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The functional interplay between EGFR overexpression, hTERT activation, and p53 mutation in esophageal epithelial cells with activation of stromal fibroblasts induces tumor development, invasion, and differentiation.
Okawa T, Michaylira CZ, Kalabis J, Stairs DB, Nakagawa H, Andl CD, Johnstone CN, Klein-Szanto AJ, El-Deiry WS, Cukierman E, Herlyn M, Rustgi AK. Okawa T, et al. Genes Dev. 2007 Nov 1;21(21):2788-803. doi: 10.1101/gad.1544507. Genes Dev. 2007. PMID: 17974918 Free PMC article.
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