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Protein-coding variants contribute to the risk of atopic dermatitis and skin-specific gene expression.
Mucha S, Baurecht H, Novak N, Rodríguez E, Bej S, Mayr G, Emmert H, Stölzl D, Gerdes S, Jung ES, Degenhardt F, Hübenthal M, Ellinghaus E, Kässens JC, Wienbrandt L, Lieb W, Müller-Nurasyid M, Hotze M, Dand N, Grosche S, Marenholz I, Arnold A, Homuth G, Schmidt CO, Wehkamp U, Nöthen MM, Hoffmann P, Paternoster L, Standl M; Early Genetics and Lifecourse Epidemiology (EAGLE) Eczema Consortium; Bønnelykke K, Ahluwalia TS, Bisgaard H, Peters A, Gieger C, Waldenberger M, Schulz H, Strauch K, Werfel T, Lee YA, Wolfien M, Rosenstiel P, Wolkenhauer O, Schreiber S, Franke A, Weidinger S, Ellinghaus D. Mucha S, et al. Among authors: bonnelykke k. J Allergy Clin Immunol. 2020 Apr;145(4):1208-1218. doi: 10.1016/j.jaci.2019.10.030. Epub 2019 Nov 9. J Allergy Clin Immunol. 2020. PMID: 31707051
Age dependent systemic exposure to inhaled salbutamol.
Bønnelykke K, Jespersen JJ, Bisgaard H. Bønnelykke K, et al. Br J Clin Pharmacol. 2007 Aug;64(2):241-4. doi: 10.1111/j.1365-2125.2007.02868.x. Epub 2007 Mar 1. Br J Clin Pharmacol. 2007. PMID: 17335545 Free PMC article. Clinical Trial.
Extrapolating evidence beyond age groups.
Bisgaard H, Bønnelykke K. Bisgaard H, et al. Among authors: bonnelykke k. J Allergy Clin Immunol. 2008 Apr;121(4):1066-7; author reply 1067-8. doi: 10.1016/j.jaci.2008.01.068. Epub 2008 Mar 5. J Allergy Clin Immunol. 2008. PMID: 18325574 No abstract available.
Sensitization does not develop in utero.
Bønnelykke K, Pipper CB, Bisgaard H. Bønnelykke K, et al. J Allergy Clin Immunol. 2008 Mar;121(3):646-51. doi: 10.1016/j.jaci.2007.12.1149. J Allergy Clin Immunol. 2008. PMID: 18328892
Chromosome 17q21 gene variants are associated with asthma and exacerbations but not atopy in early childhood.
Bisgaard H, Bønnelykke K, Sleiman PM, Brasholt M, Chawes B, Kreiner-Møller E, Stage M, Kim C, Tavendale R, Baty F, Pipper CB, Palmer CN, Hakonarsson H. Bisgaard H, et al. Among authors: bonnelykke k. Am J Respir Crit Care Med. 2009 Feb 1;179(3):179-85. doi: 10.1164/rccm.200809-1436OC. Epub 2008 Nov 21. Am J Respir Crit Care Med. 2009. PMID: 19029000
17q12-21 variants interact with smoke exposure as a risk factor for pediatric asthma but are equally associated with early-onset versus late-onset asthma in North Americans of European ancestry.
Flory JH, Sleiman PM, Christie JD, Annaiah K, Bradfield J, Kim CE, Glessner J, Imielinski M, Li H, Frackelton EC, Cuiping H, Otieno G, Thomas K, Smith R, Glaberson W, Garris M, Chiavacci R, Allen J, Spergel J, Grundmeier R, Grunstein M, Magnusson M, Grant SF, Bønnelykke K, Bisgaard H, Hakonarson H. Flory JH, et al. Among authors: bonnelykke k. J Allergy Clin Immunol. 2009 Sep;124(3):605-7. doi: 10.1016/j.jaci.2009.05.047. Epub 2009 Aug 5. J Allergy Clin Immunol. 2009. PMID: 19660801 No abstract available.
Variants of DENND1B associated with asthma in children.
Sleiman PM, Flory J, Imielinski M, Bradfield JP, Annaiah K, Willis-Owen SA, Wang K, Rafaels NM, Michel S, Bonnelykke K, Zhang H, Kim CE, Frackelton EC, Glessner JT, Hou C, Otieno FG, Santa E, Thomas K, Smith RM, Glaberson WR, Garris M, Chiavacci RM, Beaty TH, Ruczinski I, Orange JS, Allen J, Spergel JM, Grundmeier R, Mathias RA, Christie JD, von Mutius E, Cookson WO, Kabesch M, Moffatt MF, Grunstein MM, Barnes KC, Devoto M, Magnusson M, Li H, Grant SF, Bisgaard H, Hakonarson H. Sleiman PM, et al. Among authors: bonnelykke k. N Engl J Med. 2010 Jan 7;362(1):36-44. doi: 10.1056/NEJMoa0901867. Epub 2009 Dec 23. N Engl J Med. 2010. PMID: 20032318 Free article.
291 results