Andrews SP - Search Results

1

Total synthesis of thapsigargin, a potent SERCA pump inhibitor.

Ball M, Andrews SP, Wierschem F, Cleator E, Smith MD, Ley SV. Ball M, et al. Among authors: andrews sp. Org Lett. 2007 Feb 15;9(4):663-6. doi: 10.1021/ol062947x. Epub 2007 Jan 27. Org Lett. 2007. PMID: 17256950

2

Design and total synthesis of unnatural analogues of the sub-nanomolar SERCA inhibitor thapsigargin.

Andrews SP, Tait MM, Ball M, Ley SV. Andrews SP, et al. Org Biomol Chem. 2007 May 7;5(9):1427-36. doi: 10.1039/b702481a. Epub 2007 Mar 23. Org Biomol Chem. 2007. PMID: 17464412

3

Total synthesis of five thapsigargins: guaianolide natural products exhibiting sub-nanomolar SERCA inhibition.

Andrews SP, Ball M, Wierschem F, Cleator E, Oliver S, Högenauer K, Simic O, Antonello A, Hünger U, Smith MD, Ley SV. Andrews SP, et al. Chemistry. 2007;13(20):5688-712. doi: 10.1002/chem.200700302. Chemistry. 2007. PMID: 17508363

4

Convenient preparation and use of a new analytical construct for the analysis and development of solid-phase chemistries.

Andrews SP, Ladlow M. Andrews SP, et al. J Org Chem. 2003 Jul 11;68(14):5525-33. doi: 10.1021/jo034340p. J Org Chem. 2003. PMID: 12839443

5

Automated parallel, multi-step polymer-assisted solution phase (PASP) synthesis of substituted benzimidazole derivatives.

Andrews SP, Jönsson D, Warrington BH, Ladlow M. Andrews SP, et al. Comb Chem High Throughput Screen. 2004 Mar;7(2):161-76. doi: 10.2174/138620704773120847. Comb Chem High Throughput Screen. 2004. PMID: 15032663

6

Size and composition of membrane protein clusters predicted by Monte Carlo analysis.

Goldman J, Andrews S, Bray D. Goldman J, et al. Eur Biophys J. 2004 Oct;33(6):506-12. doi: 10.1007/s00249-004-0391-6. Epub 2004 Mar 2. Eur Biophys J. 2004. PMID: 14997356

7

Autophagy and Neurodegeneration: Pathogenic Mechanisms and Therapeutic Opportunities.

Menzies FM, Fleming A, Caricasole A, Bento CF, Andrews SP, Ashkenazi A, Füllgrabe J, Jackson A, Jimenez Sanchez M, Karabiyik C, Licitra F, Lopez Ramirez A, Pavel M, Puri C, Renna M, Ricketts T, Schlotawa L, Vicinanza M, Won H, Zhu Y, Skidmore J, Rubinsztein DC. Menzies FM, et al. Among authors: andrews sp. Neuron. 2017 Mar 8;93(5):1015-1034. doi: 10.1016/j.neuron.2017.01.022. Neuron. 2017. PMID: 28279350 Free article. Review.

8

The rational design of ARUK2007145, a dual inhibitor of the α and γ isoforms of the lipid kinase phosphatidylinositol 5-phosphate 4-kinase (PI5P4K).

Aldred GG, Rooney TPC, Willems HMG, Boffey HK, Green C, Winpenny D, Skidmore J, Clarke JH, Andrews SP. Aldred GG, et al. Among authors: andrews sp. RSC Med Chem. 2023 Aug 23;14(10):2035-2047. doi: 10.1039/d3md00355h. eCollection 2023 Oct 18. RSC Med Chem. 2023. PMID: 37859710 Free PMC article.

9

Creating an Innovative Global Health Clinical Experience During the COVID-19 Pandemic.

Andrews SP. Andrews SP. J Radiol Nurs. 2023 Jun;42(2):217-219. doi: 10.1016/j.jradnu.2023.03.010. Epub 2023 Apr 5. J Radiol Nurs. 2023. PMID: 37342526 Free PMC article.

10

Identification of ARUK2002821 as an isoform-selective PI5P4Kα inhibitor.

Willems HMG, Edwards S, Boffey HK, Chawner SJ, Green C, Romero T, Winpenny D, Skidmore J, Clarke JH, Andrews SP. Willems HMG, et al. Among authors: andrews sp. RSC Med Chem. 2023 Apr 17;14(5):934-946. doi: 10.1039/d3md00039g. eCollection 2023 May 25. RSC Med Chem. 2023. PMID: 37252102 Free PMC article.

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