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Page 1
Discovery of a potent nicotinic Acid receptor agonist for the treatment of dyslipidemia.
Qin J, Rao A, Chen X, Zhu X, Liu Z, Huang X, Degrado S, Huang Y, Xiao D, Aslanian R, Cheewatrakoolpong B, Zhang H, Greenfeder S, Farley C, Cook J, Kurowski S, Li Q, van Heek M, Chintala M, Wang G, Hsieh Y, Li F, Palani A. Qin J, et al. Among authors: aslanian r. ACS Med Chem Lett. 2010 Dec 8;2(2):171-6. doi: 10.1021/ml100251u. eCollection 2011 Feb 10. ACS Med Chem Lett. 2010. PMID: 24900295 Free PMC article.
SAR studies of C2 ethers of 2H-pyrano[2,3-d]pyrimidine-2,4,7(1H,3H)-triones as nicotinic acid receptor (NAR) agonist.
Huang X, Su J, Rao AU, Tang H, Zhou W, Zhu X, Chen X, Liu Z, Huang Y, Degrado S, Xiao D, Qin J, Aslanian R, McKittrick BA, Greenfeder S, Heek Mv, Chintala M, Palani A. Huang X, et al. Among authors: aslanian r. Bioorg Med Chem Lett. 2012 Jan 15;22(2):854-8. doi: 10.1016/j.bmcl.2011.12.041. Epub 2011 Dec 13. Bioorg Med Chem Lett. 2012. PMID: 22209457
Discovery of SCH 900271, a Potent Nicotinic Acid Receptor Agonist for the Treatment of Dyslipidemia.
Palani A, Rao AU, Chen X, Huang X, Su J, Tang H, Huang Y, Qin J, Xiao D, Degrado S, Sofolarides M, Zhu X, Liu Z, McKittrick B, Zhou W, Aslanian R, Greenlee WJ, Senior M, Cheewatrakoolpong B, Zhang H, Farley C, Cook J, Kurowski S, Li Q, van Heek M, Wang G, Hsieh Y, Li F, Greenfeder S, Chintala M. Palani A, et al. Among authors: aslanian r. ACS Med Chem Lett. 2011 Nov 24;3(1):63-8. doi: 10.1021/ml200243g. eCollection 2012 Jan 12. ACS Med Chem Lett. 2011. PMID: 24900372 Free PMC article.
Discovery of novel quinoline carboxylic acid series as DGAT1 inhibitors.
Zhou G, Ting PC, Wishart G, Zorn N, Aslanian RG, Lin M, Smith M, Walker SS, Cook J, Van Heek M, Lachowicz J. Zhou G, et al. Among authors: aslanian rg. Bioorg Med Chem Lett. 2014 Apr 1;24(7):1790-4. doi: 10.1016/j.bmcl.2014.02.028. Epub 2014 Feb 19. Bioorg Med Chem Lett. 2014. PMID: 24618302
Discovery of a series of potent arylthiadiazole H(3) antagonists.
Xiao D, Palani A, Sofolarides M, Huang Y, Aslanian R, Vaccaro H, Hong L, McKittrick B, West RE Jr, Williams SM, Wu RL, Hwa J, Sondey C, Lachowicz J. Xiao D, et al. Among authors: aslanian r. Bioorg Med Chem Lett. 2011 Jan 15;21(2):861-4. doi: 10.1016/j.bmcl.2010.11.065. Epub 2010 Nov 21. Bioorg Med Chem Lett. 2011. PMID: 21186123
Discovery of fused 5,6-bicyclic heterocycles as γ-secretase modulators.
Qin J, Dhondi P, Huang X, Mandal M, Zhao Z, Pissarnitski D, Zhou W, Aslanian R, Zhu Z, Greenlee W, Clader J, Zhang L, Cohen-Williams M, Jones N, Hyde L, Palani A. Qin J, et al. Among authors: aslanian r. Bioorg Med Chem Lett. 2011 Jan 15;21(2):664-9. doi: 10.1016/j.bmcl.2010.12.012. Epub 2010 Dec 13. Bioorg Med Chem Lett. 2011. PMID: 21195610
111 results