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Year Number of Results
1982 1
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1996 2
1997 2
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2003 1
2004 1
2005 2
2008 2
2009 2
2011 2
2012 5
2013 2
2014 5
2015 1
2016 4
2017 6
2018 4
2019 2
2020 4
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2023 2
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55 results

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Page 1
Efficacy and Safety of NVX-CoV2373 in Adults in the United States and Mexico.
Dunkle LM, Kotloff KL, Gay CL, Áñez G, Adelglass JM, Barrat Hernández AQ, Harper WL, Duncanson DM, McArthur MA, Florescu DF, McClelland RS, Garcia-Fragoso V, Riesenberg RA, Musante DB, Fried DL, Safirstein BE, McKenzie M, Jeanfreau RJ, Kingsley JK, Henderson JA, Lane DC, Ruíz-Palacios GM, Corey L, Neuzil KM, Coombs RW, Greninger AL, Hutter J, Ake JA, Smith K, Woo W, Cho I, Glenn GM, Dubovsky F; 2019nCoV-301 Study Group. Dunkle LM, et al. N Engl J Med. 2022 Feb 10;386(6):531-543. doi: 10.1056/NEJMoa2116185. Epub 2021 Dec 15. N Engl J Med. 2022. PMID: 34910859 Free PMC article. Clinical Trial.
Most sequenced viral genomes (48 of 61, 79%) were variants of concern or interest - largely B.1.1.7 (alpha) (31 of the 35 genomes for variants of concern, 89%). Vaccine efficacy against any variant of concern or interest was 92.6% (95% CI, 83.6 to 96.7). ...
Most sequenced viral genomes (48 of 61, 79%) were variants of concern or interest - largely B.1.1.7 (alpha) (31 of the 35 genomes for …
Triglyceride Lowering with Pemafibrate to Reduce Cardiovascular Risk.
Das Pradhan A, Glynn RJ, Fruchart JC, MacFadyen JG, Zaharris ES, Everett BM, Campbell SE, Oshima R, Amarenco P, Blom DJ, Brinton EA, Eckel RH, Elam MB, Felicio JS, Ginsberg HN, Goudev A, Ishibashi S, Joseph J, Kodama T, Koenig W, Leiter LA, Lorenzatti AJ, Mankovsky B, Marx N, Nordestgaard BG, Páll D, Ray KK, Santos RD, Soran H, Susekov A, Tendera M, Yokote K, Paynter NP, Buring JE, Libby P, Ridker PM; PROMINENT Investigators. Das Pradhan A, et al. N Engl J Med. 2022 Nov 24;387(21):1923-1934. doi: 10.1056/NEJMoa2210645. Epub 2022 Nov 5. N Engl J Med. 2022. PMID: 36342113 Clinical Trial.
Pemafibrate, a selective peroxisome proliferator-activated receptor alpha modulator, reduces triglyceride levels and improves other lipid levels. ...
Pemafibrate, a selective peroxisome proliferator-activated receptor alpha modulator, reduces triglyceride levels and improves other l …
The effect of alpha-cyclodextrin on postprandial lipid and glycemic responses to a fat-containing meal.
Jarosz PA, Fletcher E, Elserafy E, Artiss JD, Jen KL. Jarosz PA, et al. Metabolism. 2013 Oct;62(10):1443-7. doi: 10.1016/j.metabol.2013.05.015. Epub 2013 Jun 24. Metabolism. 2013. PMID: 23806736 Clinical Trial.
OBJECTIVE: alpha-Cyclodextrin (alpha-CD), a soluble dietary fiber derived from corn, marketed under the trade name FBCx, has the potential to help individuals manage their weight and improve their lipid profiles. ...Furthermore, alpha-CD use was associated wi …
OBJECTIVE: alpha-Cyclodextrin (alpha-CD), a soluble dietary fiber derived from corn, marketed under the trade name FBCx, has t …
Molluscan immune defenses.
Gliński Z, Jarosz J. Gliński Z, et al. Arch Immunol Ther Exp (Warsz). 1997;45(2-3):149-55. Arch Immunol Ther Exp (Warsz). 1997. PMID: 9597080 Review.
Up to now the role of mercenenes, paolins, acute phase reactants, alpha 2-macroglobulins and multifunctional binding proteins with anti-protease activity is not well clarified yet. ...
Up to now the role of mercenenes, paolins, acute phase reactants, alpha 2-macroglobulins and multifunctional binding proteins with an …
Antioxidant and anti-inflammatory effects of zinc. Zinc-dependent NF-κB signaling.
