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Dual targeting of HER3 and MEK may overcome HER3-dependent drug-resistance of colon cancers.
Bon G, Loria R, Amoreo CA, Verdina A, Sperduti I, Mastrofrancesco A, Soddu S, Diodoro MG, Mottolese M, Todaro M, Stassi G, Milella M, De Maria R, Falcioni R. Bon G, et al. Among authors: amoreo ca. Oncotarget. 2016 Aug 19;8(65):108463-108479. doi: 10.18632/oncotarget.11400. eCollection 2017 Dec 12. Oncotarget. 2016. PMID: 29312543 Free PMC article.
Cancer stem cells: are they responsible for treatment failure?
Maugeri-Saccà M, Vici P, Di Lauro L, Barba M, Amoreo CA, Gallo E, Mottolese M, De Maria R. Maugeri-Saccà M, et al. Among authors: amoreo ca. Future Oncol. 2014 Oct;10(13):2033-44. doi: 10.2217/fon.14.126. Future Oncol. 2014. PMID: 25396775 Review.
Cancer Stem Cell-Based Models of Colorectal Cancer Reveal Molecular Determinants of Therapy Resistance.
De Angelis ML, Zeuner A, Policicchio E, Russo G, Bruselles A, Signore M, Vitale S, De Luca G, Pilozzi E, Boe A, Stassi G, Ricci-Vitiani L, Amoreo CA, Pagliuca A, Francescangeli F, Tartaglia M, De Maria R, Baiocchi M. De Angelis ML, et al. Among authors: amoreo ca. Stem Cells Transl Med. 2016 Apr;5(4):511-23. doi: 10.5966/sctm.2015-0214. Epub 2016 Mar 8. Stem Cells Transl Med. 2016. PMID: 26956206 Free PMC article.
Computational drugs repositioning identifies inhibitors of oncogenic PI3K/AKT/P70S6K-dependent pathways among FDA-approved compounds.
Carrella D, Manni I, Tumaini B, Dattilo R, Papaccio F, Mutarelli M, Sirci F, Amoreo CA, Mottolese M, Iezzi M, Ciolli L, Aria V, Bosotti R, Isacchi A, Loreni F, Bardelli A, Avvedimento VE, di Bernardo D, Cardone L. Carrella D, et al. Among authors: amoreo ca. Oncotarget. 2016 Sep 13;7(37):58743-58758. doi: 10.18632/oncotarget.11318. Oncotarget. 2016. PMID: 27542212 Free PMC article.
SIRT6 interacts with TRF2 and promotes its degradation in response to DNA damage.
Rizzo A, Iachettini S, Salvati E, Zizza P, Maresca C, D'Angelo C, Benarroch-Popivker D, Capolupo A, Del Gaudio F, Cosconati S, Di Maro S, Merlino F, Novellino E, Amoreo CA, Mottolese M, Sperduti I, Gilson E, Biroccio A. Rizzo A, et al. Among authors: amoreo ca. Nucleic Acids Res. 2017 Feb 28;45(4):1820-1834. doi: 10.1093/nar/gkw1202. Nucleic Acids Res. 2017. PMID: 27923994 Free PMC article.
DNA damage repair and survival outcomes in advanced gastric cancer patients treated with first-line chemotherapy.
Ronchetti L, Melucci E, De Nicola F, Goeman F, Casini B, Sperati F, Pallocca M, Terrenato I, Pizzuti L, Vici P, Sergi D, Di Lauro L, Amoreo CA, Gallo E, Diodoro MG, Pescarmona E, Vitale I, Barba M, Buglioni S, Mottolese M, Fanciulli M, De Maria R, Maugeri-Saccà M. Ronchetti L, et al. Among authors: amoreo ca. Int J Cancer. 2017 Jun 1;140(11):2587-2595. doi: 10.1002/ijc.30668. Epub 2017 Mar 11. Int J Cancer. 2017. PMID: 28233295 Free article.
CHK1-targeted therapy to deplete DNA replication-stressed, p53-deficient, hyperdiploid colorectal cancer stem cells.
Manic G, Signore M, Sistigu A, Russo G, Corradi F, Siteni S, Musella M, Vitale S, De Angelis ML, Pallocca M, Amoreo CA, Sperati F, Di Franco S, Barresi S, Policicchio E, De Luca G, De Nicola F, Mottolese M, Zeuner A, Fanciulli M, Stassi G, Maugeri-Saccà M, Baiocchi M, Tartaglia M, Vitale I, De Maria R. Manic G, et al. Among authors: amoreo ca. Gut. 2018 May;67(5):903-917. doi: 10.1136/gutjnl-2016-312623. Epub 2017 Apr 7. Gut. 2018. PMID: 28389531 Free PMC article.
Expression of the Hippo transducer TAZ in association with WNT pathway mutations impacts survival outcomes in advanced gastric cancer patients treated with first-line chemotherapy.
Melucci E, Casini B, Ronchetti L, Pizzuti L, Sperati F, Pallocca M, De Nicola F, Goeman F, Gallo E, Amoreo CA, Sergi D, Terrenato I, Vici P, Di Lauro L, Diodoro MG, Pescarmona E, Barba M, Mazzotta M, Mottolese M, Fanciulli M, Ciliberto G, De Maria R, Buglioni S, Maugeri-Saccà M. Melucci E, et al. Among authors: amoreo ca. J Transl Med. 2018 Feb 5;16(1):22. doi: 10.1186/s12967-018-1385-y. J Transl Med. 2018. PMID: 29402328 Free PMC article.
32 results