Backman LRF - Search Results

1

New tricks for the glycyl radical enzyme family.

Backman LRF, Funk MA, Dawson CD, Drennan CL. Backman LRF, et al. Crit Rev Biochem Mol Biol. 2017 Dec;52(6):674-695. doi: 10.1080/10409238.2017.1373741. Epub 2017 Sep 13. Crit Rev Biochem Mol Biol. 2017. PMID: 28901199 Free PMC article. Review.

2

Solution structure and biochemical characterization of a spare part protein that restores activity to an oxygen-damaged glycyl radical enzyme.

Bowman SEJ, Backman LRF, Bjork RE, Andorfer MC, Yori S, Caruso A, Stultz CM, Drennan CL. Bowman SEJ, et al. Among authors: backman lrf. J Biol Inorg Chem. 2019 Sep;24(6):817-829. doi: 10.1007/s00775-019-01681-2. Epub 2019 Jun 27. J Biol Inorg Chem. 2019. PMID: 31250200 Free PMC article.

3

Molecular basis for catabolism of the abundant metabolite trans-4-hydroxy-L-proline by a microbial glycyl radical enzyme.

Backman LR, Huang YY, Andorfer MC, Gold B, Raines RT, Balskus EP, Drennan CL. Backman LR, et al. Elife. 2020 Mar 17;9:e51420. doi: 10.7554/eLife.51420. Elife. 2020. PMID: 32180548 Free PMC article.

4

Molecular basis of C-S bond cleavage in the glycyl radical enzyme isethionate sulfite-lyase.

Dawson CD, Irwin SM, Backman LRF, Le C, Wang JX, Vennelakanti V, Yang Z, Kulik HJ, Drennan CL, Balskus EP. Dawson CD, et al. Among authors: backman lrf. Cell Chem Biol. 2021 Sep 16;28(9):1333-1346.e7. doi: 10.1016/j.chembiol.2021.03.001. Epub 2021 Mar 26. Cell Chem Biol. 2021. PMID: 33773110 Free PMC article.

5

Rescuing activity of oxygen-damaged pyruvate formate-lyase by a spare part protein.

Andorfer MC, Backman LRF, Li PL, Ulrich EC, Drennan CL. Andorfer MC, et al. Among authors: backman lrf. J Biol Chem. 2021 Dec;297(6):101423. doi: 10.1016/j.jbc.2021.101423. Epub 2021 Nov 18. J Biol Chem. 2021. PMID: 34801558 Free PMC article.

6

[No title available]

[No authors listed] [No authors listed] PMID: 35553565

7

[No title available]

[No authors listed] [No authors listed] PMID: 35554970

8

The Breast Cancer Tumor Suppressor TRIM29 Is Expressed via ATM-dependent Signaling in Response to Hypoxia.

Dükel M, Streitfeld WS, Tang TC, Backman LR, Ai L, May WS, Brown KD. Dükel M, et al. J Biol Chem. 2016 Oct 7;291(41):21541-21552. doi: 10.1074/jbc.M116.730960. Epub 2016 Aug 17. J Biol Chem. 2016. PMID: 27535224 Free PMC article.

9

Oxidative stress shapes breast cancer phenotype through chronic activation of ATM-dependent signaling.

Alpay M, Backman LR, Cheng X, Dukel M, Kim WJ, Ai L, Brown KD. Alpay M, et al. Breast Cancer Res Treat. 2015 May;151(1):75-87. doi: 10.1007/s10549-015-3368-5. Epub 2015 Apr 11. Breast Cancer Res Treat. 2015. PMID: 25862169

10

ATM is required for SOD2 expression and homeostasis within the mammary gland.

Dyer LM, Kepple JD, Ai L, Kim WJ, Stanton VL, Reinhard MK, Backman LRF, Streitfeld WS, Babu NR, Treiber N, Scharffetter-Kochanek K, McKinnon PJ, Brown KD. Dyer LM, et al. Among authors: backman lrf. Breast Cancer Res Treat. 2017 Dec;166(3):725-741. doi: 10.1007/s10549-017-4424-0. Epub 2017 Aug 28. Breast Cancer Res Treat. 2017. PMID: 28849346 Free PMC article.

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