Ashton NW - Search Results

1

A structural analysis of DNA binding by hSSB1 (NABP2/OBFC2B) in solution.

Touma C, Kariawasam R, Gimenez AX, Bernardo RE, Ashton NW, Adams MN, Paquet N, Croll TI, O'Byrne KJ, Richard DJ, Cubeddu L, Gamsjaeger R. Touma C, et al. Among authors: ashton nw. Nucleic Acids Res. 2016 Sep 19;44(16):7963-73. doi: 10.1093/nar/gkw617. Epub 2016 Jul 7. Nucleic Acids Res. 2016. PMID: 27387285 Free PMC article.

2

Human single-stranded DNA binding proteins are essential for maintaining genomic stability.

Ashton NW, Bolderson E, Cubeddu L, O'Byrne KJ, Richard DJ. Ashton NW, et al. BMC Mol Biol. 2013 Apr 1;14:9. doi: 10.1186/1471-2199-14-9. BMC Mol Biol. 2013. PMID: 23548139 Free PMC article. Review.

3

Néstor-Guillermo Progeria Syndrome: a biochemical insight into Barrier-to-Autointegration Factor 1, alanine 12 threonine mutation.

Paquet N, Box JK, Ashton NW, Suraweera A, Croft LV, Urquhart AJ, Bolderson E, Zhang SD, O'Byrne KJ, Richard DJ. Paquet N, et al. Among authors: ashton nw. BMC Mol Biol. 2014 Dec 12;15:27. doi: 10.1186/s12867-014-0027-z. BMC Mol Biol. 2014. PMID: 25495845 Free PMC article.

4

hSSB1 (NABP2/ OBFC2B) is required for the repair of 8-oxo-guanine by the hOGG1-mediated base excision repair pathway.

Paquet N, Adams MN, Leong V, Ashton NW, Touma C, Gamsjaeger R, Cubeddu L, Beard S, Burgess JT, Bolderson E, O'Byrne KJ, Richard DJ. Paquet N, et al. Among authors: ashton nw. Nucleic Acids Res. 2015 Oct 15;43(18):8817-29. doi: 10.1093/nar/gkv790. Epub 2015 Aug 10. Nucleic Acids Res. 2015. PMID: 26261212 Free PMC article.

5

hSSB1 (NABP2/OBFC2B) is regulated by oxidative stress.

Paquet N, Adams MN, Ashton NW, Touma C, Gamsjaeger R, Cubeddu L, Leong V, Beard S, Bolderson E, Botting CH, O'Byrne KJ, Richard DJ. Paquet N, et al. Among authors: ashton nw. Sci Rep. 2016 Jun 8;6:27446. doi: 10.1038/srep27446. Sci Rep. 2016. PMID: 27273218 Free PMC article.

6

Novel insight into the composition of human single-stranded DNA-binding protein 1 (hSSB1)-containing protein complexes.

Ashton NW, Loo D, Paquet N, O'Byrne KJ, Richard DJ. Ashton NW, et al. BMC Mol Biol. 2016 Dec 9;17(1):24. doi: 10.1186/s12867-016-0077-5. BMC Mol Biol. 2016. PMID: 27938330 Free PMC article.

7

hSSB1 phosphorylation is dynamically regulated by DNA-PK and PPP-family protein phosphatases.

Ashton NW, Paquet N, Shirran SL, Bolderson E, Kariawasam R, Touma C, Fallahbaghery A, Gamsjaeger R, Cubeddu L, Botting C, Pollock PM, O'Byrne KJ, Richard DJ. Ashton NW, et al. DNA Repair (Amst). 2017 Jun;54:30-39. doi: 10.1016/j.dnarep.2017.03.006. Epub 2017 Apr 6. DNA Repair (Amst). 2017. PMID: 28448822 Free article.

8

hSSB1 associates with and promotes stability of the BLM helicase.

Croft LV, Ashton NW, Paquet N, Bolderson E, O'Byrne KJ, Richard DJ. Croft LV, et al. Among authors: ashton nw. BMC Mol Biol. 2017 May 15;18(1):13. doi: 10.1186/s12867-017-0090-3. BMC Mol Biol. 2017. PMID: 28506294 Free PMC article.

9

A data-driven structural model of hSSB1 (NABP2/OBFC2B) self-oligomerization.

Touma C, Adams MN, Ashton NW, Mizzi M, El-Kamand S, Richard DJ, Cubeddu L, Gamsjaeger R. Touma C, et al. Among authors: ashton nw. Nucleic Acids Res. 2017 Aug 21;45(14):8609-8620. doi: 10.1093/nar/gkx526. Nucleic Acids Res. 2017. PMID: 28609781 Free PMC article.

10

COMMD4 functions with the histone H2A-H2B dimer for the timely repair of DNA double-strand breaks.

Suraweera A, Gandhi NS, Beard S, Burgess JT, Croft LV, Bolderson E, Naqi A, Ashton NW, Adams MN, Savage KI, Zhang SD, O'Byrne KJ, Richard DJ. Suraweera A, et al. Among authors: ashton nw. Commun Biol. 2021 Apr 19;4(1):484. doi: 10.1038/s42003-021-01998-2. Commun Biol. 2021. PMID: 33875784 Free PMC article.

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