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BH3-only proteins in rheumatoid arthritis: potential targets for therapeutic intervention.
Hutcheson J, Perlman H. Hutcheson J, et al. Oncogene. 2008 Dec;27 Suppl 1(Suppl 1):S168-75. doi: 10.1038/onc.2009.54. Oncogene. 2008. PMID: 19641502 Free PMC article. Review.
Rheumatoid arthritis (RA) is a debilitating disease, resulting in the destruction of bone and cartilage, and in the permanent disfigurement of joints. ...We also suggest a role for BH3-mimetic drugs as potential therapeutics in the treatment of RA....
Rheumatoid arthritis (RA) is a debilitating disease, resulting in the destruction of bone and cartilage, and in the permanent …
Noxa in rheumatic diseases: present understanding and future impact.
Cottier KE, Fogle EM, Fox DA, Ahmed S. Cottier KE, et al. Rheumatology (Oxford). 2014 Sep;53(9):1539-46. doi: 10.1093/rheumatology/ket408. Epub 2013 Dec 17. Rheumatology (Oxford). 2014. PMID: 24352336 Free PMC article. Review.
Impaired programmed cell death is an important contributing mechanism in the development of chronic inflammatory and autoimmune diseases. Overexpression of Bcl-2 family proteins in such diseases has led to the concept of targeted suppression of these proteins …
Impaired programmed cell death is an important contributing mechanism in the development of chronic inflammatory and autoimmune diseases. Ov …