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1969 6
1970 7
1971 9
1972 14
1973 11
1974 14
1975 43
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1977 45
1978 45
1979 57
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1981 72
1982 89
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1984 113
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1986 113
1987 115
1988 120
1989 165
1990 193
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1992 235
1993 566
1994 566
1995 292
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1997 385
1998 377
1999 372
2000 437
2001 433
2002 358
2003 333
2004 304
2005 304
2006 310
2007 292
2008 299
2009 313
2010 331
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2012 407
2013 422
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2024 126

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Page 1
Showing results for atp carrier
Search for Amy Carriker instead (1 results)
The Molecular Mechanism of Transport by the Mitochondrial ADP/ATP Carrier.
Ruprecht JJ, King MS, Zögg T, Aleksandrova AA, Pardon E, Crichton PG, Steyaert J, Kunji ERS. Ruprecht JJ, et al. Cell. 2019 Jan 24;176(3):435-447.e15. doi: 10.1016/j.cell.2018.11.025. Epub 2019 Jan 2. Cell. 2019. PMID: 30611538 Free PMC article.
Mitochondrial ADP/ATP carriers transport ADP into the mitochondrial matrix for ATP synthesis, and ATP out to fuel the cell, by cycling between cytoplasmic-open and matrix-open states. ...Here, we describe the structure of the matrix-open state l …
Mitochondrial ADP/ATP carriers transport ADP into the mitochondrial matrix for ATP synthesis, and ATP out to fue …
Mitochondrial ADP/ATP Carrier 1 Is Important for the Growth of Toxoplasma Tachyzoites.
Qian J, Zhao T, Guo L, Li S, He Z, He M, Shen B, Fang R. Qian J, et al. Microbiol Spectr. 2023 Jun 15;11(3):e0004023. doi: 10.1128/spectrum.00040-23. Epub 2023 May 8. Microbiol Spectr. 2023. PMID: 37154708 Free PMC article.
During this process, transporters that move metabolites across organelle membranes play pivotal roles. The highly conserved ADP/ATP carrier (AAC) involved in ATP and ADP exchange between the mitochondria and cytoplasm is key to linking the metabolic activitie …
During this process, transporters that move metabolites across organelle membranes play pivotal roles. The highly conserved ADP/ATP …
The transport mechanism of the mitochondrial ADP/ATP carrier.
Kunji ER, Aleksandrova A, King MS, Majd H, Ashton VL, Cerson E, Springett R, Kibalchenko M, Tavoulari S, Crichton PG, Ruprecht JJ. Kunji ER, et al. Biochim Biophys Acta. 2016 Oct;1863(10):2379-93. doi: 10.1016/j.bbamcr.2016.03.015. Epub 2016 Mar 19. Biochim Biophys Acta. 2016. PMID: 27001633 Free article. Review.
The mitochondrial ADP/ATP carrier imports ADP from the cytosol and exports ATP from the mitochondrial matrix, which are key transport steps for oxidative phosphorylation in eukaryotic organisms. ...The transporter cycles between a cytoplasmic and matrix st …
The mitochondrial ADP/ATP carrier imports ADP from the cytosol and exports ATP from the mitochondrial matrix, which are …
The ADP and ATP transport in mitochondria and its carrier.
Klingenberg M. Klingenberg M. Biochim Biophys Acta. 2008 Oct;1778(10):1978-2021. doi: 10.1016/j.bbamem.2008.04.011. Epub 2008 May 2. Biochim Biophys Acta. 2008. PMID: 18510943 Free article. Review.
Amidst the labours, 40 or more years ago, of unravelling the role of mitochondrial compartments and of the two membranes, the sequence of steps of how ATP arrives in the cytosol became a major issue. When the dust settled, a picture emerged where ATP is exported acr …
Amidst the labours, 40 or more years ago, of unravelling the role of mitochondrial compartments and of the two membranes, the sequence of st …
Biochemical studies on the structure-function relationship of major drug transporters in the ATP-binding cassette family and solute carrier family.
Hong M. Hong M. Adv Drug Deliv Rev. 2017 Jul 1;116:3-20. doi: 10.1016/j.addr.2016.06.003. Epub 2016 Jun 15. Adv Drug Deliv Rev. 2017. PMID: 27317853 Review.
