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Antifibrinolytics reduce blood loss in adult spinal deformity surgery: a prospective, randomized controlled trial.
Peters A, Verma K, Slobodyanyuk K, Cheriyan T, Hoelscher C, Schwab F, Lonner B, Huncke T, Lafage V, Errico T. Peters A, et al. Spine (Phila Pa 1976). 2015 Apr 15;40(8):E443-9. doi: 10.1097/BRS.0000000000000799. Spine (Phila Pa 1976). 2015. PMID: 25868100 Clinical Trial.
SUMMARY OF BACKGROUND DATA: Spine deformity surgery usually involves substantial blood loss. The antifibrinolytics TXA and EACA have been shown to improve hemostasis in large blood loss surgical procedures. ...EACA ha …
SUMMARY OF BACKGROUND DATA: Spine deformity surgery usually involves substantial blood loss. The antifibrinol …
Randomized, controlled trial of two tranexamic acid dosing protocols in adult spinal deformity surgery.
Clohisy JCF, Lenke LG, Dafrawy MHE, Wolfe RC, Frazier E, Kelly MP. Clohisy JCF, et al. Spine Deform. 2022 Nov;10(6):1399-1406. doi: 10.1007/s43390-022-00539-z. Epub 2022 Jun 25. Spine Deform. 2022. PMID: 35751772 Clinical Trial.
BACKGROUND: Tranexamic acid (TXA) is an anti-fibrinolytic effective in reducing blood loss in orthopedic surgery. The appropriate dosing protocol for adult spinal deformity (ASD) surgery is not known. ...Standard demographic …
BACKGROUND: Tranexamic acid (TXA) is an anti-fibrinolytic effective in reducing blood loss in orthopedic surgery …
A prospective, randomized, double-blinded single-site control study comparing blood loss prevention of tranexamic acid (TXA) to epsilon aminocaproic acid (EACA) for corrective spinal surgery.
Verma K, Errico TJ, Vaz KM, Lonner BS. Verma K, et al. BMC Surg. 2010 Apr 6;10:13. doi: 10.1186/1471-2482-10-13. BMC Surg. 2010. PMID: 20370916 Free PMC article. Clinical Trial.
BACKGROUND: Multilevel spinal fusion surgery has typically been associated with significant blood loss. To limit both the need for transfusions and co-morbidities associated with blood loss, the use of anti-fibrinolytic agents has …
BACKGROUND: Multilevel spinal fusion surgery has typically been associated with significant blood loss. To limit …