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Endoglin has a crucial role in blood cell-mediated vascular repair.
van Laake LW, van den Driesche S, Post S, Feijen A, Jansen MA, Driessens MH, Mager JJ, Snijder RJ, Westermann CJ, Doevendans PA, van Echteld CJ, ten Dijke P, Arthur HM, Goumans MJ, Lebrin F, Mummery CL. van Laake LW, et al. Among authors: arthur hm. Circulation. 2006 Nov 21;114(21):2288-97. doi: 10.1161/CIRCULATIONAHA.106.639161. Epub 2006 Nov 6. Circulation. 2006. PMID: 17088457
Generation of a floxed allele of the mouse Endoglin gene.
Allinson KR, Carvalho RL, van den Brink S, Mummery CL, Arthur HM. Allinson KR, et al. Among authors: arthur hm. Genesis. 2007 Jun;45(6):391-5. doi: 10.1002/dvg.20284. Genesis. 2007. PMID: 17506087 Free PMC article.
Thalidomide stimulates vessel maturation and reduces epistaxis in individuals with hereditary hemorrhagic telangiectasia.
Lebrin F, Srun S, Raymond K, Martin S, van den Brink S, Freitas C, Bréant C, Mathivet T, Larrivée B, Thomas JL, Arthur HM, Westermann CJ, Disch F, Mager JJ, Snijder RJ, Eichmann A, Mummery CL. Lebrin F, et al. Among authors: arthur hm. Nat Med. 2010 Apr;16(4):420-8. doi: 10.1038/nm.2131. Epub 2010 Apr 4. Nat Med. 2010. PMID: 20364125
Deficiency for endoglin in tumor vasculature weakens the endothelial barrier to metastatic dissemination.
Anderberg C, Cunha SI, Zhai Z, Cortez E, Pardali E, Johnson JR, Franco M, Páez-Ribes M, Cordiner R, Fuxe J, Johansson BR, Goumans MJ, Casanovas O, ten Dijke P, Arthur HM, Pietras K. Anderberg C, et al. Among authors: arthur hm. J Exp Med. 2013 Mar 11;210(3):563-79. doi: 10.1084/jem.20120662. Epub 2013 Feb 11. J Exp Med. 2013. PMID: 23401487 Free PMC article.
ENDOGLIN is dispensable for vasculogenesis, but required for vascular endothelial growth factor-induced angiogenesis.
Liu Z, Lebrin F, Maring JA, van den Driesche S, van der Brink S, van Dinther M, Thorikay M, Martin S, Kobayashi K, Hawinkels LJ, van Meeteren LA, Pardali E, Korving J, Letarte M, Arthur HM, Theuer C, Goumans MJ, Mummery C, ten Dijke P. Liu Z, et al. Among authors: arthur hm. PLoS One. 2014 Jan 28;9(1):e86273. doi: 10.1371/journal.pone.0086273. eCollection 2014. PLoS One. 2014. PMID: 24489709 Free PMC article.
Interaction Between ALK1 Signaling and Connexin40 in the Development of Arteriovenous Malformations.
Gkatzis K, Thalgott J, Dos-Santos-Luis D, Martin S, Lamandé N, Carette MF, Disch F, Snijder RJ, Westermann CJ, Mager JJ, Oh SP, Miquerol L, Arthur HM, Mummery CL, Lebrin F. Gkatzis K, et al. Among authors: arthur hm. Arterioscler Thromb Vasc Biol. 2016 Apr;36(4):707-17. doi: 10.1161/ATVBAHA.115.306719. Epub 2016 Jan 28. Arterioscler Thromb Vasc Biol. 2016. PMID: 26821948
165 results