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A white paper on a neurodevelopmental framework for drug discovery in autism and other neurodevelopmental disorders.
Díaz-Caneja CM, State MW, Hagerman RJ, Jacquemont S, Marín O, Bagni C, Umbricht D, Simonoff E, de Andrés-Trelles F, Kaale A, