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Hypermutated tumours in the era of immunotherapy: The paradigm of personalised medicine.
Nebot-Bral L, Brandao D, Verlingue L, Rouleau E, Caron O, Despras E, El-Dakdouki Y, Champiat S, Aoufouchi S, Leary A, Marabelle A, Malka D, Chaput N, Kannouche PL. Nebot-Bral L, et al. Among authors: aoufouchi s. Eur J Cancer. 2017 Oct;84:290-303. doi: 10.1016/j.ejca.2017.07.026. Epub 2017 Aug 29. Eur J Cancer. 2017. PMID: 28846956 Review.
Overcoming resistance to αPD-1 of MMR-deficient tumors with high tumor-induced neutrophils levels by combination of αCTLA-4 and αPD-1 blockers.
Nebot-Bral L, Hollebecque A, Yurchenko AA, de Forceville L, Danjou M, Jouniaux JM, Rosa RCA, Pouvelle C, Aoufouchi S, Vuagnat P, Smolenschi C, Colomba E, Leary A, Marabelle A, Scoazec JY, Cassard L, Nikolaev S, Chaput N, Kannouche P. Nebot-Bral L, et al. Among authors: aoufouchi s. J Immunother Cancer. 2022 Jul;10(7):e005059. doi: 10.1136/jitc-2022-005059. J Immunother Cancer. 2022. PMID: 35896284 Free PMC article.
B-cell tumor development in Tet2-deficient mice.
Mouly E, Ghamlouch H, Della-Valle V, Scourzic L, Quivoron C, Roos-Weil D, Pawlikowska P, Saada V, Diop MK, Lopez CK, Fontenay M, Dessen P, Touw IP, Mercher T, Aoufouchi S, Bernard OA. Mouly E, et al. Among authors: aoufouchi s. Blood Adv. 2018 Mar 27;2(6):703-714. doi: 10.1182/bloodadvances.2017014118. Blood Adv. 2018. PMID: 29581109 Free PMC article.
TET2 Deficiency Causes Germinal Center Hyperplasia, Impairs Plasma Cell Differentiation, and Promotes B-cell Lymphomagenesis.
Dominguez PM, Ghamlouch H, Rosikiewicz W, Kumar P, Béguelin W, Fontán L, Rivas MA, Pawlikowska P, Armand M, Mouly E, Torres-Martin M, Doane AS, Calvo Fernandez MT, Durant M, Della-Valle V, Teater M, Cimmino L, Droin N, Tadros S, Motanagh S, Shih AH, Rubin MA, Tam W, Aifantis I, Levine RL, Elemento O, Inghirami G, Green MR, Figueroa ME, Bernard OA, Aoufouchi S, Li S, Shaknovich R, Melnick AM. Dominguez PM, et al. Among authors: aoufouchi s. Cancer Discov. 2018 Dec;8(12):1632-1653. doi: 10.1158/2159-8290.CD-18-0657. Epub 2018 Oct 1. Cancer Discov. 2018. PMID: 30274972 Free PMC article.
A Recurrent Activating Missense Mutation in Waldenström Macroglobulinemia Affects the DNA Binding of the ETS Transcription Factor SPI1 and Enhances Proliferation.
Roos-Weil D, Decaudin C, Armand M, Della-Valle V, Diop MK, Ghamlouch H, Ropars V, Hérate C, Lara D, Durot E, Haddad R, Mylonas E, Damm F, Pflumio F, Stoilova B, Metzner M, Elemento O, Dessen P, Camara-Clayette V, Cosset FL, Verhoeyen E, Leblond V, Ribrag V, Cornillet-Lefebvre P, Rameau P, Azar N, Charlotte F, Morel P, Charbonnier JB, Vyas P, Mercher T, Aoufouchi S, Droin N, Guillouf C, Nguyen-Khac F, Bernard OA. Roos-Weil D, et al. Among authors: aoufouchi s. Cancer Discov. 2019 Jun;9(6):796-811. doi: 10.1158/2159-8290.CD-18-0873. Epub 2019 Apr 24. Cancer Discov. 2019. PMID: 31018969
Ig gene hypermutation: a mechanism is due.
Weill JC, Bertocci B, Faili A, Aoufouchi S, Frey S, De Smet A, Storck S, Dahan A, Delbos F, Weller S, Flatter E, Reynaud CA. Weill JC, et al. Among authors: aoufouchi s. Adv Immunol. 2002;80:183-202. doi: 10.1016/s0065-2776(02)80015-3. Adv Immunol. 2002. PMID: 12078481 Review. No abstract available.
50 results