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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1972 3
1973 3
1975 1
1976 2
1977 2
1982 1
1983 1
1986 1
1988 3
1990 1
1991 2
1992 3
1993 1
1994 1
1995 2
1996 3
1997 3
1999 1
2000 1
2001 3
2002 1
2003 2
2004 4
2005 2
2006 3
2007 7
2008 2
2009 4
2010 1
2011 5
2012 3
2013 3
2014 2
2015 3
2016 3
2017 2
2018 5
2019 5
2020 6
2021 2
2022 5
2023 1
2024 0

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106 results

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Page 1
Total Synthesis of Loroxanthin.
Yamano Y, Tanabe M, Shimada A, Wada A. Yamano Y, et al. Mar Drugs. 2022 Oct 24;20(11):658. doi: 10.3390/md20110658. Mar Drugs. 2022. PMID: 36354981 Free PMC article.
The first total synthesis of loroxanthin (1) was accomplished by Horner-Wadsworth-Emmons reaction of C(25)-apocarotenal 8 having a silyl-protected 19-hydroxy moiety with C(15)-phosphonate 25 bearing a silyl-protected 3-hydroxy-epsilon-end group. Preparation of apocarote …
The first total synthesis of loroxanthin (1) was accomplished by Horner-Wadsworth-Emmons reaction of C(25)-apocarotenal 8 having a si …
Enzymology of vertebrate carotenoid oxygenases.
Harrison EH, Kopec RE. Harrison EH, et al. Biochim Biophys Acta Mol Cell Biol Lipids. 2020 Nov;1865(11):158653. doi: 10.1016/j.bbalip.2020.158653. Epub 2020 Feb 5. Biochim Biophys Acta Mol Cell Biol Lipids. 2020. PMID: 32035229 Free PMC article. Review.
Thus, BCO1 is the enzyme responsible for the conversion of provitamin A carotenoids to vitamin A. It also cleaves the 15,15' bond of beta-apocarotenals to yield retinal and of lycopene to yield apo-15-lycopenal. beta-Carotene 9',10'-dioxygenase (BCO2) catalyzes the cleavag …
Thus, BCO1 is the enzyme responsible for the conversion of provitamin A carotenoids to vitamin A. It also cleaves the 15,15' bond of beta- …
An in silico study of the citrus dioxygenases CCD4 family substrates.
Vega-Teijido M, Cantero J, Rodrigo MJ, López C, Zunini MP. Vega-Teijido M, et al. J Biomol Struct Dyn. 2019 May;37(8):2086-2097. doi: 10.1080/07391102.2018.1477619. Epub 2018 Nov 5. J Biomol Struct Dyn. 2019. PMID: 30044177
Among them, CCD4b was the first case described of a dioxygenase that cleaves carotenoids C(40) in the double bond 7', 8' or 7, 8, generating beta-citraurin or 8-beta-apocarotenal. Here we report the three-dimensional structures of CCD4a and CCD4b, modeled by sequence homol …
Among them, CCD4b was the first case described of a dioxygenase that cleaves carotenoids C(40) in the double bond 7', 8' or 7, 8, generating …
Heterologous expression of Bixa orellana cleavage dioxygenase 4-3 drives crocin but not bixin biosynthesis.
Frusciante S, Demurtas OC, Sulli M, Mini P, Aprea G, Diretto G, Karcher D, Bock R, Giuliano G. Frusciante S, et al. Plant Physiol. 2022 Mar 4;188(3):1469-1482. doi: 10.1093/plphys/kiab583. Plant Physiol. 2022. PMID: 34919714 Free PMC article.
Two previous reports claimed to have isolated the carotenoid cleavage dioxygenase (CCD) responsible for the production of the putative precursor of bixin, the C24 apocarotenal bixin dialdehyde. We re-assessed the activity of six Bixa CCDs and found that none of them produc …
Two previous reports claimed to have isolated the carotenoid cleavage dioxygenase (CCD) responsible for the production of the putative precu …
Light Increases Astaxanthin Absorbance in Acetone Solution through Isomerization Reactions.
Virchenko O, Stefánsson T. Virchenko O, et al. Molecules. 2023 Jan 14;28(2):847. doi: 10.3390/molecules28020847. Molecules. 2023. PMID: 36677904 Free PMC article.
The greater HPLC values' elevation was related not only to the increase of astaxanthin absorbance, but also to light-dependent degradation of internal standard apocarotenal. The findings confirm a poor robustness of the conventional analytical procedure for astaxanthin qua …
The greater HPLC values' elevation was related not only to the increase of astaxanthin absorbance, but also to light-dependent degradation o …
Molecular Properties of β-Carotene Oxygenases and Their Potential in Industrial Production of Vitamin A and Its Derivatives.
Shin KC, Seo MJ, Kim YS, Yeom SJ. Shin KC, et al. Antioxidants (Basel). 2022 Jun 16;11(6):1180. doi: 10.3390/antiox11061180. Antioxidants (Basel). 2022. PMID: 35740077 Free PMC article. Review.
beta-Carotene 15,15'-oxygenase (BCO1) and beta-carotene 9',10'-oxygenase (BCO2) are potential producers of vitamin A derivatives, since they can catalyze the oxidative cleavage of dietary provitamin A carotenoids to retinoids and derivative such as apocarotenal. Retinoids …
beta-Carotene 15,15'-oxygenase (BCO1) and beta-carotene 9',10'-oxygenase (BCO2) are potential producers of vitamin A derivatives, since they …
Carotenoids, β-Apocarotenoids, and Retinoids: The Long and the Short of It.
Harrison EH. Harrison EH. Nutrients. 2022 Mar 28;14(7):1411. doi: 10.3390/nu14071411. Nutrients. 2022. PMID: 35406024 Free PMC article. Review.
Chemical oxidation of the other double bonds leads to the generation of other beta-apocarotenals. Like retinal, some of these beta-apocarotenals are metabolically oxidized to the corresponding beta-apocarotenoic acids or reduced to the beta-apocarotenols, which in t …
Chemical oxidation of the other double bonds leads to the generation of other beta-apocarotenals. Like retinal, some of these beta- …
Apocarotenoids produced from β-carotene by dioxygenases from Mucor circinelloides.
Alcalde E, Cerdá-Olmedo E, Al-Babili S. Alcalde E, et al. Microbiology (Reading). 2019 Apr;165(4):433-438. doi: 10.1099/mic.0.000762. Epub 2019 Feb 14. Microbiology (Reading). 2019. PMID: 30762519 Free article.
The first of these products, CarS, cleaved the C40 beta-carotene into the C15 precursor of cyclofarnesoids and a C25 apocarotenal that was converted by the second enzyme, AcaA, into the C18 precursor of trisporoids and the C7 precursor of methylhexanoids. ...
The first of these products, CarS, cleaved the C40 beta-carotene into the C15 precursor of cyclofarnesoids and a C25 apocarotenal tha …
106 results