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Orphan nuclear receptor Nur77 affects cardiomyocyte calcium homeostasis and adverse cardiac remodelling.
Medzikovic L, Schumacher CA, Verkerk AO, van Deel ED, Wolswinkel R, van der Made I, Bleeker N, Cakici D, van den Hoogenhof MM, Meggouh F, Creemers EE, Remme CA, Baartscheer A, de Winter RJ, de Vries CJ, Arkenbout EK, de Waard V. Medzikovic L, et al. Among authors: arkenbout ek. Sci Rep. 2015 Oct 21;5:15404. doi: 10.1038/srep15404. Sci Rep. 2015. PMID: 26486271 Free PMC article.
Nuclear receptors Nur77, Nurr1, and NOR-1 expressed in atherosclerotic lesion macrophages reduce lipid loading and inflammatory responses.
Bonta PI, van Tiel CM, Vos M, Pols TW, van Thienen JV, Ferreira V, Arkenbout EK, Seppen J, Spek CA, van der Poll T, Pannekoek H, de Vries CJ. Bonta PI, et al. Among authors: arkenbout ek. Arterioscler Thromb Vasc Biol. 2006 Oct;26(10):2288-94. doi: 10.1161/01.ATV.0000238346.84458.5d. Epub 2006 Jul 27. Arterioscler Thromb Vasc Biol. 2006. PMID: 16873729
Nuclear receptor Nurr1 is expressed in and is associated with human restenosis and inhibits vascular lesion formation in mice involving inhibition of smooth muscle cell proliferation and inflammation.
Bonta PI, Pols TW, van Tiel CM, Vos M, Arkenbout EK, Rohlena J, Koch KT, de Maat MP, Tanck MW, de Winter RJ, Pannekoek H, Biessen EA, Bot I, de Vries CJ. Bonta PI, et al. Among authors: arkenbout ek. Circulation. 2010 May 11;121(18):2023-32. doi: 10.1161/CIRCULATIONAHA.109.885673. Epub 2010 Apr 26. Circulation. 2010. PMID: 20421523
36 results