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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1993 3
1994 4
1995 35
1996 90
1997 147
1998 213
1999 248
2000 250
2001 286
2002 345
2003 311
2004 363
2005 367
2006 424
2007 432
2008 456
2009 503
2010 541
2011 591
2012 575
2013 573
2014 649
2015 727
2016 782
2017 821
2018 838
2019 930
2020 1051
2021 1065
2022 958
2023 1048
2024 457

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14,321 results

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Page 1
BRCA2 gene mutation in cancer.
Xie C, Luo J, He Y, Jiang L, Zhong L, Shi Y. Xie C, et al. Medicine (Baltimore). 2022 Nov 11;101(45):e31705. doi: 10.1097/MD.0000000000031705. Medicine (Baltimore). 2022. PMID: 36397405 Free PMC article. Review.
Breast cancer susceptibility gene 2 (BRCA2) is the main gene associated with hereditary breast cancers. However, a mutation in BRCA2 has also been found in other tumors, such as ovarian, pancreatic, thyroid, gastric, laryngeal, and prostate cancers …
Breast cancer susceptibility gene 2 (BRCA2) is the main gene associated with hereditary breast cancers. However, a muta …
Breast cancer genes: beyond BRCA1 and BRCA2.
Filippini SE, Vega A. Filippini SE, et al. Front Biosci (Landmark Ed). 2013 Jun 1;18(4):1358-72. doi: 10.2741/4185. Front Biosci (Landmark Ed). 2013. PMID: 23747889 Free article. Review.
Familial breast cancer (about 30 percent of patients), often seen in families with a high incidence of BC, has been associated with a number of high-, moderate-, and low-penetrance susceptibility genes. Family linkage studies have identified high-penetrance genes …
Familial breast cancer (about 30 percent of patients), often seen in families with a high incidence of BC, has been associated with a …
BRCA1 and BRCA2 mutations and breast cancer.
Narod SA, Salmena L. Narod SA, et al. Discov Med. 2011 Nov;12(66):445-53. Discov Med. 2011. PMID: 22127115 Free article.
The goals of treatment for a woman with a BRCA-associated breast cancer should be to prevent recurrence of the initial cancer and to prevent second primary breast and ovarian cancers. Women with breast cancer and a BRCA1 mutation may benefit from tailo …
The goals of treatment for a woman with a BRCA-associated breast cancer should be to prevent recurrence of the initial cancer …
The BRCA1 and BRCA2 Genes in Early-Onset Breast Cancer Patients.
Saleem M, Ghazali MB, Wahab MAMA, Yusoff NM, Mahsin H, Seng CE, Khalid IA, Rahman MNG, Yahaya BH. Saleem M, et al. Adv Exp Med Biol. 2020;1292:1-12. doi: 10.1007/5584_2018_147. Adv Exp Med Biol. 2020. PMID: 29687286 Review.
Approximately 5-10% of breast cancers are attributable to genetic susceptibility. Mutations in the BRCA1 and BRCA2 genes are the best known genetic factors to date. The goal of this study was to determine the structure and distribution of haplotypes of the BR …
Approximately 5-10% of breast cancers are attributable to genetic susceptibility. Mutations in the BRCA1 and BRCA2 genes …
Comprehensive spectrum of BRCA1 and BRCA2 deleterious mutations in breast cancer in Asian countries.
Kwong A, Shin VY, Ho JC, Kang E, Nakamura S, Teo SH, Lee AS, Sng JH, Ginsburg OM, Kurian AW, Weitzel JN, Siu MT, Law FB, Chan TL, Narod SA, Ford JM, Ma ES, Kim SW. Kwong A, et al. J Med Genet. 2016 Jan;53(1):15-23. doi: 10.1136/jmedgenet-2015-103132. Epub 2015 Jul 17. J Med Genet. 2016. PMID: 26187060 Free PMC article. Review.
Approximately 5%-10% of breast cancers are due to genetic predisposition caused by germline mutations; the most commonly tested genes are BRCA1 and BRCA2 mutations. ...We present the current pathogenic mutation spectrum of BRCA1/BRCA2 genes in p …
Approximately 5%-10% of breast cancers are due to genetic predisposition caused by germline mutations; the most commonly tested ge …
Role of BRCA1 and BRCA2 as regulators of DNA repair, transcription, and cell cycle in response to DNA damage.
Yoshida K, Miki Y. Yoshida K, et al. Cancer Sci. 2004 Nov;95(11):866-71. doi: 10.1111/j.1349-7006.2004.tb02195.x. Cancer Sci. 2004. PMID: 15546503 Free article. Review.
BRCA1 (BReast-CAncer susceptibility gene 1) and BRCA2 are tumor suppressor genes, the mutant phenotypes of which predispose to breast and ovarian cancers. ...The functions of BRCA proteins are also linked to distinct and specific phosphorylation events …
BRCA1 (BReast-CAncer susceptibility gene 1) and BRCA2 are tumor suppressor genes, the mutant phenotypes of which predis …
BRCA2 and pancreatic cancer.
Naderi A, Couch FJ. Naderi A, et al. Int J Gastrointest Cancer. 2002;31(1-3):99-106. doi: 10.1385/IJGC:31:1-3:99. Int J Gastrointest Cancer. 2002. PMID: 12622420 Review.
Patients with pancreatic cancer and germline BRCA2 mutations tend to be Ashkenazi Jewish, have a younger than average age of onset, and in many cases, lack family history for breast, ovarian, or pancreatic cancers. In addition, somatic mutations of BRCA2 …
Patients with pancreatic cancer and germline BRCA2 mutations tend to be Ashkenazi Jewish, have a younger than average age of o …
BRCA2 gene mutation and prostate cancer risk. Comprehensive review and update.
Junejo NN, AlKhateeb SS. Junejo NN, et al. Saudi Med J. 2020 Jan;41(1):9-17. doi: 10.15537/smj.2020.1.24759. Saudi Med J. 2020. PMID: 31915789 Free PMC article. Review.
BRCA1 and BRCA2 mutations have linked with an increased risk for breast, ovarian, and PCa. ...Also, the review summarizes the impact of BRCA2 gene mutation in localized PCa, and the treatment strategies have used for PCa patients with a BRCA2 modification....
BRCA1 and BRCA2 mutations have linked with an increased risk for breast, ovarian, and PCa. ...Also, the review summarizes the impact …
Which Genes for Hereditary Breast Cancer?
Narod SA. Narod SA. N Engl J Med. 2021 Feb 4;384(5):471-473. doi: 10.1056/NEJMe2035083. Epub 2021 Jan 20. N Engl J Med. 2021. PMID: 33471975 No abstract available.
Functions of Breast Cancer Predisposition Genes: Implications for Clinical Management.
Yoshimura A, Imoto I, Iwata H. Yoshimura A, et al. Int J Mol Sci. 2022 Jul 5;23(13):7481. doi: 10.3390/ijms23137481. Int J Mol Sci. 2022. PMID: 35806485 Free PMC article. Review.
Approximately 5-10% of all breast cancer (BC) cases are caused by germline pathogenic variants (GPVs) in various cancer predisposition genes (CPGs). The most common contributors to hereditary BC are BRCA1 and BRCA2, which are associated with hereditary …
Approximately 5-10% of all breast cancer (BC) cases are caused by germline pathogenic variants (GPVs) in various cancer predis …
14,321 results
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