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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1959 1
1963 5
1964 8
1965 1
1972 1
1975 2
1976 2
1977 3
1978 4
1979 5
1980 11
1981 7
1982 9
1983 8
1984 11
1985 11
1986 20
1987 10
1988 17
1989 18
1990 19
1991 30
1992 24
1993 23
1994 25
1995 23
1996 27
1997 32
1998 26
1999 38
2000 39
2001 28
2002 41
2003 44
2004 50
2005 56
2006 60
2007 77
2008 68
2009 55
2010 60
2011 65
2012 67
2013 74
2014 65
2015 77
2016 47
2017 48
2018 57
2019 62
2020 49
2021 48
2022 47
2023 46
2024 19

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1,556 results

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Page 1
AMPH-1 As A Critical Tumor Suppressor That Inhibits Osteosarcoma Progression.
Zhang H, Liu Y, Xu K, Mao K, Han W, Xu F, Wan W, Sun Y. Zhang H, et al. Cancer Manag Res. 2019 Nov 25;11:9913-9919. doi: 10.2147/CMAR.S220544. eCollection 2019. Cancer Manag Res. 2019. PMID: 31819629 Free PMC article.
Notably, silencing AMPH-1 increased osteosarcoma progression in a mouse tumor model. The results obtained upon AMPH-1 knockdown and AMPH-1 overexpression indicates that AMPH-1 is involved in regulating MEK/ERK signaling. ...
Notably, silencing AMPH-1 increased osteosarcoma progression in a mouse tumor model. The results obtained upon AMPH-1 knockdow …
AMPH-1 is critical for breast cancer progression.
Chen Y, Liu J, Li L, Xia H, Lin Z, Zhong T. Chen Y, et al. J Cancer. 2018 May 25;9(12):2175-2182. doi: 10.7150/jca.25428. eCollection 2018. J Cancer. 2018. PMID: 29937937 Free PMC article.
Of note, knockdown of AMPH-1 promotes breast cancer progression in xenograft mouse model. ...In summary, our results identified the anti-oncogenic function of AMPH-1 in breast cancer in vitro and in vivo. Activation of AMPH-1 may be a promising approach to tr …
Of note, knockdown of AMPH-1 promotes breast cancer progression in xenograft mouse model. ...In summary, our results identified the a …
AMPH-1 is a tumor suppressor of lung cancer by inhibiting Ras-Raf-MEK-ERK signal pathway.
Yang H, Wan Z, Huang C, Yin H, Song D. Yang H, et al. Lasers Med Sci. 2019 Apr;34(3):473-478. doi: 10.1007/s10103-018-2616-4. Epub 2018 Aug 24. Lasers Med Sci. 2019. PMID: 30143925
In vivo xenograft studies confirmed that the AMPH-1-knockdown cells were more tumorigenic than the controls. Moreover, we demonstrated that silencing AMPH-1 markedly activated Ras-Raf-MEK-ERK signal pathway. In summary, our results identified the anti-oncogenic func …
In vivo xenograft studies confirmed that the AMPH-1-knockdown cells were more tumorigenic than the controls. Moreover, we demonstrate …
Pharmacological Treatment of Methamphetamine/Amphetamine Dependence: A Systematic Review.
Siefried KJ, Acheson LS, Lintzeris N, Ezard N. Siefried KJ, et al. CNS Drugs. 2020 Apr;34(4):337-365. doi: 10.1007/s40263-020-00711-x. CNS Drugs. 2020. PMID: 32185696 Free PMC article.
BACKGROUND: Stimulant drugs are second only to cannabis as the most widely used class of illicit drug globally, accounting for 68 million past-year consumers. Dependence on amphetamines (AMPH) or methamphetamine (MA) is a growing global concern. Yet, there is no establishe …
BACKGROUND: Stimulant drugs are second only to cannabis as the most widely used class of illicit drug globally, accounting for 68 million pa …
GTP-stimulated membrane fission by the N-BAR protein AMPH-1.
Kustigian L, Gong X, Gai W, Thongchol J, Zhang J, Puchalla J, Carr CM, Rye HS. Kustigian L, et al. Traffic. 2023 Jan;24(1):34-47. doi: 10.1111/tra.12875. Epub 2022 Dec 13. Traffic. 2023. PMID: 36435193 Free PMC article.
