Molecular mechanism of anti-SARS-CoV2 activity of Ashwagandha-derived withanolides.
Dhanjal JK, Kumar V, Garg S, Subramani C, Agarwal S, Wang J, Zhang H, Kaul A, Kalra RS, Kaul SC, Vrati S, Sundar D, Wadhwa R.
Dhanjal JK, et al.
Int J Biol Macromol. 2021 Aug 1;184:297-312. doi: 10.1016/j.ijbiomac.2021.06.015. Epub 2021 Jun 9.
Int J Biol Macromol. 2021.
PMID: 34118289
Free PMC article.
Here, we have investigated the therapeutic prospective of Ashwagandha for the COVID-19 pandemic. Nine withanolides were tested in silico for their potential to target and inhibit (i) cell surface receptor protein (TMPRSS2) that is required for entry of virus to host cells …
Here, we have investigated the therapeutic prospective of Ashwagandha for the COVID-19 pandemic. Nine withanolides were tested in sil …