Anderson ME - Search Results

1

Self-hydrolyzing maleimides improve the stability and pharmacological properties of antibody-drug conjugates.

Lyon RP, Setter JR, Bovee TD, Doronina SO, Hunter JH, Anderson ME, Balasubramanian CL, Duniho SM, Leiske CI, Li F, Senter PD. Lyon RP, et al. Among authors: anderson me. Nat Biotechnol. 2014 Oct;32(10):1059-62. doi: 10.1038/nbt.2968. Epub 2014 Sep 7. Nat Biotechnol. 2014. PMID: 25194818

2

CD133/prominin-1 is a potential therapeutic target for antibody-drug conjugates in hepatocellular and gastric cancers.

Smith LM, Nesterova A, Ryan MC, Duniho S, Jonas M, Anderson M, Zabinski RF, Sutherland MK, Gerber HP, Van Orden KL, Moore PA, Ruben SM, Carter PJ. Smith LM, et al. Br J Cancer. 2008 Jul 8;99(1):100-9. doi: 10.1038/sj.bjc.6604437. Epub 2008 Jun 10. Br J Cancer. 2008. PMID: 18542072 Free PMC article.

3

Engineered anti-CD70 antibody-drug conjugate with increased therapeutic index.

McDonagh CF, Kim KM, Turcott E, Brown LL, Westendorf L, Feist T, Sussman D, Stone I, Anderson M, Miyamoto J, Lyon R, Alley SC, Gerber HP, Carter PJ. McDonagh CF, et al. Mol Cancer Ther. 2008 Sep;7(9):2913-23. doi: 10.1158/1535-7163.MCT-08-0295. Mol Cancer Ther. 2008. PMID: 18790772 Free article.

4

Novel peptide linkers for highly potent antibody-auristatin conjugate.

Doronina SO, Bovee TD, Meyer DW, Miyamoto JB, Anderson ME, Morris-Tilden CA, Senter PD. Doronina SO, et al. Among authors: anderson me. Bioconjug Chem. 2008 Oct;19(10):1960-3. doi: 10.1021/bc800289a. Epub 2008 Sep 20. Bioconjug Chem. 2008. PMID: 18803412

5

Novel immunoconjugates comprised of streptonigrin and 17-amino-geldanamycin attached via a dipeptide-p-aminobenzyl-amine linker system.

Burke PJ, Toki BE, Meyer DW, Miyamoto JB, Kissler KM, Anderson M, Senter PD, Jeffrey SC. Burke PJ, et al. Bioorg Med Chem Lett. 2009 May 15;19(10):2650-3. doi: 10.1016/j.bmcl.2009.03.145. Epub 2009 Apr 5. Bioorg Med Chem Lett. 2009. PMID: 19386499

6

Design, synthesis, and biological evaluation of antibody-drug conjugates comprised of potent camptothecin analogues.

Burke PJ, Senter PD, Meyer DW, Miyamoto JB, Anderson M, Toki BE, Manikumar G, Wani MC, Kroll DJ, Jeffrey SC. Burke PJ, et al. Bioconjug Chem. 2009 Jun;20(6):1242-50. doi: 10.1021/bc9001097. Bioconjug Chem. 2009. PMID: 19469529

7

The pharmacologic basis for antibody-auristatin conjugate activity.

Alley SC, Zhang X, Okeley NM, Anderson M, Law CL, Senter PD, Benjamin DR. Alley SC, et al. J Pharmacol Exp Ther. 2009 Sep;330(3):932-8. doi: 10.1124/jpet.109.155549. Epub 2009 Jun 4. J Pharmacol Exp Ther. 2009. PMID: 19498104

8

Targeting pancreatic and ovarian carcinomas using the auristatin-based anti-CD70 antibody-drug conjugate SGN-75.

Ryan MC, Kostner H, Gordon KA, Duniho S, Sutherland MK, Yu C, Kim KM, Nesterova A, Anderson M, McEarchern JA, Law CL, Smith LM. Ryan MC, et al. Br J Cancer. 2010 Aug 24;103(5):676-84. doi: 10.1038/sj.bjc.6605816. Epub 2010 Jul 27. Br J Cancer. 2010. PMID: 20664585 Free PMC article.

9

Development of orally active inhibitors of protein and cellular fucosylation.

Okeley NM, Alley SC, Anderson ME, Boursalian TE, Burke PJ, Emmerton KM, Jeffrey SC, Klussman K, Law CL, Sussman D, Toki BE, Westendorf L, Zeng W, Zhang X, Benjamin DR, Senter PD. Okeley NM, et al. Among authors: anderson me. Proc Natl Acad Sci U S A. 2013 Apr 2;110(14):5404-9. doi: 10.1073/pnas.1222263110. Epub 2013 Mar 14. Proc Natl Acad Sci U S A. 2013. PMID: 23493549 Free PMC article.

10

A potent anti-CD70 antibody-drug conjugate combining a dimeric pyrrolobenzodiazepine drug with site-specific conjugation technology.

Jeffrey SC, Burke PJ, Lyon RP, Meyer DW, Sussman D, Anderson M, Hunter JH, Leiske CI, Miyamoto JB, Nicholas ND, Okeley NM, Sanderson RJ, Stone IJ, Zeng W, Gregson SJ, Masterson L, Tiberghien AC, Howard PW, Thurston DE, Law CL, Senter PD. Jeffrey SC, et al. Bioconjug Chem. 2013 Jul 17;24(7):1256-63. doi: 10.1021/bc400217g. Epub 2013 Jun 28. Bioconjug Chem. 2013. PMID: 23808985

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