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Target Score-A Proteomics Data Selection Tool Applied to Esophageal Cancer Identifies GLUT1-Sialyl Tn Glycoforms as Biomarkers of Cancer Aggressiveness.
Cotton S, Ferreira D, Soares J, Peixoto A, Relvas-Santos M, Azevedo R, Piairo P, Diéguez L, Palmeira C, Lima L, Silva AMN, Lara Santos L, Ferreira JA. Cotton S, et al. Among authors: azevedo r. Int J Mol Sci. 2021 Feb 7;22(4):1664. doi: 10.3390/ijms22041664. Int J Mol Sci. 2021. PMID: 33562270 Free PMC article.
Hypoxia enhances the malignant nature of bladder cancer cells and concomitantly antagonizes protein O-glycosylation extension.
Peixoto A, Fernandes E, Gaiteiro C, Lima L, Azevedo R, Soares J, Cotton S, Parreira B, Neves M, Amaro T, Tavares A, Teixeira F, Palmeira C, Rangel M, Silva AM, Reis CA, Santos LL, Oliveira MJ, Ferreira JA. Peixoto A, et al. Among authors: azevedo r. Oncotarget. 2016 Sep 27;7(39):63138-63157. doi: 10.18632/oncotarget.11257. Oncotarget. 2016. PMID: 27542232 Free PMC article.
Targeted O-glycoproteomics explored increased sialylation and identified MUC16 as a poor prognosis biomarker in advanced-stage bladder tumours.
Cotton S, Azevedo R, Gaiteiro C, Ferreira D, Lima L, Peixoto A, Fernandes E, Neves M, Neves D, Amaro T, Cruz R, Tavares A, Rangel M, Silva AMN, Santos LL, Ferreira JA. Cotton S, et al. Among authors: azevedo r. Mol Oncol. 2017 Aug;11(8):895-912. doi: 10.1002/1878-0261.12035. Epub 2017 Mar 2. Mol Oncol. 2017. PMID: 28156048 Free PMC article.
Sialyl-Tn identifies muscle-invasive bladder cancer basal and luminal subtypes facing decreased survival, being expressed by circulating tumor cells and metastases.
Lima L, Neves M, Oliveira MI, Dieguez L, Freitas R, Azevedo R, Gaiteiro C, Soares J, Ferreira D, Peixoto A, Fernandes E, Montezuma D, Tavares A, Ribeiro R, Castro A, Oliveira M, Fraga A, Reis CA, Santos LL, Ferreira JA. Lima L, et al. Among authors: azevedo r. Urol Oncol. 2017 Dec;35(12):675.e1-675.e8. doi: 10.1016/j.urolonc.2017.08.012. Epub 2017 Sep 12. Urol Oncol. 2017. PMID: 28911924
1,113 results