Yindan Xinnaotong Soft Capsule improves post-ischemic stroke recovery by regulating CREB/BDNF-mediated synaptic plasticity and CREB/VEGFA-mediated angiogenesis.
Cheng C, Liu H, Guan G, Fei Q, Zhao M, Wang H, Wang R, Hu L, Li X, Wu H, Fan G, Jiang M, Zhu Y, Lyu M.
Cheng C, et al.
Phytomedicine. 2025 Oct;146:157155. doi: 10.1016/j.phymed.2025.157155. Epub 2025 Aug 11.
Phytomedicine. 2025.
PMID: 40819643
A total of 535 differentially expressed genes analysis revealed that CREB signaling with the key targets of CREB, BDNF, and VEGFA was the central mechanism. The synaptic plasticity marker of synaptophysin and angiogenesis marker of CD31 were upregulated in brain tissues an …
A total of 535 differentially expressed genes analysis revealed that CREB signaling with the key targets of CREB, BDNF, and VEGFA was …