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A validated LC-MS/MS method for the simultaneous determination of BMS-791325, a hepatitis C virus NS5B RNA polymerase inhibitor, and its metabolite in plasma.
Yuan L, Jiang H, Zheng N, Xia YQ, Ouyang Z, Zeng J, Akinsanya B, Valentine JL, Moehlenkamp JD, Deng Y, Aubry AF, Arnold ME. Yuan L, et al. Among authors: aubry af. J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Dec 15;973C:1-8. doi: 10.1016/j.jchromb.2014.10.005. Epub 2014 Oct 12. J Chromatogr B Analyt Technol Biomed Life Sci. 2014. PMID: 25464088
Sensitive and accurate liquid chromatography-tandem mass spectrometry methods for quantitative determination of a novel hepatitis C NS5B inhibitor BMS-791325 and its active metabolite in human plasma and urine.
Jiang H, Demers R, Kandoussi H, Burrell R, Eley T, Kadiyala P, Cojocaru L, Baker C, Ryan J, Aubry AF, Arnold ME, Zeng J. Jiang H, et al. Among authors: aubry af. J Pharm Biomed Anal. 2015 Mar 25;107:17-23. doi: 10.1016/j.jpba.2014.12.011. Epub 2014 Dec 17. J Pharm Biomed Anal. 2015. PMID: 25562845
Multiplexed LC-MS/MS method for the simultaneous quantitation of three novel hepatitis C antivirals, daclatasvir, asunaprevir, and beclabuvir in human plasma.
Jiang H, Kandoussi H, Zeng J, Wang J, Demers R, Eley T, He B, Burrell R, Easter J, Kadiyala P, Pursley J, Cojocaru L, Baker C, Ryan J, Aubry AF, Arnold ME. Jiang H, et al. Among authors: aubry af. J Pharm Biomed Anal. 2015 Mar 25;107:409-18. doi: 10.1016/j.jpba.2015.01.027. Epub 2015 Jan 20. J Pharm Biomed Anal. 2015. PMID: 25676854
Challenges and solutions in the bioanalysis of BMS-986094 and its metabolites including a highly polar, active nucleoside triphosphate in plasma and tissues using LC-MS/MS.
Liu A, Lute J, Gu H, Wang B, Trouba KJ, Arnold ME, Aubry AF, Wang J. Liu A, et al. Among authors: aubry af. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Sep 1;1000:29-40. doi: 10.1016/j.jchromb.2015.07.006. Epub 2015 Jul 13. J Chromatogr B Analyt Technol Biomed Life Sci. 2015. PMID: 26209768
75 results