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ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease.
Lustbader JW, Cirilli M, Lin C, Xu HW, Takuma K, Wang N, Caspersen C, Chen X, Pollak S, Chaney M, Trinchese F, Liu S, Gunn-Moore F, Lue LF, Walker DG, Kuppusamy P, Zewier ZL, Arancio O, Stern D, Yan SS, Wu H. Lustbader JW, et al. Among authors: arancio o. Science. 2004 Apr 16;304(5669):448-52. doi: 10.1126/science.1091230. Science. 2004. PMID: 15087549
RAGE potentiates Abeta-induced perturbation of neuronal function in transgenic mice.
Arancio O, Zhang HP, Chen X, Lin C, Trinchese F, Puzzo D, Liu S, Hegde A, Yan SF, Stern A, Luddy JS, Lue LF, Walker DG, Roher A, Buttini M, Mucke L, Li W, Schmidt AM, Kindy M, Hyslop PA, Stern DM, Du Yan SS. Arancio O, et al. EMBO J. 2004 Oct 13;23(20):4096-105. doi: 10.1038/sj.emboj.7600415. Epub 2004 Sep 30. EMBO J. 2004. PMID: 15457210 Free PMC article.
Receptor for advanced glycation end product-dependent activation of p38 mitogen-activated protein kinase contributes to amyloid-beta-mediated cortical synaptic dysfunction.
Origlia N, Righi M, Capsoni S, Cattaneo A, Fang F, Stern DM, Chen JX, Schmidt AM, Arancio O, Yan SD, Domenici L. Origlia N, et al. Among authors: arancio o. J Neurosci. 2008 Mar 26;28(13):3521-30. doi: 10.1523/JNEUROSCI.0204-08.2008. J Neurosci. 2008. PMID: 18367618 Free PMC article.
Retromer deficiency observed in Alzheimer's disease causes hippocampal dysfunction, neurodegeneration, and Abeta accumulation.
Muhammad A, Flores I, Zhang H, Yu R, Staniszewski A, Planel E, Herman M, Ho L, Kreber R, Honig LS, Ganetzky B, Duff K, Arancio O, Small SA. Muhammad A, et al. Among authors: arancio o. Proc Natl Acad Sci U S A. 2008 May 20;105(20):7327-32. doi: 10.1073/pnas.0802545105. Epub 2008 May 14. Proc Natl Acad Sci U S A. 2008. PMID: 18480253 Free PMC article.
MAPK, beta-amyloid and synaptic dysfunction: the role of RAGE.
Origlia N, Arancio O, Domenici L, Yan SS. Origlia N, et al. Among authors: arancio o. Expert Rev Neurother. 2009 Nov;9(11):1635-45. doi: 10.1586/ern.09.107. Expert Rev Neurother. 2009. PMID: 19903023 Free PMC article. Review.
206 results