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Epstein-Barr virus-encoded EBNA2 alters immune checkpoint PD-L1 expression by downregulating miR-34a in B-cell lymphomas.
Anastasiadou E, Stroopinsky D, Alimperti S, Jiao AL, Pyzer AR, Cippitelli C, Pepe G, Severa M, Rosenblatt J, Etna MP, Rieger S, Kempkes B, Coccia EM, Sui SJH, Chen CS, Uccini S, Avigan D, Faggioni A, Trivedi P, Slack FJ. Anastasiadou E, et al. Among authors: avigan d. Leukemia. 2019 Jan;33(1):132-147. doi: 10.1038/s41375-018-0178-x. Epub 2018 Jun 26. Leukemia. 2019. PMID: 29946193 Free PMC article.
Dendritic cell fusion vaccines for cancer immunotherapy.
Rosenblatt J, Kufe D, Avigan D. Rosenblatt J, et al. Among authors: avigan d. Expert Opin Biol Ther. 2005 May;5(5):703-15. doi: 10.1517/14712598.5.5.703. Expert Opin Biol Ther. 2005. PMID: 15934845 Review.
PML targeting eradicates quiescent leukaemia-initiating cells.
Ito K, Bernardi R, Morotti A, Matsuoka S, Saglio G, Ikeda Y, Rosenblatt J, Avigan DE, Teruya-Feldstein J, Pandolfi PP. Ito K, et al. Nature. 2008 Jun 19;453(7198):1072-8. doi: 10.1038/nature07016. Epub 2008 May 11. Nature. 2008. PMID: 18469801 Free PMC article.
Fusions of dendritic cells with breast carcinoma stimulate the expansion of regulatory T cells while concomitant exposure to IL-12, CpG oligodeoxynucleotides, and anti-CD3/CD28 promotes the expansion of activated tumor reactive cells.
Vasir B, Wu Z, Crawford K, Rosenblatt J, Zarwan C, Bissonnette A, Kufe D, Avigan D. Vasir B, et al. Among authors: avigan d. J Immunol. 2008 Jul 1;181(1):808-21. doi: 10.4049/jimmunol.181.1.808. J Immunol. 2008. PMID: 18566447 Free PMC article.
Cellular immunotherapy for multiple myeloma.
Rosenblatt J, Avigan D. Rosenblatt J, et al. Among authors: avigan d. Best Pract Res Clin Haematol. 2008 Sep;21(3):559-77. doi: 10.1016/j.beha.2008.07.007. Best Pract Res Clin Haematol. 2008. PMID: 18790455 Review.
Generation of tumor-specific T lymphocytes using dendritic cell/tumor fusions and anti-CD3/CD28.
Rosenblatt J, Wu Z, Vasir B, Zarwan C, Stone R, Mills H, Friedman T, Konstantinopoulos PA, Spentzos D, Ghebremichael M, Stevenson K, Neuberg D, Levine JD, Joyce R, Tzachanis D, Boussiotis V, Kufe D, Avigan D. Rosenblatt J, et al. Among authors: avigan d. J Immunother. 2010 Feb-Mar;33(2):155-66. doi: 10.1097/CJI.0b013e3181bed253. J Immunother. 2010. PMID: 20145548 Free PMC article.
Vaccination with dendritic cell/tumor fusion cells results in cellular and humoral antitumor immune responses in patients with multiple myeloma.
Rosenblatt J, Vasir B, Uhl L, Blotta S, Macnamara C, Somaiya P, Wu Z, Joyce R, Levine JD, Dombagoda D, Yuan YE, Francoeur K, Fitzgerald D, Richardson P, Weller E, Anderson K, Kufe D, Munshi N, Avigan D. Rosenblatt J, et al. Among authors: avigan d. Blood. 2011 Jan 13;117(2):393-402. doi: 10.1182/blood-2010-04-277137. Epub 2010 Oct 28. Blood. 2011. PMID: 21030562 Free PMC article. Clinical Trial.
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