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Preclinical Evaluation of Foamy Virus Vector-Mediated Gene Addition in Human Hematopoietic Stem/Progenitor Cells for Correction of Leukocyte Adhesion Deficiency Type 1.
Smith RH, Bloomer H, Fink D, Keyvanfar K, Nasimuzzaman M, Sancheznieto F, Dutta R, Guenther Bui K, Alvarado LJ, Bauer TR Jr, Hickstein DD, Russell DW, Malik P, van der Loo JCM, Highfill SL, Kuhns DB, Pirooznia M, Larochelle A. Smith RH, et al. Among authors: alvarado lj. Hum Gene Ther. 2022 Dec;33(23-24):1293-1304. doi: 10.1089/hum.2022.065. Epub 2022 Nov 1. Hum Gene Ther. 2022. PMID: 36094106 Free PMC article.
Eltrombopag promotes DNA repair in human hematopoietic stem and progenitor cells.
Guenther KL, Cheruku PS, Cash A, Smith RH, Alvarado LJ, Burkett S, Townsley DM, Winkler T, Larochelle A. Guenther KL, et al. Among authors: alvarado lj. Exp Hematol. 2019 May;73:1-6.e6. doi: 10.1016/j.exphem.2019.03.002. Epub 2019 Apr 13. Exp Hematol. 2019. PMID: 30986494 Free PMC article.
Commensal microbiota drive the functional diversification of colon macrophages.
Kang B, Alvarado LJ, Kim T, Lehmann ML, Cho H, He J, Li P, Kim BH, Larochelle A, Kelsall BL. Kang B, et al. Among authors: alvarado lj. Mucosal Immunol. 2020 Mar;13(2):216-229. doi: 10.1038/s41385-019-0228-3. Epub 2019 Nov 26. Mucosal Immunol. 2020. PMID: 31772323 Free PMC article.
Combinatorial single-cell CRISPR screens by direct guide RNA capture and targeted sequencing.
Replogle JM, Norman TM, Xu A, Hussmann JA, Chen J, Cogan JZ, Meer EJ, Terry JM, Riordan DP, Srinivas N, Fiddes IT, Arthur JG, Alvarado LJ, Pfeiffer KA, Mikkelsen TS, Weissman JS, Adamson B. Replogle JM, et al. Among authors: alvarado lj. Nat Biotechnol. 2020 Aug;38(8):954-961. doi: 10.1038/s41587-020-0470-y. Epub 2020 Mar 30. Nat Biotechnol. 2020. PMID: 32231336 Free PMC article.
Polypill with or without Aspirin in Persons without Cardiovascular Disease.
Yusuf S, Joseph P, Dans A, Gao P, Teo K, Xavier D, López-Jaramillo P, Yusoff K, Santoso A, Gamra H, Talukder S, Christou C, Girish P, Yeates K, Xavier F, Dagenais G, Rocha C, McCready T, Tyrwhitt J, Bosch J, Pais P; International Polycap Study 3 Investigators. Yusuf S, et al. N Engl J Med. 2021 Jan 21;384(3):216-228. doi: 10.1056/NEJMoa2028220. Epub 2020 Nov 13. N Engl J Med. 2021. PMID: 33186492 Free PMC article. Clinical Trial.
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