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2009 1
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21 results

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Page 1
ARHGAP44 expression is associated with the metastasis of osteosarcoma and is a promising prognostic biomarker.
Hu S, Wang W. Hu S, et al. J Orthop Res. 2023 Jun;41(6):1348-1355. doi: 10.1002/jor.25478. Epub 2022 Nov 12. J Orthop Res. 2023. PMID: 36317850 Free article.
High ARHGAP44 expression was associated with metastasis of OS. The OS patients with high ARHGAP44 expression had worse prognosis compared with low ARHGAP44 expression OS patients. ...ARHGAP44 was a potential prognostic biomarker for OS....
High ARHGAP44 expression was associated with metastasis of OS. The OS patients with high ARHGAP44 expression had worse prognos …
ARHGAP44-mediated regulation of the p53/C-myc/Cyclin D1 pathway in modulating the malignant biological behavior of osteosarcoma cells.
Li S, Xue J, Zhang H, Shang G. Li S, et al. J Orthop Surg Res. 2023 Nov 29;18(1):910. doi: 10.1186/s13018-023-04406-z. J Orthop Surg Res. 2023. PMID: 38031136 Free PMC article.
Western blotting was performed to detect the expression of ARHGAP44, p53, C-myc, and Cyclin D1 in osteosarcoma. RESULTS: Biogenic analysis showed that ARHGAP44 was highly expressed in osteosarcoma. ...The downregulation of ARHGAP44 expression reduced the mali …
Western blotting was performed to detect the expression of ARHGAP44, p53, C-myc, and Cyclin D1 in osteosarcoma. RESULTS: Biogenic ana …
Expression Analyses of Rich2/Arhgap44, a Rho Family GTPase-Activating Protein, during Mouse Brain Development.
Goto N, Nishikawa M, Ito H, Noda M, Hamada N, Tabata H, Kinoshita M, Nagata KI. Goto N, et al. Dev Neurosci. 2023;45(1):19-26. doi: 10.1159/000529051. Epub 2023 Jan 11. Dev Neurosci. 2023. PMID: 36630934 Free PMC article.
Rho family small GTPases, such as Rho, Rac, and Cdc42, play essential roles during brain development, by regulating cellular signaling and actin cytoskeletal reorganization. Rich2/Arhgap44, a Rac- and Cdc42-specific GTPase-activating protein, has been reported to be a key …
Rho family small GTPases, such as Rho, Rac, and Cdc42, play essential roles during brain development, by regulating cellular signaling and a …
Mutant p53 promotes cell spreading and migration via ARHGAP44.
Xu J, Jiao J, Xu W, Ji L, Jiang D, Xie S, Kubra S, Li X, Fu J, Xiao J, Zhang B. Xu J, et al. Sci China Life Sci. 2017 Sep;60(9):1019-1029. doi: 10.1007/s11427-016-9040-8. Epub 2017 May 16. Sci China Life Sci. 2017. PMID: 28527113
RNA-Seq analysis suggested that Rho GTPase activating protein 44 (ARHGAP44) is a new target of mutant p53, which suppressed ARHGAP44 transcription. ...Importantly, wt-ARHGAP44 but not mutant ARHGAP44 (R291A) suppressed mutant p53 mediated cell spreadin …
RNA-Seq analysis suggested that Rho GTPase activating protein 44 (ARHGAP44) is a new target of mutant p53, which suppressed ARHGAP …
Dynamic recruitment of the curvature-sensitive protein ArhGAP44 to nanoscale membrane deformations limits exploratory filopodia initiation in neurons.
Galic M, Tsai FC, Collins SR, Matis M, Bandara S, Meyer T. Galic M, et al. Elife. 2014 Dec 15;3:e03116. doi: 10.7554/eLife.03116. Elife. 2014. PMID: 25498153 Free PMC article.
Here, we find that filopodia initiation is suppressed by recruitment of ArhGAP44 to actin-patches that seed filopodia. Recruitment is mediated by binding of a membrane curvature-sensing ArhGAP44 N-BAR domain to plasma membrane sections that were deformed inward by a …
Here, we find that filopodia initiation is suppressed by recruitment of ArhGAP44 to actin-patches that seed filopodia. Recruitment is …
A Novel Gene ARHGAP44 for Longitudinal Changes in Glycated Hemoglobin (HbA1c) in Subjects without Type 2 Diabetes: Evidence from the Long Life Family Study (LLFS) and the Framingham Offspring Study (FOS).
Wang S, Lenzini P, Thygarajan B, Lee JH, Vardarajan BN, Yashin A, Miljkovic I, Warwick Daw E, Lin SJ, Patti G, Brent M, Zmuda JM, Perls TT, Christensen K, Province MA, An P. Wang S, et al. bioRxiv [Preprint]. 2024 May 21:2024.05.16.594575. doi: 10.1101/2024.05.16.594575. bioRxiv. 2024. PMID: 38826208 Free PMC article. Preprint.
In-depth analysis of this locus revealed a variant rs56340929 (explaining 27% of the linkage peak) in the ARHGAP44 gene that was significantly associated with deltaHbA1c. RNA transcription of ARHGAP44 was associated with deltaHbA1c. The Framingham Offspring Study da …
In-depth analysis of this locus revealed a variant rs56340929 (explaining 27% of the linkage peak) in the ARHGAP44 gene that was sign …
A comprehensive landscape of transcription profiles and data resources for human leukemia.
Luo M, Miao YR, Ke YJ, Guo AY, Zhang Q. Luo M, et al. Blood Adv. 2023 Jul 25;7(14):3435-3449. doi: 10.1182/bloodadvances.2022008410. Blood Adv. 2023. PMID: 36595475 Free PMC article.
In addition, a comprehensive analysis of data in LeukemiaDB demonstrates that (1) different leukemia subtypes or cell lines have similar expression distribution of the protein-coding gene and lncRNA; (2) some alternative splicing events are shared among nearly all leukemia subtyp …
In addition, a comprehensive analysis of data in LeukemiaDB demonstrates that (1) different leukemia subtypes or cell lines have similar exp …
Genome-wide association study for loin muscle area of commercial crossbred pigs.
Luan M, Ruan D, Qiu Y, Ye Y, Zhou S, Yang J, Sun Y, Ma F, Wu Z, Yang J, Yang M, Zheng E, Cai G, Huang S. Luan M, et al. Anim Biosci. 2023 Jun;36(6):861-868. doi: 10.5713/ab.22.0407. Epub 2023 Jan 11. Anim Biosci. 2023. PMID: 36634654 Free PMC article.
Based on previous research, we determined two candidate genes (growth hormone receptor [GHR] and 3-oxoacid Co A-transferase 1 [OXCT1]) that are associated with fat deposition and muscle growth and found further additional genes (MYOCD, ARHGAP44, ELAC2, MAP2K4, FBXO4, FBLL1 …
Based on previous research, we determined two candidate genes (growth hormone receptor [GHR] and 3-oxoacid Co A-transferase 1 [OXCT1]) that …
21 results