Jarosz M, Olbert M, Wyszogrodzka G, Młyniec K, Librowski T. Jarosz M, et al. Inflammopharmacology. 2017 Feb;25(1):11-24. doi: 10.1007/s10787-017-0309-4. Epub 2017 Jan 12. Inflammopharmacology. 2017. PMID: 28083748 Free PMC article. Review.
In vitro studies have shown that zinc decreases NF-kappaB activation and its target genes, such as TNF-alpha and IL-1beta, and increases the gene expression of A20 and PPAR-alpha, the two zinc finger proteins with anti-inflammatory properties. ...
In vitro studies have shown that zinc decreases NF-kappaB activation and its target genes, such as TNF-alpha and IL-1beta, and increa …
The presence and clinical implications of alpha-2,6-galactose-linked sialic acids in non-small-cell lung cancer brain metastases--preliminary study.
Pelak MJ, Jarosz B, Straczynska-Niemiec A, Krawczyk P, Skoczylas P, Pecka KM, Snietura M, Szumilo J, Trojanowski T. Pelak MJ, et al. Folia Histochem Cytobiol. 2014;52(2):104-11. doi: 10.5603/FHC.2014.0012. Folia Histochem Cytobiol. 2014. PMID: 25007178 Free article.
Identifying biomarkers which specifically identify patients at high risk of BM may improve their early diagnosis, which is crucial for surgical and radiotherapeutic treatment outcome. Alpha-2,6-sialyltransferase (alpha-2,6-ST) and the primary product of its activity …
Identifying biomarkers which specifically identify patients at high risk of BM may improve their early diagnosis, which is crucial for surgi …
Plant Elongator-Protein Complex of Diverse Activities Regulates Growth, Development, and Immune Responses.
Jarosz M, Van Lijsebettens M, Woloszynska M. Jarosz M, et al. Int J Mol Sci. 2020 Sep 22;21(18):6912. doi: 10.3390/ijms21186912. Int J Mol Sci. 2020. PMID: 32971769 Free PMC article. Review.
Plant Elongator was also implicated in other processes: transcription and processing of miRNA, regulation of DNA replication by histone acetylation, and acetylation of alpha-tubulin. Moreover, tRNA modification, discovered first in yeast and confirmed in plants, was claime …
Plant Elongator was also implicated in other processes: transcription and processing of miRNA, regulation of DNA replication by histone acet …
The Molecular Influence of Graphene and Graphene Oxide on the Immune System Under In Vitro and In Vivo Conditions.
Dudek I, Skoda M, Jarosz A, Szukiewicz D. Dudek I, et al. Arch Immunol Ther Exp (Warsz). 2016 Jun;64(3):195-215. doi: 10.1007/s00005-015-0369-3. Epub 2015 Oct 26. Arch Immunol Ther Exp (Warsz). 2016. PMID: 26502273 Free article. Review.
Under in vitro conditions graphene and GO cause an increased production of pro-inflammatory cytokines, mainly IL-1, IL-6, IL-10 and TNF-alpha, as a result of the activation of Toll-like receptors in macrophages. ...
Under in vitro conditions graphene and GO cause an increased production of pro-inflammatory cytokines, mainly IL-1, IL-6, IL-10 and TNF-a
Emergence of constitutively active estrogen receptor-alpha mutations in pretreated advanced estrogen receptor-positive breast cancer.
Jeselsohn R, Yelensky R, Buchwalter G, Frampton G, Meric-Bernstam F, Gonzalez-Angulo AM, Ferrer-Lozano J, Perez-Fidalgo JA, Cristofanilli M, Gómez H, Arteaga CL, Giltnane J, Balko JM, Cronin MT, Jarosz M, Sun J, Hawryluk M, Lipson D, Otto G, Ross JS, Dvir A, Soussan-Gutman L, Wolf I, Rubinek T, Gilmore L, Schnitt S, Come SE, Pusztai L, Stephens P, Brown M, Miller VA. Jeselsohn R, et al. Clin Cancer Res. 2014 Apr 1;20(7):1757-1767. doi: 10.1158/1078-0432.CCR-13-2332. Epub 2014 Jan 7. Clin Cancer Res. 2014. PMID: 24398047 Free PMC article.
PURPOSE: We undertook this study to determine the prevalence of estrogen receptor (ER) alpha (ESR1) mutations throughout the natural history of hormone-dependent breast cancer and to delineate the functional roles of the most commonly detected alterations. ...
PURPOSE: We undertook this study to determine the prevalence of estrogen receptor (ER) alpha (ESR1) mutations throughout the natural …
55 results