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The amino acid exchange R28E in ciliary neurotrophic factor (CNTF) abrogates interleukin-6 receptor-dependent but retains CNTF receptor-dependent signaling via glycoprotein 130 (gp130)/leukemia inhibitory factor receptor (LIFR).
Wagener EM, Aurich M, Aparicio-Siegmund S, Floss DM, Garbers C, Breusing K, Rabe B, Schwanbeck R, Grötzinger J, Rose-John S, Scheller J. Wagener EM, et al. J Biol Chem. 2014 Jun 27;289(26):18442-50. doi: 10.1074/jbc.M114.568857. Epub 2014 May 6. J Biol Chem. 2014. PMID: 24802752 Free PMC article.
Recombinant p35 from bacteria can form Interleukin (IL-)12, but Not IL-35.
Aparicio-Siegmund S, Moll JM, Lokau J, Grusdat M, Schröder J, Plöhn S, Rose-John S, Grötzinger J, Lang PA, Scheller J, Garbers C. Aparicio-Siegmund S, et al. PLoS One. 2014 Sep 26;9(9):e107990. doi: 10.1371/journal.pone.0107990. eCollection 2014. PLoS One. 2014. PMID: 25259790 Free PMC article.
Proteolytic Cleavage Governs Interleukin-11 Trans-signaling.
Lokau J, Nitz R, Agthe M, Monhasery N, Aparicio-Siegmund S, Schumacher N, Wolf J, Möller-Hackbarth K, Waetzig GH, Grötzinger J, Müller-Newen G, Rose-John S, Scheller J, Garbers C. Lokau J, et al. Among authors: aparicio siegmund s. Cell Rep. 2016 Feb 23;14(7):1761-1773. doi: 10.1016/j.celrep.2016.01.053. Epub 2016 Feb 11. Cell Rep. 2016. PMID: 26876177 Free article.
Cellular senescence or EGFR signaling induces Interleukin 6 (IL-6) receptor expression controlled by mammalian target of rapamycin (mTOR).
Garbers C, Kuck F, Aparicio-Siegmund S, Konzak K, Kessenbrock M, Sommerfeld A, Häussinger D, Lang PA, Brenner D, Mak TW, Rose-John S, Essmann F, Schulze-Osthoff K, Piekorz RP, Scheller J. Garbers C, et al. Cell Cycle. 2013 Nov 1;12(21):3421-32. doi: 10.4161/cc.26431. Epub 2013 Sep 18. Cell Cycle. 2013. PMID: 24047696 Free PMC article.
16 results