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Page 1
Astrocyte-endothelial interactions at the blood-brain barrier.
Abbott NJ, Rönnbäck L, Hansson E. Abbott NJ, et al. Nat Rev Neurosci. 2006 Jan;7(1):41-53. doi: 10.1038/nrn1824. Nat Rev Neurosci. 2006. PMID: 16371949 Review.
The blood-brain barrier, which is formed by the endothelial cells that line cerebral microvessels, has an important role in maintaining a precisely regulated microenvironment for reliable neuronal signalling. ...Here, we explore specific interactions b …
The blood-brain barrier, which is formed by the endothelial cells that line cerebral microvessels, has an important rol …
Astrocyte-endothelial interactions and blood-brain barrier permeability.
Abbott NJ. Abbott NJ. J Anat. 2002 Jun;200(6):629-38. doi: 10.1046/j.1469-7580.2002.00064.x. J Anat. 2002. PMID: 12162730 Free PMC article. Review.
The blood-brain barrier (BBB) is formed by brain endothelial cells lining the cerebral microvasculature, and is an important mechanism for protecting the brain from fluctuations in plasma composition, and from circulating agents such as neurotra …
The blood-brain barrier (BBB) is formed by brain endothelial cells lining the cerebral microvasculature, and is …
Imaging in vivo astrocyte/endothelial cell interactions at the blood-brain barrier.
Willis CL. Willis CL. Methods Mol Biol. 2012;814:515-29. doi: 10.1007/978-1-61779-452-0_34. Methods Mol Biol. 2012. PMID: 22144329
The goal of this chapter is to highlight methods used to demonstrate in vivo changes in astrocyte expression at the blood-brain barrier (BBB). Loss of BBB integrity is seen in many acute and chronic disease conditions. ...These studies suggest a critical role …
The goal of this chapter is to highlight methods used to demonstrate in vivo changes in astrocyte expression at the blood-brain …
A three-dimensional model of the human blood-brain barrier to analyse the transport of nanoparticles and astrocyte/endothelial interactions.
Sreekanthreddy P, Gromnicova R, Davies H, Phillips J, Romero IA, Male D. Sreekanthreddy P, et al. F1000Res. 2015 Nov 17;4:1279. doi: 10.12688/f1000research.7142.2. eCollection 2015. F1000Res. 2015. PMID: 26870320 Free PMC article.
The aim of this study was to develop a three-dimensional (3D) model of the human blood-brain barrier in vitro, which mimics the cellular architecture of the CNS and could be used to analyse the delivery of nanoparticles to cells of the CNS. ...TEM was used to …
The aim of this study was to develop a three-dimensional (3D) model of the human blood-brain barrier in vitro, which mi …
Micropatterned Neurovascular Interface to Mimic the Blood-Brain Barrier's Neurophysiology and Micromechanical Function: A BBB-on-CHIP Model.
Singh AV, Chandrasekar V, Laux P, Luch A, Dakua SP, Zamboni P, Shelar A, Yang Y, Pandit V, Tisato V, Gemmati D. Singh AV, et al. Cells. 2022 Sep 8;11(18):2801. doi: 10.3390/cells11182801. Cells. 2022. PMID: 36139383 Free PMC article.
A hybrid blood-brain barrier (BBB)-on-chip cell culture device is proposed in this study by integrating microcontact printing and perfusion co-culture to facilitate the study of BBB function under high biological fidelity. ...Biochemical regulation of BBB fun …
A hybrid blood-brain barrier (BBB)-on-chip cell culture device is proposed in this study by integrating microcontact pr …
A new dynamic in vitro model for the multidimensional study of astrocyte-endothelial cell interactions at the blood-brain barrier.
Cucullo L, McAllister MS, Kight K, Krizanac-Bengez L, Marroni M, Mayberg MR, Stanness KA, Janigro D. Cucullo L, et al. Brain Res. 2002 Oct 4;951(2):243-54. doi: 10.1016/s0006-8993(02)03167-0. Brain Res. 2002. PMID: 12270503
Blood-brain barrier endothelial cells are characterized by the presence of tight intercellular junctions, the absence of fenestrations, and a paucity of pinocytotic vesicles. ...Several systems in vitro attempt to reproduce the physical and biochemical behavi …
Blood-brain barrier endothelial cells are characterized by the presence of tight intercellular junctions, the absence o …
Cenicriviroc prevents dysregulation of astrocyte/endothelial cross talk induced by ischemia and HIV-1 via inhibiting the NLRP3 inflammasome and pyroptosis.
Fattakhov N, Ngo A, Torices S, Joseph JA, Okoro A, Moore C, Naranjo O, Becker S, Toborek M. Fattakhov N, et al. Am J Physiol Cell Physiol. 2024 Feb 1;326(2):C487-C504. doi: 10.1152/ajpcell.00600.2023. Epub 2023 Dec 25. Am J Physiol Cell Physiol. 2024. PMID: 38145295
Blood-brain barrier (BBB) breakdown is one of the pathophysiological characteristics of ischemic stroke, which may contribute to the progression of brain tissue damage and subsequent neurological impairment. ...Our results suggest that blocking NLRP3 i …
Blood-brain barrier (BBB) breakdown is one of the pathophysiological characteristics of ischemic stroke, which may cont …
Use of an in vitro system to study the effects of lead on astrocyte-endothelial cell interactions: a model for studying toxic injury to the blood-brain barrier.
Gebhart AM, Goldstein GW. Gebhart AM, et al. Toxicol Appl Pharmacol. 1988 Jun 30;94(2):191-206. doi: 10.1016/0041-008x(88)90261-x. Toxicol Appl Pharmacol. 1988. PMID: 2898824 Free article.
We investigated the effect of inorganic lead on the interaction of immature rat astrocytes and bovine adrenal endothelial cells. The two cell types were cultured alone and in coculture in the presence or absence of lead acetate for up to 1 week. A battery of cell specific …
We investigated the effect of inorganic lead on the interaction of immature rat astrocytes and bovine adrenal endothelial cells. The …
Molecular Mechanisms of Proteins - Targets for SARS-CoV-2 (Review).
Morgun AV, Salmin VV, Boytsova EB, Lopatina OL, Salmina AB. Morgun AV, et al. Sovrem Tekhnologii Med. 2021;12(6):98-108. doi: 10.17691/stm2020.12.6.11. Epub 2020 Dec 28. Sovrem Tekhnologii Med. 2021. PMID: 34796023 Free PMC article. Review.
By day 4, an excessive production of proinflammatory cytokines in the brain, local neuroinflammation, breakdown of the blood-brain barrier, and impaired neuroplasticity are detected. ...This molecule is expressed on the endothelial cells of cerebral mi …
By day 4, an excessive production of proinflammatory cytokines in the brain, local neuroinflammation, breakdown of the blood- …
Astrocyte-derived fatty acid-binding protein 7 protects blood-brain barrier integrity through a caveolin-1/MMP signaling pathway following traumatic brain injury.
Rui Q, Ni H, Lin X, Zhu X, Li D, Liu H, Chen G. Rui Q, et al. Exp Neurol. 2019 Dec;322:113044. doi: 10.1016/j.expneurol.2019.113044. Epub 2019 Aug 24. Exp Neurol. 2019. PMID: 31454490
The astrocyte-endothelial cell interaction is crucial for normal brain homeostasis and blood-brain barrier (BBB) disruption in pathological conditions. ...Administration of recombinant FABP7 significantly ameliorated TBI-induced ne …
The astrocyte-endothelial cell interaction is crucial for normal brain homeostasis and blood-brain …
25 results