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Limiting activity at beta1-subunit-containing GABAA receptor subtypes reduces ataxia.
Gee KW, Tran MB, Hogenkamp DJ, Johnstone TB, Bagnera RE, Yoshimura RF, Huang JC, Belluzzi JD, Whittemore ER. Gee KW, et al. Among authors: bagnera re. J Pharmacol Exp Ther. 2010 Mar;332(3):1040-53. doi: 10.1124/jpet.109.161885. Epub 2009 Nov 25. J Pharmacol Exp Ther. 2010. PMID: 19940102 Free PMC article.
Enaminone amides as novel orally active GABAA receptor modulators.
Hogenkamp DJ, Johnstone TB, Huang JC, Li WY, Tran M, Whittemore ER, Bagnera RE, Gee KW. Hogenkamp DJ, et al. Among authors: bagnera re. J Med Chem. 2007 Jul 12;50(14):3369-79. doi: 10.1021/jm070083v. Epub 2007 Jun 16. J Med Chem. 2007. PMID: 17571865