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Botanicals as Modulators of Neuroplasticity: Focus on BDNF.
Sangiovanni E, Brivio P, Dell'Agli M, Calabrese F. Sangiovanni E, et al. Neural Plast. 2017;2017:5965371. doi: 10.1155/2017/5965371. Epub 2017 Dec 31. Neural Plast. 2017. PMID: 29464125 Free PMC article. Review.
The involvement of brain-derived neurotrophic factor (BDNF) in different central nervous system (CNS) diseases suggests that this neurotrophin may represent an interesting and reliable therapeutic target. ...Pennell, Coffea arabica L., Crocus sa …
The involvement of brain-derived neurotrophic factor (BDNF) in different central nervous system (CNS) dis …
Lead acetate induces hippocampal pyramidal neuron degeneration in mice via up-regulation of executioner caspase-3, oxido-inflammatory stress expression and decreased BDNF and cholinergic activity: Reversal effects of Gingko biloba supplement.
Ben-Azu B, Adebayo OG, Wopara I, Aduema W, Onyeleonu I, Umoren EB, Kolawole TA, Ebo OT, Akpotu AE, Ajibo DN, Onuoha OG. Ben-Azu B, et al. J Trace Elem Med Biol. 2022 May;71:126919. doi: 10.1016/j.jtemb.2021.126919. Epub 2021 Dec 24. J Trace Elem Med Biol. 2022. PMID: 35038618
PURPOSE: It has been hypothesized that compounds with strong anti-oxidant activity might mitigate lead-induced neurotoxicity that resulted to neuronal degeneration.Ginkgo biloba supplement (GB-S) is a neuroactive supplement which has been reported to demonstrate neu …
PURPOSE: It has been hypothesized that compounds with strong anti-oxidant activity might mitigate lead-induced neurotoxicity that resulted t …
BDNF as a Putative Target for Standardized Extract of Ginkgo biloba-Induced Persistence of Object Recognition Memory.
Muratori BG, Zamberlam CR, Mendes TB, Nozima BHN, Cerutti JM, Cerutti SM. Muratori BG, et al. Molecules. 2021 Jun 1;26(11):3326. doi: 10.3390/molecules26113326. Molecules. 2021. PMID: 34206011 Free PMC article.
Despite considerable progress on the study of the effect of standardized extract of Gingko biloba (EGb) on memory processes, our understanding of its role in the persistence of long-term memory (LTM) and the molecular mechanism underlying its effect, particularly ep …
Despite considerable progress on the study of the effect of standardized extract of Gingko biloba (EGb) on memory processes, o …
Polyherbal and Multimodal Treatments: Kaempferol- and Quercetin-Rich Herbs Alleviate Symptoms of Alzheimer's Disease.
Alexander C, Parsaee A, Vasefi M. Alexander C, et al. Biology (Basel). 2023 Nov 20;12(11):1453. doi: 10.3390/biology12111453. Biology (Basel). 2023. PMID: 37998052 Free PMC article. Review.
We followed PRISMA guidelines to identify potential herbal treatments, their associated medicinal phytochemicals, and the potential mechanisms of these treatments. Common herbs, including Ginkgo biloba, Camellia sinensis, Glycyrrhiza uralensis, Cyperus rotundus, and …
We followed PRISMA guidelines to identify potential herbal treatments, their associated medicinal phytochemicals, and the potential mechanis …
Anti-depressant natural flavonols modulate BDNF and beta amyloid in neurons and hippocampus of double TgAD mice.
Hou Y, Aboukhatwa MA, Lei DL, Manaye K, Khan I, Luo Y. Hou Y, et al. Neuropharmacology. 2010 May;58(6):911-20. doi: 10.1016/j.neuropharm.2009.11.002. Epub 2009 Nov 14. Neuropharmacology. 2010. PMID: 19917299 Free PMC article.
John's wort warrant investigating new anti-depressant drugs. Anti-depressant effects of ginkgo biloba extract (EGb 761) have been demonstrated in animal models of depression and in human volunteers. We report here that ginkgo flavonols quercetin and kaempfero …
John's wort warrant investigating new anti-depressant drugs. Anti-depressant effects of ginkgo biloba extract (EGb 761) have b …
[Ginkgolide B: mechanisms of neurobiological effects, prospects for use in the therapy of Alzheimer's disease].
