical Demonstration of Immunogenicity by mRNA Vaccines against H10N8 and H7N9 Influenza Viruses.
Bahl K, Senn JJ, Yuzhakov O, Bulychev A, Brito LA, Hassett KJ, Laska ME, Smith M, Almarsson Ö, Thompson J, Ribeiro AM, Watson M, Zaks T, Ciaramella G. Bahl K, et al. Among authors: almarsson o. Mol Ther. 2022 Aug 3;30(8):2874. doi: 10.1016/j.ymthe.2022.07.013. Epub 2022 Aug 2. Mol Ther. 2022. PMID: 35921837 Free PMC article. No abstract available.
Optimization of Lipid Nanoparticles for Intramuscular Administration of mRNA Vaccines.
Hassett KJ, Benenato KE, Jacquinet E, Lee A, Woods A, Yuzhakov O, Himansu S, Deterling J, Geilich BM, Ketova T, Mihai C, Lynn A, McFadyen I, Moore MJ, Senn JJ, Stanton MG, Almarsson Ö, Ciaramella G, Brito LA. Hassett KJ, et al. Among authors: almarsson o. Mol Ther Nucleic Acids. 2019 Apr 15;15:1-11. doi: 10.1016/j.omtn.2019.01.013. Epub 2019 Feb 7. Mol Ther Nucleic Acids. 2019. PMID: 30785039 Free PMC article.
mRNA vaccines against H10N8 and H7N9 influenza viruses of pandemic potential are immunogenic and well tolerated in healthy adults in phase 1 randomized clinical trials.
Feldman RA, Fuhr R, Smolenov I, Mick Ribeiro A, Panther L, Watson M, Senn JJ, Smith M, Almarsson Ӧ, Pujar HS, Laska ME, Thompson J, Zaks T, Ciaramella G. Feldman RA, et al. Vaccine. 2019 May 31;37(25):3326-3334. doi: 10.1016/j.vaccine.2019.04.074. Epub 2019 May 10. Vaccine. 2019. PMID: 31079849 Free article. Clinical Trial.
Impact of lipid nanoparticle size on mRNA vaccine immunogenicity.
Hassett KJ, Higgins J, Woods A, Levy B, Xia Y, Hsiao CJ, Acosta E, Almarsson Ö, Moore MJ, Brito LA. Hassett KJ, et al. Among authors: almarsson o. J Control Release. 2021 Jul 10;335:237-246. doi: 10.1016/j.jconrel.2021.05.021. Epub 2021 May 18. J Control Release. 2021. PMID: 34019945 Free article.
A Novel Amino Lipid Series for mRNA Delivery: Improved Endosomal Escape and Sustained Pharmacology and Safety in Non-human Primates.
Sabnis S, Kumarasinghe ES, Salerno T, Mihai C, Ketova T, Senn JJ, Lynn A, Bulychev A, McFadyen I, Chan J, Almarsson Ö, Stanton MG, Benenato KE. Sabnis S, et al. Among authors: almarsson o. Mol Ther. 2018 Jun 6;26(6):1509-1519. doi: 10.1016/j.ymthe.2018.03.010. Epub 2018 Mar 14. Mol Ther. 2018. PMID: 29653760 Free PMC article.
Boosting Intracellular Delivery of Lipid Nanoparticle-Encapsulated mRNA.
Patel S, Ashwanikumar N, Robinson E, DuRoss A, Sun C, Murphy-Benenato KE, Mihai C, Almarsson Ö, Sahay G. Patel S, et al. Among authors: almarsson o. Nano Lett. 2017 Sep 13;17(9):5711-5718. doi: 10.1021/acs.nanolett.7b02664. Epub 2017 Aug 24. Nano Lett. 2017. PMID: 28836442 Free PMC article.
Author Correction: Naturally-occurring cholesterol analogues in lipid nanoparticles induce polymorphic shape and enhance intracellular delivery of mRNA.
Patel S, Ashwanikumar N, Robinson E, Xia Y, Mihai C, Griffith JP 3rd, Hou S, Esposito AA, Ketova T, Welsher K, Joyal JL, Almarsson Ö, Sahay G. Patel S, et al. Among authors: almarsson o. Nat Commun. 2020 Jul 6;11(1):3435. doi: 10.1038/s41467-020-17025-7. Nat Commun. 2020. PMID: 32632117 Free PMC article.
41 results