Ayers GD - Search Results

1

Myeloid IKKβ promotes antitumor immunity by modulating CCL11 and the innate immune response.

Yang J, Hawkins OE, Barham W, Gilchuk P, Boothby M, Ayers GD, Joyce S, Karin M, Yull FE, Richmond A. Yang J, et al. Among authors: ayers gd. Cancer Res. 2014 Dec 15;74(24):7274-84. doi: 10.1158/0008-5472.CAN-14-1091. Epub 2014 Oct 21. Cancer Res. 2014. PMID: 25336190 Free PMC article.

2

INK4a/ARF [corrected] inactivation with activation of the NF-κB/IL-6 pathway is sufficient to drive the development and growth of angiosarcoma.

Yang J, Kantrow S, Sai J, Hawkins OE, Boothby M, Ayers GD, Young ED, Demicco EG, Lazar AJ, Lev D, Richmond A. Yang J, et al. Among authors: ayers gd. Cancer Res. 2012 Sep 15;72(18):4682-95. doi: 10.1158/0008-5472.CAN-12-0440. Epub 2012 Jul 26. Cancer Res. 2012. PMID: 22836752 Free PMC article.

3

Mdm2 and aurora kinase a inhibitors synergize to block melanoma growth by driving apoptosis and immune clearance of tumor cells.

Vilgelm AE, Pawlikowski JS, Liu Y, Hawkins OE, Davis TA, Smith J, Weller KP, Horton LW, McClain CM, Ayers GD, Turner DC, Essaka DC, Stewart CF, Sosman JA, Kelley MC, Ecsedy JA, Johnston JN, Richmond A. Vilgelm AE, et al. Among authors: ayers gd. Cancer Res. 2015 Jan 1;75(1):181-93. doi: 10.1158/0008-5472.CAN-14-2405. Epub 2014 Nov 14. Cancer Res. 2015. PMID: 25398437 Free PMC article.

4

PI3K Inhibition Reduces Mammary Tumor Growth and Facilitates Antitumor Immunity and Anti-PD1 Responses.

Sai J, Owens P, Novitskiy SV, Hawkins OE, Vilgelm AE, Yang J, Sobolik T, Lavender N, Johnson AC, McClain C, Ayers GD, Kelley MC, Sanders M, Mayer IA, Moses HL, Boothby M, Richmond A. Sai J, et al. Among authors: ayers gd. Clin Cancer Res. 2017 Jul 1;23(13):3371-3384. doi: 10.1158/1078-0432.CCR-16-2142. Epub 2016 Dec 21. Clin Cancer Res. 2017. PMID: 28003307 Free PMC article.

5

Loss of CXCR4 in Myeloid Cells Enhances Antitumor Immunity and Reduces Melanoma Growth through NK Cell and FASL Mechanisms.

Yang J, Kumar A, Vilgelm AE, Chen SC, Ayers GD, Novitskiy SV, Joyce S, Richmond A. Yang J, et al. Among authors: ayers gd. Cancer Immunol Res. 2018 Oct;6(10):1186-1198. doi: 10.1158/2326-6066.CIR-18-0045. Epub 2018 Aug 14. Cancer Immunol Res. 2018. PMID: 30108045 Free PMC article.

6

Targeted Deletion of CXCR2 in Myeloid Cells Alters the Tumor Immune Environment to Improve Antitumor Immunity.

Yang J, Yan C, Vilgelm AE, Chen SC, Ayers GD, Johnson CA, Richmond A. Yang J, et al. Among authors: ayers gd. Cancer Immunol Res. 2021 Feb;9(2):200-213. doi: 10.1158/2326-6066.CIR-20-0312. Epub 2020 Nov 11. Cancer Immunol Res. 2021. PMID: 33177110 Free PMC article.

7

Conditional ablation of Ikkb inhibits melanoma tumor development in mice.

Yang J, Splittgerber R, Yull FE, Kantrow S, Ayers GD, Karin M, Richmond A. Yang J, et al. Among authors: ayers gd. J Clin Invest. 2010 Jul;120(7):2563-74. doi: 10.1172/JCI42358. Epub 2010 Jun 7. J Clin Invest. 2010. PMID: 20530876 Free PMC article.

8

Connecting the Dots: Therapy-Induced Senescence and a Tumor-Suppressive Immune Microenvironment.

Vilgelm AE, Johnson CA, Prasad N, Yang J, Chen SC, Ayers GD, Pawlikowski JS, Raman D, Sosman JA, Kelley M, Ecsedy JA, Shyr Y, Levy SE, Richmond A. Vilgelm AE, et al. Among authors: ayers gd. J Natl Cancer Inst. 2015 Dec 30;108(6):djv406. doi: 10.1093/jnci/djv406. Print 2016 Jun. J Natl Cancer Inst. 2015. PMID: 26719346 Free PMC article.

9

The Yin/Yan of CCL2: a minor role in neutrophil anti-tumor activity in vitro but a major role on the outgrowth of metastatic breast cancer lesions in the lung in vivo.

Lavender N, Yang J, Chen SC, Sai J, Johnson CA, Owens P, Ayers GD, Richmond A. Lavender N, et al. Among authors: ayers gd. BMC Cancer. 2017 Jan 31;17(1):88. doi: 10.1186/s12885-017-3074-2. BMC Cancer. 2017. PMID: 28143493 Free PMC article.

10

Metastatic Melanoma Patient-Derived Xenografts Respond to MDM2 Inhibition as a Single Agent or in Combination with BRAF/MEK Inhibition.

Shattuck-Brandt RL, Chen SC, Murray E, Johnson CA, Crandall H, O'Neal JF, Al-Rohil RN, Nebhan CA, Bharti V, Dahlman KB, Ayers GD, Yan C, Kelley MC, Kauffmann RM, Hooks M, Grau A, Johnson DB, Vilgelm AE, Richmond A. Shattuck-Brandt RL, et al. Among authors: ayers gd. Clin Cancer Res. 2020 Jul 15;26(14):3803-3818. doi: 10.1158/1078-0432.CCR-19-1895. Epub 2020 Mar 31. Clin Cancer Res. 2020. PMID: 32234759 Free PMC article.

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