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Gain-of-function mutation in ubiquitin-ligase KLHL24 causes desmin degradation and dilatation in hiPSC-derived engineered heart tissues.
Vermeer MC, Bolling MC, Bliley JM, Arevalo Gomez KF, Pavez-Giani MG, Kramer D, Romero-Herrera PH, Westenbrink BD, Diercks GF, van den Berg MP, Feinberg AW, Silljé HHW, van der Meer P. Vermeer MC, et al. Among authors: arevalo gomez kf. J Clin Invest. 2021 Jul 22;131(17):e140615. doi: 10.1172/JCI140615. Online ahead of print. J Clin Invest. 2021. PMID: 34292882 Free PMC article.
Human iPSC-Derived Cardiomyocytes of Peripartum Patients With Cardiomyopathy Reveal Aberrant Regulation of Lipid Metabolism.
Hoes MF, Bomer N, Ricke-Hoch M, de Jong TV, Arevalo Gomez KF, Pietzsch S, Hilfiker-Kleiner D, van der Meer P. Hoes MF, et al. Among authors: arevalo gomez kf. Circulation. 2020 Dec 8;142(23):2288-2291. doi: 10.1161/CIRCULATIONAHA.119.044962. Epub 2020 Dec 7. Circulation. 2020. PMID: 33284656 Free PMC article. No abstract available.
Clinical Outcome in KLHL24 Cardiomyopathy.
Vermeer MCSC, Arevalo Gomez KF, Hoes MF, Tromp J, Verdonschot JAJ, Henkens MTHM, Silljé HHW, Bolling MC, van der Meer P. Vermeer MCSC, et al. Among authors: arevalo gomez kf. Circ Genom Precis Med. 2023 Aug;16(4):401-403. doi: 10.1161/CIRCGEN.122.003998. Epub 2023 May 16. Circ Genom Precis Med. 2023. PMID: 37191012 Free PMC article. No abstract available.
Evaluation of Senescence and Its Prevention in Doxorubicin-Induced Cardiotoxicity Using Dynamic Engineered Heart Tissues.
Linders AN, Dias IB, Ovchinnikova ES, Vermeer MCSC, Hoes MF, Markousis Mavrogenis G, Deiman FE, Arevalo Gomez KF, Bliley JM, Nehme J, Vink A, Gietema J, de Boer RA, Westenbrink D, Sillje HHW, Hilfiker-Kleiner D, van Laake LW, Feinberg AW, Demaria M, Bomer N, van der Meer P. Linders AN, et al. Among authors: arevalo gomez kf. JACC CardioOncol. 2023 May 16;5(3):298-315. doi: 10.1016/j.jaccao.2023.03.012. eCollection 2023 Jun. JACC CardioOncol. 2023. PMID: 37397084 Free PMC article.