Askew C - Search Results

1

Matrix metalloproteinase dysregulation in the stria vascularis of mice with Alport syndrome: implications for capillary basement membrane pathology.

Gratton MA, Rao VH, Meehan DT, Askew C, Cosgrove D. Gratton MA, et al. Among authors: askew c. Am J Pathol. 2005 May;166(5):1465-74. doi: 10.1016/S0002-9440(10)62363-2. Am J Pathol. 2005. PMID: 15855646 Free PMC article.

2

Localization and expression of clarin-1, the Clrn1 gene product, in auditory hair cells and photoreceptors.

Zallocchi M, Meehan DT, Delimont D, Askew C, Garige S, Gratton MA, Rothermund-Franklin CA, Cosgrove D. Zallocchi M, et al. Among authors: askew c. Hear Res. 2009 Sep;255(1-2):109-20. doi: 10.1016/j.heares.2009.06.006. Epub 2009 Jun 16. Hear Res. 2009. PMID: 19539019 Free PMC article.

3

The mechanosensory structure of the hair cell requires clarin-1, a protein encoded by Usher syndrome III causative gene.

Geng R, Melki S, Chen DH, Tian G, Furness DN, Oshima-Takago T, Neef J, Moser T, Askew C, Horwitz G, Holt JR, Imanishi Y, Alagramam KN. Geng R, et al. Among authors: askew c. J Neurosci. 2012 Jul 11;32(28):9485-98. doi: 10.1523/JNEUROSCI.0311-12.2012. J Neurosci. 2012. PMID: 22787034 Free PMC article.

4

Deletion of PDZD7 disrupts the Usher syndrome type 2 protein complex in cochlear hair cells and causes hearing loss in mice.

Zou J, Zheng T, Ren C, Askew C, Liu XP, Pan B, Holt JR, Wang Y, Yang J. Zou J, et al. Among authors: askew c. Hum Mol Genet. 2014 May 1;23(9):2374-90. doi: 10.1093/hmg/ddt629. Epub 2013 Dec 11. Hum Mol Genet. 2014. PMID: 24334608 Free PMC article.

5

Gene therapy restores auditory and vestibular function in a mouse model of Usher syndrome type 1c.

Pan B, Askew C, Galvin A, Heman-Ackah S, Asai Y, Indzhykulian AA, Jodelka FM, Hastings ML, Lentz JJ, Vandenberghe LH, Holt JR, Géléoc GS. Pan B, et al. Among authors: askew c. Nat Biotechnol. 2017 Mar;35(3):264-272. doi: 10.1038/nbt.3801. Epub 2017 Feb 6. Nat Biotechnol. 2017. PMID: 28165476 Free PMC article.

6

A synthetic AAV vector enables safe and efficient gene transfer to the mammalian inner ear.

Landegger LD, Pan B, Askew C, Wassmer SJ, Gluck SD, Galvin A, Taylor R, Forge A, Stankovic KM, Holt JR, Vandenberghe LH. Landegger LD, et al. Among authors: askew c. Nat Biotechnol. 2017 Mar;35(3):280-284. doi: 10.1038/nbt.3781. Epub 2017 Feb 6. Nat Biotechnol. 2017. PMID: 28165475 Free PMC article.

7

Tmc gene therapy restores auditory function in deaf mice.

Askew C, Rochat C, Pan B, Asai Y, Ahmed H, Child E, Schneider BL, Aebischer P, Holt JR. Askew C, et al. Sci Transl Med. 2015 Jul 8;7(295):295ra108. doi: 10.1126/scitranslmed.aab1996. Sci Transl Med. 2015. PMID: 26157030 Free PMC article.

8

Hair cell and neural contributions to the cochlear summating potential.

Pappa AK, Hutson KA, Scott WC, Wilson JD, Fox KE, Masood MM, Giardina CK, Pulver SH, Grana GD, Askew C, Fitzpatrick DC. Pappa AK, et al. Among authors: askew c. J Neurophysiol. 2019 Jun 1;121(6):2163-2180. doi: 10.1152/jn.00006.2019. Epub 2019 Apr 3. J Neurophysiol. 2019. PMID: 30943095 Free PMC article.

9

Self-complementarity in adeno-associated virus enhances transduction and gene expression in mouse cochlear tissues.

Casey G, Askew C, Brimble MA, Samulski RJ, Davidoff AM, Li C, Walters BJ. Casey G, et al. Among authors: askew c. PLoS One. 2020 Nov 23;15(11):e0242599. doi: 10.1371/journal.pone.0242599. eCollection 2020. PLoS One. 2020. PMID: 33227033 Free PMC article.

10

Adeno-associated virus gene replacement for recessive inner ear dysfunction: Progress and challenges.

Askew C, Chien WW. Askew C, et al. Hear Res. 2020 Sep 1;394:107947. doi: 10.1016/j.heares.2020.107947. Epub 2020 Mar 18. Hear Res. 2020. PMID: 32247629 Free PMC article. Review.

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