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Nootropic potential of Ashwagandha leaves: Beyond traditional root extracts.
Wadhwa R, Konar A, Kaul SC. Wadhwa R, et al. Neurochem Int. 2016 May;95:109-18. doi: 10.1016/j.neuint.2015.09.001. Epub 2015 Sep 8. Neurochem Int. 2016. PMID: 26361721 Review.
However, active principles and underlying mechanism(s) of action remain largely unknown. Here we provide a review on the effects of Ashwagandha extracts and active principles, and underlying molecular mechanism(s) for brain pathologies. We highlight our findings on the noo …
However, active principles and underlying mechanism(s) of action remain largely unknown. Here we provide a review on the effects of Ashwa
Effect of Ashwagandha Withanolides on Muscle Cell Differentiation.
Wang J, Zhang H, Kaul A, Li K, Priyandoko D, Kaul SC, Wadhwa R. Wang J, et al. Biomolecules. 2021 Oct 4;11(10):1454. doi: 10.3390/biom11101454. Biomolecules. 2021. PMID: 34680087 Free PMC article.
Withania somnifera (Ashwagandha) is used in Indian traditional medicine, Ayurveda, and is believed to have a variety of health-promoting effects. ...We found that withaferin A and withanone and Ashwagandha extracts possessing different ratios of these active
Withania somnifera (Ashwagandha) is used in Indian traditional medicine, Ayurveda, and is believed to have a variety of health
Molecular mechanism of anti-SARS-CoV2 activity of Ashwagandha-derived withanolides.
Dhanjal JK, Kumar V, Garg S, Subramani C, Agarwal S, Wang J, Zhang H, Kaul A, Kalra RS, Kaul SC, Vrati S, Sundar D, Wadhwa R. Dhanjal JK, et al. Int J Biol Macromol. 2021 Aug 1;184:297-312. doi: 10.1016/j.ijbiomac.2021.06.015. Epub 2021 Jun 9. Int J Biol Macromol. 2021. PMID: 34118289 Free PMC article.
Here, we have investigated the therapeutic prospective of Ashwagandha for the COVID-19 pandemic. Nine withanolides were tested in silico for their potential to target and inhibit (i) cell surface receptor protein (TMPRSS2) that is required for entry of virus to host cells …
Here, we have investigated the therapeutic prospective of Ashwagandha for the COVID-19 pandemic. Nine withanolides were tested in sil …
Biotechnological interventions in Withania somnifera (L.) Dunal.
Singh P, Guleri R, Singh V, Kaur G, Kataria H, Singh B, Kaur G, Kaul SC, Wadhwa R, Pati PK. Singh P, et al. Biotechnol Genet Eng Rev. 2015 Apr-Oct;31(1-2):1-20. doi: 10.1080/02648725.2015.1020467. Epub 2015 Mar 19. Biotechnol Genet Eng Rev. 2015. PMID: 25787309 Review.
Withania somnifera is one of the most valued plants and is extensively used in Indian, Unani, and African systems of traditional medicine. ...
Withania somnifera is one of the most valued plants and is extensively used in Indian, Unani, and African systems of traditional medi
Experimental evidence and mechanism of action of some popular neuro-nutraceutical herbs.
Kumar A, Konar A, Garg S, Kaul SC, Wadhwa R. Kumar A, et al. Neurochem Int. 2021 Oct;149:105124. doi: 10.1016/j.neuint.2021.105124. Epub 2021 Jul 7. Neurochem Int. 2021. PMID: 34245808 Review.
The present review highlights the identification, experimental evidence and applications of some herbs including Bacopa monniera, Withania somnifera, Curcuma longa, Helicteres angustifolia, Undaria pinnatifida, Haematococcus pluvialis, and Vitis vinifera, as neuro-nutraceu …
The present review highlights the identification, experimental evidence and applications of some herbs including Bacopa monniera, Withani
Novel Methods to Generate Active Ingredients-Enriched Ashwagandha Leaves and Extracts.
