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Brain immunology and immunotherapy in brain tumours.
Sampson JH, Gunn MD, Fecci PE, Ashley DM. Sampson JH, et al. Among authors: ashley dm. Nat Rev Cancer. 2020 Jan;20(1):12-25. doi: 10.1038/s41568-019-0224-7. Epub 2019 Dec 5. Nat Rev Cancer. 2020. PMID: 31806885 Free PMC article. Review.
Salting the Soil: Targeting the Microenvironment of Brain Metastases.
Srinivasan ES, Tan AC, Anders CK, Pendergast AM, Sipkins DA, Ashley DM, Fecci PE, Khasraw M. Srinivasan ES, et al. Among authors: ashley dm. Mol Cancer Ther. 2021 Mar;20(3):455-466. doi: 10.1158/1535-7163.MCT-20-0579. Epub 2021 Jan 5. Mol Cancer Ther. 2021. PMID: 33402399 Free PMC article. Review.
Very low mutation burden is a feature of inflamed recurrent glioblastomas responsive to cancer immunotherapy.
Gromeier M, Brown MC, Zhang G, Lin X, Chen Y, Wei Z, Beaubier N, Yan H, He Y, Desjardins A, Herndon JE 2nd, Varn FS, Verhaak RG, Zhao J, Bolognesi DP, Friedman AH, Friedman HS, McSherry F, Muscat AM, Lipp ES, Nair SK, Khasraw M, Peters KB, Randazzo D, Sampson JH, McLendon RE, Bigner DD, Ashley DM. Gromeier M, et al. Among authors: ashley dm. Nat Commun. 2021 Jan 13;12(1):352. doi: 10.1038/s41467-020-20469-6. Nat Commun. 2021. PMID: 33441554 Free PMC article.
Designing Clinical Trials for Combination Immunotherapy: A Framework for Glioblastoma.
Singh K, Batich KA, Wen PY, Tan AC, Bagley SJ, Lim M, Platten M, Colman H, Ashley DM, Chang SM, Rahman R, Galanis E, Mansouri A, Puduvalli VK, Reardon DA, Sahebjam S, Sampson JH, Simes J, Berry DA, Zadeh G, Cloughesy TF, Mehta MP, Piantadosi S, Weller M, Heimberger AB, Khasraw M. Singh K, et al. Among authors: ashley dm. Clin Cancer Res. 2022 Feb 15;28(4):585-593. doi: 10.1158/1078-0432.CCR-21-2681. Clin Cancer Res. 2022. PMID: 34561270 Free PMC article. Review.
Unarmed, tumor-specific monoclonal antibody effectively treats brain tumors.
Sampson JH, Crotty LE, Lee S, Archer GE, Ashley DM, Wikstrand CJ, Hale LP, Small C, Dranoff G, Friedman AH, Friedman HS, Bigner DD. Sampson JH, et al. Among authors: ashley dm. Proc Natl Acad Sci U S A. 2000 Jun 20;97(13):7503-8. doi: 10.1073/pnas.130166597. Proc Natl Acad Sci U S A. 2000. PMID: 10852962 Free PMC article.
Subcutaneous vaccination with irradiated, cytokine-producing tumor cells stimulates CD8+ cell-mediated immunity against tumors located in the "immunologically privileged" central nervous system.
Sampson JH, Archer GE, Ashley DM, Fuchs HE, Hale LP, Dranoff G, Bigner DD. Sampson JH, et al. Among authors: ashley dm. Proc Natl Acad Sci U S A. 1996 Sep 17;93(19):10399-404. doi: 10.1073/pnas.93.19.10399. Proc Natl Acad Sci U S A. 1996. PMID: 8816812 Free PMC article.
Low tumor mutational burden and immunotherapy in gliomas.
Brown MC, Ashley DM, Khasraw M. Brown MC, et al. Among authors: ashley dm. Trends Cancer. 2022 May;8(5):345-346. doi: 10.1016/j.trecan.2022.01.006. Epub 2022 Jan 31. Trends Cancer. 2022. PMID: 35093301 No abstract available.
168 results