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[Metabolism-dependent Vascular Pathophysiology in Adult Diseases].
Kushiyama A, Takahashi M, Kushiyama S, Kikuchi T, Asano T. Kushiyama A, et al. Among authors: asano t. Yakugaku Zasshi. 2022;142(5):465-471. doi: 10.1248/yakushi.21-00176-3. Yakugaku Zasshi. 2022. PMID: 35491150 Free article. Japanese.
Xanthine oxidoreductase is involved in macrophage foam cell formation and atherosclerosis development.
Kushiyama A, Okubo H, Sakoda H, Kikuchi T, Fujishiro M, Sato H, Kushiyama S, Iwashita M, Nishimura F, Fukushima T, Nakatsu Y, Kamata H, Kawazu S, Higashi Y, Kurihara H, Asano T. Kushiyama A, et al. Among authors: asano t. Arterioscler Thromb Vasc Biol. 2012 Feb;32(2):291-8. doi: 10.1161/ATVBAHA.111.234559. Epub 2011 Nov 17. Arterioscler Thromb Vasc Biol. 2012. PMID: 22095983
Resistin-like molecule β is abundantly expressed in foam cells and is involved in atherosclerosis development.
Kushiyama A, Sakoda H, Oue N, Okubo M, Nakatsu Y, Ono H, Fukushima T, Kamata H, Nishimura F, Kikuchi T, Fujishiro M, Nishiyama K, Aburatani H, Kushiyama S, Iizuka M, Taki N, Encinas J, Sentani K, Ogonuki N, Ogura A, Kawazu S, Yasui W, Higashi Y, Kurihara H, Katagiri H, Asano T. Kushiyama A, et al. Among authors: asano t. Arterioscler Thromb Vasc Biol. 2013 Aug;33(8):1986-93. doi: 10.1161/ATVBAHA.113.301546. Epub 2013 May 23. Arterioscler Thromb Vasc Biol. 2013. PMID: 23702657
The xanthine oxidase inhibitor febuxostat suppresses development of nonalcoholic steatohepatitis in a rodent model.
Nakatsu Y, Seno Y, Kushiyama A, Sakoda H, Fujishiro M, Katasako A, Mori K, Matsunaga Y, Fukushima T, Kanaoka R, Yamamotoya T, Kamata H, Asano T. Nakatsu Y, et al. Among authors: asano t. Am J Physiol Gastrointest Liver Physiol. 2015 Jul 1;309(1):G42-51. doi: 10.1152/ajpgi.00443.2014. Epub 2015 May 21. Am J Physiol Gastrointest Liver Physiol. 2015. PMID: 25999428 Free article.
Involvement of resistin-like molecule β in the development of methionine-choline deficient diet-induced non-alcoholic steatohepatitis in mice.
Okubo H, Kushiyama A, Sakoda H, Nakatsu Y, Iizuka M, Taki N, Fujishiro M, Fukushima T, Kamata H, Nagamachi A, Inaba T, Nishimura F, Katagiri H, Asahara T, Yoshida Y, Chonan O, Encinas J, Asano T. Okubo H, et al. Among authors: asano t. Sci Rep. 2016 Jan 28;6:20157. doi: 10.1038/srep20157. Sci Rep. 2016. PMID: 26818807 Free PMC article.
Role of Uric Acid Metabolism-Related Inflammation in the Pathogenesis of Metabolic Syndrome Components Such as Atherosclerosis and Nonalcoholic Steatohepatitis.
Kushiyama A, Nakatsu Y, Matsunaga Y, Yamamotoya T, Mori K, Ueda K, Inoue Y, Sakoda H, Fujishiro M, Ono H, Asano T. Kushiyama A, et al. Among authors: asano t. Mediators Inflamm. 2016;2016:8603164. doi: 10.1155/2016/8603164. Epub 2016 Dec 14. Mediators Inflamm. 2016. PMID: 28070145 Free PMC article. Review.
The SGLT2 Inhibitor Luseogliflozin Rapidly Normalizes Aortic mRNA Levels of Inflammation-Related but Not Lipid-Metabolism-Related Genes and Suppresses Atherosclerosis in Diabetic ApoE KO Mice.
Nakatsu Y, Kokubo H, Bumdelger B, Yoshizumi M, Yamamotoya T, Matsunaga Y, Ueda K, Inoue Y, Inoue MK, Fujishiro M, Kushiyama A, Ono H, Sakoda H, Asano T. Nakatsu Y, et al. Among authors: asano t. Int J Mol Sci. 2017 Aug 4;18(8):1704. doi: 10.3390/ijms18081704. Int J Mol Sci. 2017. PMID: 28777298 Free PMC article.
Gut Microbiota as a Therapeutic Target for Metabolic Disorders.
Okubo H, Nakatsu Y, Kushiyama A, Yamamotoya T, Matsunaga Y, Inoue MK, Fujishiro M, Sakoda H, Ohno H, Yoneda M, Ono H, Asano T. Okubo H, et al. Among authors: asano t. Curr Med Chem. 2018;25(9):984-1001. doi: 10.2174/0929867324666171009121702. Curr Med Chem. 2018. PMID: 28990516 Review.
2,910 results