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The short-chain fatty acid acetate reduces appetite via a central homeostatic mechanism.
Frost G, Sleeth ML, Sahuri-Arisoylu M, Lizarbe B, Cerdan S, Brody L, Anastasovska J, Ghourab S, Hankir M, Zhang S, Carling D, Swann JR, Gibson G, Viardot A, Morrison D, Louise Thomas E, Bell JD. Frost G, et al. Among authors: anastasovska j. Nat Commun. 2014 Apr 29;5:3611. doi: 10.1038/ncomms4611. Nat Commun. 2014. PMID: 24781306 Free PMC article.
Thyroid Hormone Receptor Beta in the Ventromedial Hypothalamus Is Essential for the Physiological Regulation of Food Intake and Body Weight.
Hameed S, Patterson M, Dhillo WS, Rahman SA, Ma Y, Holton C, Gogakos A, Yeo GSH, Lam BYH, Polex-Wolf J, Fenske W, Bell J, Anastasovska J, Samarut J, Bloom SR, Bassett JHD, Williams GR, Gardiner JV. Hameed S, et al. Among authors: anastasovska j. Cell Rep. 2017 Jun 13;19(11):2202-2209. doi: 10.1016/j.celrep.2017.05.066. Cell Rep. 2017. PMID: 28614708 Free PMC article.
Kisspeptin signaling in the amygdala modulates reproductive hormone secretion.
Comninos AN, Anastasovska J, Sahuri-Arisoylu M, Li X, Li S, Hu M, Jayasena CN, Ghatei MA, Bloom SR, Matthews PM, O'Byrne KT, Bell JD, Dhillo WS. Comninos AN, et al. Among authors: anastasovska j. Brain Struct Funct. 2016 May;221(4):2035-47. doi: 10.1007/s00429-015-1024-9. Epub 2015 Mar 11. Brain Struct Funct. 2016. PMID: 25758403 Free PMC article.
Cerebral activation by fasting induces lactate accumulation in the hypothalamus.
Violante IR, Anastasovska J, Sanchez-Canon GJ, Rodrigues TB, Righi V, Nieto-Charques L, Parkinson JR, Bloom SR, Bell JD, Cerdán S. Violante IR, et al. Among authors: anastasovska j. Magn Reson Med. 2009 Aug;62(2):279-83. doi: 10.1002/mrm.22010. Magn Reson Med. 2009. PMID: 19526502 Free article.