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Year Number of Results
1975 1
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1978 1
1983 1
1990 5
1991 2
1992 1
1993 2
1994 2
1996 4
1997 4
1999 2
2000 3
2001 2
2002 2
2003 2
2004 3
2005 3
2006 4
2007 3
2008 2
2009 2
2010 3
2012 1
2013 2
2014 5
2015 2
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2019 1
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2024 2

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77 results

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Page 1
Microtubule-dependent pushing forces contribute to long-distance aster movement and centration in Xenopus laevis egg extracts.
Sulerud T, Sami AB, Li G, Kloxin A, Oakey J, Gatlin J. Sulerud T, et al. Mol Biol Cell. 2020 Dec 1;31(25):2791-2802. doi: 10.1091/mbc.E20-01-0088. Epub 2020 Oct 7. Mol Biol Cell. 2020. PMID: 33026931 Free PMC article.
Here we describe a method that combines microfluidics, hydrogels, and Xenopus laevis egg extract to investigate the mechanics of aster movement and centration. ...Importantly, the distance over which this mechanism seemed to operate was longer than that predicted by …
Here we describe a method that combines microfluidics, hydrogels, and Xenopus laevis egg extract to investigate the mechanics of a …
Aster formation in eggs of Xenopus laevis. Induction by isolated basal bodies.
Heidemann SR, Kirschner MW. Heidemann SR, et al. J Cell Biol. 1975 Oct;67(1):105-17. doi: 10.1083/jcb.67.1.105. J Cell Biol. 1975. PMID: 1236852 Free PMC article.
We have assayed various materials for their ability to induce aster formation by microinjection into unfertilized eggs of Xenopus laevis. ...Experiments in which D2O was found to stimulate aster-like fibrous areas in eggs but not oocytes suggest that the inab …
We have assayed various materials for their ability to induce aster formation by microinjection into unfertilized eggs of Xenopus …
Aster lights on RNA.
Sitterlin D. Sitterlin D. Nat Struct Mol Biol. 2005 Jun;12(6):479-80. doi: 10.1038/nsmb0605-479. Nat Struct Mol Biol. 2005. PMID: 15933733 No abstract available.
Growth, interaction, and positioning of microtubule asters in extremely large vertebrate embryo cells.
Mitchison T, Wühr M, Nguyen P, Ishihara K, Groen A, Field CM. Mitchison T, et al. Cytoskeleton (Hoboken). 2012 Oct;69(10):738-50. doi: 10.1002/cm.21050. Epub 2012 Aug 20. Cytoskeleton (Hoboken). 2012. PMID: 22786885 Free PMC article. Review.
Ray Rappaport spent many years studying microtubule asters, and how they induce cleavage furrows. Here, we review recent progress on aster structure and dynamics in zygotes and early blastomeres of Xenopus laevis and Zebrafish, where cells are extremely large …
Ray Rappaport spent many years studying microtubule asters, and how they induce cleavage furrows. Here, we review recent progress on …
Size Scaling of Microtubule Assemblies in Early Xenopus Embryos.
Mitchison TJ, Ishihara K, Nguyen P, Wühr M. Mitchison TJ, et al. Cold Spring Harb Perspect Biol. 2015 Aug 10;7(10):a019182. doi: 10.1101/cshperspect.a019182. Cold Spring Harb Perspect Biol. 2015. PMID: 26261283 Free PMC article. Review.
Zygotes and early blastomeres show a scaling mismatch between spindle and cell size. This problem is solved, we argue, by interphase asters that act to position the spindle and transport chromosomes to the center of daughter cells. These tasks are executed by the spindle i …
Zygotes and early blastomeres show a scaling mismatch between spindle and cell size. This problem is solved, we argue, by interphase aste …
Assembly of Spindles and Asters in Xenopus Egg Extracts.
Field CM, Mitchison TJ. Field CM, et al. Cold Spring Harb Protoc. 2018 Jun 1;2018(6):pdb.prot099796. doi: 10.1101/pdb.prot099796. Cold Spring Harb Protoc. 2018. PMID: 29437996 Free PMC article.
Here, we provide methods for assembly of mitotic spindles and interphase asters in Xenopus laevis egg extract, and compare them to spindles and asters in the egg and zygote. ...When interphase asters grow into each other they interact and assemble a …
Here, we provide methods for assembly of mitotic spindles and interphase asters in Xenopus laevis egg extract, and compare the …
Disassembly of Actin and Keratin Networks by Aurora B Kinase at the Midplane of Cleaving Xenopus laevis Eggs.
Field CM, Pelletier JF, Mitchison TJ. Field CM, et al. Curr Biol. 2019 Jun 17;29(12):1999-2008.e4. doi: 10.1016/j.cub.2019.05.016. Epub 2019 Jun 6. Curr Biol. 2019. PMID: 31178324 Free PMC article.
The large length scale of Xenopus laevis eggs facilitates observation of bulk cytoplasm dynamics far from the cortex during cytokinesis. ...Consistent with extract observations, we observed disassembly of the keratin network between asters in zygotes fixed before an …
The large length scale of Xenopus laevis eggs facilitates observation of bulk cytoplasm dynamics far from the cortex during cytokines …
Spindle-to-Cortex Communication in Cleaving Frog Eggs.
Mitchison TJ, Field CM. Mitchison TJ, et al. Cold Spring Harb Symp Quant Biol. 2017;82:165-171. doi: 10.1101/sqb.2017.82.033654. Epub 2017 Dec 1. Cold Spring Harb Symp Quant Biol. 2017. PMID: 29196560 Free PMC article.
At anaphase onset, huge microtubule asters grow out from the poles of the spindle and meet at the plane previously defined by the metaphase plate. ...Recruitment of CPC to aster boundaries was reconstituted in an extract system, and we observed that recruitment was …
At anaphase onset, huge microtubule asters grow out from the poles of the spindle and meet at the plane previously defined by the met …
Actin-Network Architecture Regulates Microtubule Dynamics.
Colin A, Singaravelu P, Théry M, Blanchoin L, Gueroui Z. Colin A, et al. Curr Biol. 2018 Aug 20;28(16):2647-2656.e4. doi: 10.1016/j.cub.2018.06.028. Epub 2018 Aug 9. Curr Biol. 2018. PMID: 30100343 Free article.
Yet how actin meshwork architecture affects microtubule dynamics is still unclear. Here, we reconstituted microtubule aster in the presence of a meshwork of actin filaments using confined actin-intact Xenopus egg extracts. We found that actin filament branching reduces the …
Yet how actin meshwork architecture affects microtubule dynamics is still unclear. Here, we reconstituted microtubule aster in the pr …
Branched microtubule nucleation and dynein transport organize RanGTP asters in Xenopus laevis egg extract.
Scrofani J, Ruhnow F, Chew WX, Normanno D, Nedelec F, Surrey T, Vernos I. Scrofani J, et al. Mol Biol Cell. 2024 Jan 1;35(1):ar12. doi: 10.1091/mbc.E23-10-0407. Epub 2023 Nov 22. Mol Biol Cell. 2024. PMID: 37991893 Free PMC article.
This raises the question of how branched-MT nucleation and dynein-mediated transport cooperate to organize the spindle poles. Here, we used RanGTP-dependent MT aster formation in Xenopus laevis (X. laevis) egg extract to study the interplay between these two …
This raises the question of how branched-MT nucleation and dynein-mediated transport cooperate to organize the spindle poles. Here, we used …
77 results