Berezutsky MA, Durnova NA, Andronova TA. Berezutsky MA, et al. Zh Nevrol Psikhiatr Im S S Korsakova. 2024;124(4):22-27. doi: 10.17116/jnevro202412404122. Zh Nevrol Psikhiatr Im S S Korsakova. 2024. PMID: 38676673 Review. Russian.
Ginkgolide B is a diterpene trilactone isolated from the leaves of the relict woody plant Ginkgo biloba L., which has been used for thousands of years in traditional Chinese medicine as a neuroprotective agent. ...In vivo experiments have shown that this substance s …
Ginkgolide B is a diterpene trilactone isolated from the leaves of the relict woody plant Ginkgo biloba L., which has been use …
Brain-derived neurotrophic factor levels and its Val66Met gene polymorphism predict tardive dyskinesia treatment response to Ginkgo biloba.
Zhang XY, Zhang WF, Zhou DF, Chen DC, Xiu MH, Wu HR, Haile CN, Kosten TA, Kosten TR. Zhang XY, et al. Biol Psychiatry. 2012 Oct 15;72(8):700-6. doi: 10.1016/j.biopsych.2012.04.032. Epub 2012 Jun 12. Biol Psychiatry. 2012. PMID: 22695185 Clinical Trial.
BACKGROUND: Tardive dyskinesia (TD) has no well-accepted treatments or known pathophysiology, but low brain-derived neurotrophic factor (BDNF) may play an important role in its pathophysiology. Ginkgo biloba (EGb-761) is a potent a …
BACKGROUND: Tardive dyskinesia (TD) has no well-accepted treatments or known pathophysiology, but low brain-derived neurotr
[Cellular and molecular effects of the antidepressant hyperforin on brain cells: Review of the literature].
Bouron A, Lorrain E. Bouron A, et al. Encephale. 2014 Apr;40(2):108-13. doi: 10.1016/j.encep.2013.03.004. Epub 2013 Jun 29. Encephale. 2014. PMID: 23816060 Review. French.
INTRODUCTION: Hypericum perforatum is, with Ginkgo biloba, one of the most frequently prescribed medicinal plants in the world. ...This leads to an up-regulation of the expression of the brain-derived neurotrophic factor (BDNF) rec …
INTRODUCTION: Hypericum perforatum is, with Ginkgo biloba, one of the most frequently prescribed medicinal plants in the world …
Cytisine-N-methylene-(5,7,4(')-trihydroxy)- isoflavone ameliorates ischemic stroke-induced brain injury in mouse by regulating the oxidative stress and BDNF-Trkb/Akt pathway.
Li Y, Fan F, Liu Q. Li Y, et al. Eur J Pharmacol. 2024 Mar 15;974:176512. doi: 10.1016/j.ejphar.2024.176512. Online ahead of print. Eur J Pharmacol. 2024. PMID: 38493912
RESULTS: Our results show that intragastric administration of LY01 improves ischemic stroke behaviors in mice, as demonstrated by neurological score, infarct volume, cerebral water content, rotarod test for activity. Compared with the model group, the ginkgo biloba
RESULTS: Our results show that intragastric administration of LY01 improves ischemic stroke behaviors in mice, as demonstrated by neurologic …
A Mixture of Ginkgo biloba L. Leaf and Hericium erinaceus (Bull.) Pers. Fruit Extract Attenuates Scopolamine-Induced Memory Impairments in Mice.
Hong SM, Yoon DH, Lee MK, Lee JK, Kim SY. Hong SM, et al. Oxid Med Cell Longev. 2022 Jan 27;2022:9973678. doi: 10.1155/2022/9973678. eCollection 2022. Oxid Med Cell Longev. 2022. PMID: 35126824 Free PMC article.
In cholinergic dysfunction, it is well known that impaired cAMP response element-binding protein (CREB) and brain-derived neurotrophic factor (BDNF) signaling are major pathological markers and are some of the strategies for the development of A …
In cholinergic dysfunction, it is well known that impaired cAMP response element-binding protein (CREB) and brain-derived n
30 results