Kaul SC, Ishida Y, Tamura K, Wada T, Iitsuka T, Garg S, Kim M, Gao R, Nakai S, Okamoto Y, Terao K, Wadhwa R. Kaul SC, et al. PLoS One. 2016 Dec 9;11(12):e0166945. doi: 10.1371/journal.pone.0166945. eCollection 2016. PLoS One. 2016. PMID: 27936030 Free PMC article.
Ashwagandha (Withania somnifera) is an Ayurvedic herb commonly used in world-renowned traditional Indian home medicine system. Roots of Ashwagandha have been traditionally known to possess a variety of therapeutic and health promoting potentials that have not
Ashwagandha (Withania somnifera) is an Ayurvedic herb commonly used in world-renowned traditional Indian home medicine system.
Assessment of Cholinergic Properties of Ashwagandha Leaf-Extract in the Amnesic Mouse Brain.
Gautam A, Wadhwa R, Thakur MK. Gautam A, et al. Ann Neurosci. 2016 Jul;23(2):68-75. doi: 10.1159/000443573. Epub 2016 Jul 7. Ann Neurosci. 2016. PMID: 27647956 Free PMC article.
PURPOSE: However, the exact mechanism through which Ashwagandha demonstrates these effects is still unknown. METHODS: In the present study, we hypothesized that the alcoholic extract of Ashwagandha leaves (i-Extract) possesses cholinergic properties, which in turn i …
PURPOSE: However, the exact mechanism through which Ashwagandha demonstrates these effects is still unknown. METHODS: In the present …
Withanone-rich combination of Ashwagandha withanolides restricts metastasis and angiogenesis through hnRNP-K.
Gao R, Shah N, Lee JS, Katiyar SP, Li L, Oh E, Sundar D, Yun CO, Wadhwa R, Kaul SC. Gao R, et al. Mol Cancer Ther. 2014 Dec;13(12):2930-40. doi: 10.1158/1535-7163.MCT-14-0324. Epub 2014 Sep 18. Mol Cancer Ther. 2014. PMID: 25236891
Ashwagandha is an important herb used in the Indian system of traditional home medicine, Ayurveda. ...
Ashwagandha is an important herb used in the Indian system of traditional home medicine, Ayurveda. ...
Triethylene glycol, an active component of Ashwagandha (Withania somnifera) leaves, is responsible for sleep induction.
Kaushik MK, Kaul SC, Wadhwa R, Yanagisawa M, Urade Y. Kaushik MK, et al. PLoS One. 2017 Feb 16;12(2):e0172508. doi: 10.1371/journal.pone.0172508. eCollection 2017. PLoS One. 2017. PMID: 28207892 Free PMC article.
Hence natural therapies could be an alternative choice of treatment for insomnia. The root or whole plant extract of Ashwagandha (Withania somnifera) has been used to induce sleep in Indian system of traditional home medicine, Ayurveda. ...These results clearly demo …
Hence natural therapies could be an alternative choice of treatment for insomnia. The root or whole plant extract of Ashwagandha ( …
Combinations of Ashwagandha leaf extracts protect brain-derived cells against oxidative stress and induce differentiation.
Shah N, Singh R, Sarangi U, Saxena N, Chaudhary A, Kaur G, Kaul SC, Wadhwa R. Shah N, et al. PLoS One. 2015 Mar 19;10(3):e0120554. doi: 10.1371/journal.pone.0120554. eCollection 2015. PLoS One. 2015. PMID: 25789768 Free PMC article.
BACKGROUND: Ashwagandha, a traditional Indian herb, has been known for its variety of therapeutic activities. ...Furthermore, the combinations of extracts and active component were highly potent endorsing the therapeutic merit of the combinational approach. CONCLUSION: …
BACKGROUND: Ashwagandha, a traditional Indian herb, has been known for its variety of therapeutic activities. ...Furthermore, the com …
49 results