Over the years, quite a few structure-function relationship information had been obtained for members of the two major transporter families: the ATP-binding cassette family and the solute carrier family. Critical structural features of drug transporters include tran …
Over the years, quite a few structure-function relationship information had been obtained for members of the two major transporter families: …
Transport of adenine nucleotides in the mitochondria of Saccharomyces cerevisiae: interactions between the ADP/ATP carriers and the ATP-Mg/Pi carrier.
Traba J, Satrústegui J, del Arco A. Traba J, et al. Mitochondrion. 2009 Apr;9(2):79-85. doi: 10.1016/j.mito.2009.01.001. Epub 2009 Jan 17. Mitochondrion. 2009. PMID: 19460304 Review.
The ADP/ATP and ATP-Mg/Pi carriers are widespread among eukaryotes and constitute two systems to transport adenine nucleotides in mitochondria. ADP/ATP carriers carry out an electrogenic exchange of ADP for ATP essential for oxidative pho …
The ADP/ATP and ATP-Mg/Pi carriers are widespread among eukaryotes and constitute two systems to transport adenine nucl …
Heterogeneous ATP patterns in microvascular networks.
Gou Z, Zhang H, Misbah C. Gou Z, et al. J R Soc Interface. 2023 Jul;20(204):20230186. doi: 10.1098/rsif.2023.0186. Epub 2023 Jul 19. J R Soc Interface. 2023. PMID: 37464803
ATP is not only an energy carrier but also serves as an important signalling molecule in many physiological processes. Abnormal ATP level in blood vessel is known to be related to several pathologies, such as inflammation, hypoxia and atherosclerosis. ...
ATP is not only an energy carrier but also serves as an important signalling molecule in many physiological processes. Abnorma …
Dialectics in carrier research: the ADP/ATP carrier and the uncoupling protein.
Klingenberg M. Klingenberg M. J Bioenerg Biomembr. 1993 Oct;25(5):447-57. doi: 10.1007/BF01108402. J Bioenerg Biomembr. 1993. PMID: 8132485 Review.
The pioneer role of research on the AAC, not only for the mitochondrial but also for other carriers, and the present state of their structure-function relationship is reviewed. The function of UCP as a highly regulated H+ carrier is described in contrast to t …
The pioneer role of research on the AAC, not only for the mitochondrial but also for other carriers, and the present state of …
Hypertrophic cardiomyopathy mutations in MYBPC3 dysregulate myosin.
Toepfer CN, Wakimoto H, Garfinkel AC, McDonough B, Liao D, Jiang J, Tai AC, Gorham JM, Lunde IG, Lun M, Lynch TL 4th, McNamara JW, Sadayappan S, Redwood CS, Watkins HC, Seidman JG, Seidman CE. Toepfer CN, et al. Sci Transl Med. 2019 Jan 23;11(476):eaat1199. doi: 10.1126/scitranslmed.aat1199. Sci Transl Med. 2019. PMID: 30674652 Free PMC article.
Depletion of cMyBPC also altered dynamic myosin conformations during relaxation, enhancing the myosin state that enables ATP hydrolysis and thin filament interactions while reducing the super relaxed conformation associated with energy conservation. ...
Depletion of cMyBPC also altered dynamic myosin conformations during relaxation, enhancing the myosin state that enables ATP h …
Novel US-CpHMD Protocol to Study the Protonation-Dependent Mechanism of the ATP/ADP Carrier.
Oliveira NFB, Machuqueiro M. Oliveira NFB, et al. J Chem Inf Model. 2022 May 23;62(10):2550-2560. doi: 10.1021/acs.jcim.2c00233. Epub 2022 Apr 20. J Chem Inf Model. 2022. PMID: 35442654 Free PMC article.
We have designed a protocol combining constant-pH molecular dynamics (CpHMD) simulations with an umbrella sampling (US) scheme (US-CpHMD) to study the mechanism of ADP/ATP transport (import and export) by their inner mitochondrial membrane carrier protein [ADP/AT …
We have designed a protocol combining constant-pH molecular dynamics (CpHMD) simulations with an umbrella sampling (US) scheme (US-CpHMD) to …
12,355 results
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