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Targeted inhibition of gut bacterial β-glucuronidase activity enhances anticancer drug efficacy.
Bhatt AP, Pellock SJ, Biernat KA, Walton WG, Wallace BD, Creekmore BC, Letertre MM, Swann JR, Wilson ID, Roques JR, Darr DB, Bailey ST, Montgomery SA, Roach JM, Azcarate-Peril MA, Sartor RB, Gharaibeh RZ, Bultman SJ, Redinbo MR. Bhatt AP, et al. Proc Natl Acad Sci U S A. 2020 Mar 31;117(13):7374-7381. doi: 10.1073/pnas.1918095117. Epub 2020 Mar 13. Proc Natl Acad Sci U S A. 2020. PMID: 32170007 Free PMC article.
Emerging Technologies for Gut Microbiome Research.
Arnold JW, Roach J, Azcarate-Peril MA. Arnold JW, et al. Trends Microbiol. 2016 Nov;24(11):887-901. doi: 10.1016/j.tim.2016.06.008. Epub 2016 Jul 15. Trends Microbiol. 2016. PMID: 27426971 Free PMC article. Review.
A double-blind, 377-subject randomized study identifies Ruminococcus, Coprococcus, Christensenella, and Collinsella as long-term potential key players in the modulation of the gut microbiome of lactose intolerant individuals by galacto-oligosaccharides.
Azcarate-Peril MA, Roach J, Marsh A, Chey WD, Sandborn WJ, Ritter AJ, Savaiano DA, Klaenhammer TR. Azcarate-Peril MA, et al. Gut Microbes. 2021 Jan-Dec;13(1):1957536. doi: 10.1080/19490976.2021.1957536. Gut Microbes. 2021. PMID: 34365905 Free PMC article. Clinical Trial.
Association of Increased Serum Lipopolysaccharide, But Not Microbial Dysbiosis, With Obesity-Related Osteoarthritis.
Loeser RF, Arbeeva L, Kelley K, Fodor AA, Sun S, Ulici V, Longobardi L, Cui Y, Stewart DA, Sumner SJ, Azcarate-Peril MA, Sartor RB, Carroll IM, Renner JB, Jordan JM, Nelson AE. Loeser RF, et al. Arthritis Rheumatol. 2022 Feb;74(2):227-236. doi: 10.1002/art.41955. Epub 2022 Jan 4. Arthritis Rheumatol. 2022. PMID: 34423918 Free PMC article.
A germ-free humanized mouse model shows the contribution of resident microbiota to human-specific pathogen infection.
Wahl A, Yao W, Liao B, Chateau M, Richardson C, Ling L, Franks A, Senthil K, Doyon G, Li F, Frost J, Whitehurst CB, Pagano JS, Fletcher CA, Azcarate-Peril MA, Hudgens MG, Rogala AR, Tucker JD, McGowan I, Sartor RB, Garcia JV. Wahl A, et al. Among authors: azcarate peril ma. Nat Biotechnol. 2023 Aug 10:10.1038/s41587-023-01906-5. doi: 10.1038/s41587-023-01906-5. Online ahead of print. Nat Biotechnol. 2023. PMID: 37563299
111 results