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Structure of the activated human minor spliceosome.
Bai R, Wan R, Wang L, Xu K, Zhang Q, Lei J, Shi Y. Bai R, et al. Science. 2021 Mar 19;371(6535):eabg0879. doi: 10.1126/science.abg0879. Epub 2021 Jan 28. Science. 2021. PMID: 33509932
Five newly identified proteins stabilize the conformation of the catalytic center: The zinc finger protein SCNM1 functionally mimics the SF3a complex of the major spliceosome, the RBM48-ARMC7 complex binds the gamma-monomethyl phosphate cap at the 5' end of U6atac snRNA, t …
Five newly identified proteins stabilize the conformation of the catalytic center: The zinc finger protein SCNM1 functionally mimics the SF3 …
Exploring the cell-free total RNA transcriptome in diffuse large B-cell lymphoma and primary mediastinal B-cell lymphoma patients as biomarker source in blood plasma liquid biopsies.
Decruyenaere P, Giuili E, Verniers K, Anckaert J, De Grove K, Van der Linden M, Deeren D, Van Dorpe J, Offner F, Vandesompele J. Decruyenaere P, et al. Front Oncol. 2023 Oct 25;13:1221471. doi: 10.3389/fonc.2023.1221471. eCollection 2023. Front Oncol. 2023. PMID: 37954086 Free PMC article.
High plasma levels of a 9-gene signature (BECN1, PRKCB, COPA, TSC22D3, MAP2K3, UQCRHL, PTMAP4, EHD1, NAP1L1 pseudogene) and a 5-gene signature (FTH1P7, PTMAP4, ATF4, FTH1P8, ARMC7) were significantly associated with inferior progression-free and overall survival in DLBCL p …
High plasma levels of a 9-gene signature (BECN1, PRKCB, COPA, TSC22D3, MAP2K3, UQCRHL, PTMAP4, EHD1, NAP1L1 pseudogene) and a 5-gene signatu …
RNA Binding Motif Protein 48 Is Required for U12 Splicing and Maize Endosperm Differentiation.
Bai F, Corll J, Shodja DN, Davenport R, Feng G, Mudunkothge J, Brigolin CJ, Martin F, Spielbauer G, Tseung CW, Siebert AE, Barbazuk WB, Lal S, Settles AM. Bai F, et al. Plant Cell. 2019 Mar;31(3):715-733. doi: 10.1105/tpc.18.00754. Epub 2019 Feb 13. Plant Cell. 2019. PMID: 30760564 Free PMC article.
Protein-protein interactions between RBM48, RGH3, and U2 Auxiliary Factor (U2AF) subunits suggest major and minor spliceosome factors required for intron recognition form complexes with RBM48. Human RBM48 interacts with armadillo repeat containing 7 (ARMC7). Maize RBM48 an …
Protein-protein interactions between RBM48, RGH3, and U2 Auxiliary Factor (U2AF) subunits suggest major and minor spliceosome factors requir …
A novel lncRNA-mRNA-miRNA signature predicts recurrence and disease-free survival in cervical cancer.
Li M, Tian X, Guo H, Xu X, Liu Y, Hao X, Fei H. Li M, et al. Braz J Med Biol Res. 2021 Sep 20;54(11):e11592. doi: 10.1590/1414-431X2021e11592. eCollection 2021. Braz J Med Biol Res. 2021. PMID: 34550275 Free PMC article.
A prognostic signature, containing two DELs (CD27-AS1, LINC00683), three DEMis (hsa-miR-146b, hsa-miR-1238, hsa-miR-4648), and seven DEMs (ARMC7, ATRX, FBLN5, GHR, MYLIP, OXCT1, RAB39A), was developed after LASSO analysis. ...
A prognostic signature, containing two DELs (CD27-AS1, LINC00683), three DEMis (hsa-miR-146b, hsa-miR-1238, hsa-miR-4648), and seven DEMs ( …
Gene biomarker discovery at different stages of Alzheimer using gene co-expression network approach.
Soleimani Zakeri NS, Pashazadeh S, MotieGhader H. Soleimani Zakeri NS, et al. Sci Rep. 2020 Jul 22;10(1):12210. doi: 10.1038/s41598-020-69249-8. Sci Rep. 2020. PMID: 32699331 Free PMC article.
The outcomes addressed proposed novel genes, including MBOAT1, ARMC7, RABL2B, HNRNPUL1, LAMTOR1, PLAGL2, CREBRF, LCOR, and MRI1and novel miRNAs comprising miR-615-3p, miR-4722-5p, miR-4768-3p, miR-1827, miR-940 and miR-30b-3p which were related to AD. ...
The outcomes addressed proposed novel genes, including MBOAT1, ARMC7, RABL2B, HNRNPUL1, LAMTOR1, PLAGL2, CREBRF, LCOR, and MRI1and no …
[Whole-genome association studies of distribution of developmental abnormalities and other breeding-valuable qualitative traits in offspring of the Russian large-white boars].
Траспов АА, Костюнина ОВ, Белоус АА, Карпушкина ТВ, Свеженцева НА, Зиновьева НА. Траспов АА, et al. Vavilovskii Zhurnal Genet Selektsii. 2020 Mar;24(2):185-190. doi: 10.18699/VJ20.612. Vavilovskii Zhurnal Genet Selektsii. 2020. PMID: 33659798 Free PMC article. Russian.

After GWAS, we obtained 24 alleles in 11 corresponding genes (P < 0.1) in the genome of pigs, which are significantly correlated with traits of developmental abnormalities such as anal atresia (ARMC7, FANCC, RND3, ENSSSCG00000017216), limb problems (PAWR, NTM, OPCML, EN

After GWAS, we obtained 24 alleles in 11 corresponding genes (P < 0.1) in the genome of pigs, which are significantly correlated with tra