In Caenorhabditis elegans, formation of transport carriers from the recycling endosome requires the dynamin-like, Eps15-homology domain (EHD) protein, RME-1, functioning with the Bin/Amphiphysin/Rvs (N-BAR) domain protein, AMPH-1. Here we show, using a free-solution single …
In Caenorhabditis elegans, formation of transport carriers from the recycling endosome requires the dynamin-like, Eps15-homology domain (EHD …
AmpH, a bifunctional DD-endopeptidase and DD-carboxypeptidase of Escherichia coli.
González-Leiza SM, de Pedro MA, Ayala JA. González-Leiza SM, et al. J Bacteriol. 2011 Dec;193(24):6887-94. doi: 10.1128/JB.05764-11. Epub 2011 Oct 14. J Bacteriol. 2011. PMID: 22001512 Free PMC article.
The N-terminal export signal of AmpH is processed, but the protein remains membrane associated. The PBP nature of AmpH was demonstrated by its ability to bind the beta-lactams Bocillin FL (a fluorescent penicillin) and cefmetazole. In vitro assays with AmpH a …
The N-terminal export signal of AmpH is processed, but the protein remains membrane associated. The PBP nature of AmpH was dem …
Impact of two different types of exercise training on AMPH addiction: Role of hippocampal neurotrophins.
Segat HJ, Martini F, Roversi K, Rosa SG, Muller SG, Rossato DR, Nogueira CW, Burger ME. Segat HJ, et al. Physiol Behav. 2022 Jul 1;251:113804. doi: 10.1016/j.physbeh.2022.113804. Epub 2022 Apr 8. Physiol Behav. 2022. PMID: 35398334
INTRODUCTION: Amphetamine (AMPH) abuse results in neurobehavioral alterations related to the reward circuit. ...OBJECTIVE: This study aimed to compare the effects of non-weight-loaded and weight-loaded physical exercise on behavioral (relapse, memory and anxiety) and hippo …
INTRODUCTION: Amphetamine (AMPH) abuse results in neurobehavioral alterations related to the reward circuit. ...OBJECTIVE: This study …
miR-425 regulates cell proliferation, migration and apoptosis by targeting AMPH-1 in non-small-cell lung cancer.
Jiang L, Ge W, Geng J. Jiang L, et al. Pathol Res Pract. 2019 Dec;215(12):152705. doi: 10.1016/j.prp.2019.152705. Epub 2019 Oct 23. Pathol Res Pract. 2019. PMID: 31685299
Moreover, we proved that miR-425 could target AMPH-1. The expression of AMPH-1was upregulated in A549 with miR-425 inhibitor. ...CONCLUSIONS: Taken together, miR-425 could promote the proliferation, invasion and suppress apoptosis by targeting AMPH-1 in NSCLC …
Moreover, we proved that miR-425 could target AMPH-1. The expression of AMPH-1was upregulated in A549 with miR-425 inhibitor. …
AmpC and AmpH, proteins related to the class C beta-lactamases, bind penicillin and contribute to the normal morphology of Escherichia coli.
Henderson TA, Young KD, Denome SA, Elf PK. Henderson TA, et al. J Bacteriol. 1997 Oct;179(19):6112-21. doi: 10.1128/jb.179.19.6112-6121.1997. J Bacteriol. 1997. PMID: 9324260 Free PMC article.
Although closely related to AmpC and other class C beta-lactamases, AmpH showed no beta-lactamase activity toward the substrate nitrocefin. Mutation of the ampC and/or ampH genes in E. coli lacking PBPs 1a and 5 produced morphologically aberrant cells, particularly …
Although closely related to AmpC and other class C beta-lactamases, AmpH showed no beta-lactamase activity toward the substrate nitro …
Amphetamine extended-release oral suspension for attention-deficit/hyperactivity disorder.
Childress AC, Chow H. Childress AC, et al. Expert Rev Clin Pharmacol. 2019 Oct;12(10):965-971. doi: 10.1080/17512433.2019.1659723. Epub 2019 Sep 16. Expert Rev Clin Pharmacol. 2019. PMID: 31526076 Review.
AMPH extended-release oral suspension, Dyanavel XR, (AMPH EROS) was developed to address the unmet needs of patients who have difficulty swallowing intact extended-release (ER) tablets and capsules. ...Efficacy data from two clinical trials are presented and AMPH …
AMPH extended-release oral suspension, Dyanavel XR, (AMPH EROS) was developed to address the unmet needs of patients who have …
1,556 results