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Ablation of C/EBPbeta alleviates ER stress and pancreatic beta cell failure through the GRP78 chaperone in mice.
Matsuda T, Kido Y, Asahara S, Kaisho T, Tanaka T, Hashimoto N, Shigeyama Y, Takeda A, Inoue T, Shibutani Y, Koyanagi M, Hosooka T, Matsumoto M, Inoue H, Uchida T, Koike M, Uchiyama Y, Akira S, Kasuga M. Matsuda T, et al. Among authors: asahara s. J Clin Invest. 2010 Jan;120(1):115-26. doi: 10.1172/JCI39721. Epub 2009 Dec 1. J Clin Invest. 2010. PMID: 19955657 Free PMC article.
Ablation of TSC2 enhances insulin secretion by increasing the number of mitochondria through activation of mTORC1.
Koyanagi M, Asahara S, Matsuda T, Hashimoto N, Shigeyama Y, Shibutani Y, Kanno A, Fuchita M, Mikami T, Hosooka T, Inoue H, Matsumoto M, Koike M, Uchiyama Y, Noda T, Seino S, Kasuga M, Kido Y. Koyanagi M, et al. Among authors: asahara s. PLoS One. 2011;6(8):e23238. doi: 10.1371/journal.pone.0023238. Epub 2011 Aug 19. PLoS One. 2011. PMID: 21886784 Free PMC article.
DPP4 inhibitor vildagliptin preserves β-cell mass through amelioration of endoplasmic reticulum stress in C/EBPB transgenic mice.
Shimizu S, Hosooka T, Matsuda T, Asahara S, Koyanagi-Kimura M, Kanno A, Bartolome A, Etoh H, Fuchita M, Teruyama K, Takahashi H, Inoue H, Mieda Y, Hashimoto N, Seino S, Kido Y. Shimizu S, et al. Among authors: asahara s. J Mol Endocrinol. 2012 Aug 30;49(2):125-35. doi: 10.1530/JME-12-0039. Print 2012 Oct. J Mol Endocrinol. 2012. PMID: 22822047
Ras-related C3 botulinum toxin substrate 1 (RAC1) regulates glucose-stimulated insulin secretion via modulation of F-actin.
Asahara S, Shibutani Y, Teruyama K, Inoue HY, Kawada Y, Etoh H, Matsuda T, Kimura-Koyanagi M, Hashimoto N, Sakahara M, Fujimoto W, Takahashi H, Ueda S, Hosooka T, Satoh T, Inoue H, Matsumoto M, Aiba A, Kasuga M, Kido Y. Asahara S, et al. Diabetologia. 2013 May;56(5):1088-97. doi: 10.1007/s00125-013-2849-5. Epub 2013 Feb 15. Diabetologia. 2013. PMID: 23412604 Free PMC article.
Histidine augments the suppression of hepatic glucose production by central insulin action.
Kimura K, Nakamura Y, Inaba Y, Matsumoto M, Kido Y, Asahara S, Matsuda T, Watanabe H, Maeda A, Inagaki F, Mukai C, Takeda K, Akira S, Ota T, Nakabayashi H, Kaneko S, Kasuga M, Inoue H. Kimura K, et al. Among authors: asahara s. Diabetes. 2013 Jul;62(7):2266-77. doi: 10.2337/db12-1701. Epub 2013 Mar 8. Diabetes. 2013. PMID: 23474485 Free PMC article.
87 results