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CAR T therapy beyond cancer: the evolution of a living drug.
Baker DJ, Arany Z, Baur JA, Epstein JA, June CH. Baker DJ, et al. Among authors: arany z. Nature. 2023 Jul;619(7971):707-715. doi: 10.1038/s41586-023-06243-w. Epub 2023 Jul 26. Nature. 2023. PMID: 37495877 Review.
A branched-chain amino acid metabolite drives vascular fatty acid transport and causes insulin resistance.
Jang C, Oh SF, Wada S, Rowe GC, Liu L, Chan MC, Rhee J, Hoshino A, Kim B, Ibrahim A, Baca LG, Kim E, Ghosh CC, Parikh SM, Jiang A, Chu Q, Forman DE, Lecker SH, Krishnaiah S, Rabinowitz JD, Weljie AM, Baur JA, Kasper DL, Arany Z. Jang C, et al. Among authors: arany z. Nat Med. 2016 Apr;22(4):421-6. doi: 10.1038/nm.4057. Epub 2016 Mar 7. Nat Med. 2016. PMID: 26950361 Free PMC article.
The ADP/ATP translocase drives mitophagy independent of nucleotide exchange.
Hoshino A, Wang WJ, Wada S, McDermott-Roe C, Evans CS, Gosis B, Morley MP, Rathi KS, Li J, Li K, Yang S, McManus MJ, Bowman C, Potluri P, Levin M, Damrauer S, Wallace DC, Holzbaur ELF, Arany Z. Hoshino A, et al. Among authors: arany z. Nature. 2019 Nov;575(7782):375-379. doi: 10.1038/s41586-019-1667-4. Epub 2019 Oct 16. Nature. 2019. PMID: 31618756 Free PMC article.
Transcriptional control of preadipocyte determination by Zfp423.
Gupta RK, Arany Z, Seale P, Mepani RJ, Ye L, Conroe HM, Roby YA, Kulaga H, Reed RR, Spiegelman BM. Gupta RK, et al. Among authors: arany z. Nature. 2010 Mar 25;464(7288):619-23. doi: 10.1038/nature08816. Epub 2010 Mar 3. Nature. 2010. PMID: 20200519 Free PMC article.
The small intestine shields the liver from fructose-induced steatosis.
Jang C, Wada S, Yang S, Gosis B, Zeng X, Zhang Z, Shen Y, Lee G, Arany Z, Rabinowitz JD. Jang C, et al. Among authors: arany z. Nat Metab. 2020 Jul;2(7):586-593. doi: 10.1038/s42255-020-0222-9. Epub 2020 Jun 22. Nat Metab. 2020. PMID: 32694791 Free PMC article.
A randomized placebo-controlled clinical trial for pharmacological activation of BCAA catabolism in patients with type 2 diabetes.
Vanweert F, Neinast M, Tapia EE, van de Weijer T, Hoeks J, Schrauwen-Hinderling VB, Blair MC, Bornstein MR, Hesselink MKC, Schrauwen P, Arany Z, Phielix E. Vanweert F, et al. Among authors: arany z. Nat Commun. 2022 Jun 18;13(1):3508. doi: 10.1038/s41467-022-31249-9. Nat Commun. 2022. PMID: 35717342 Free PMC article. Clinical Trial.
204 results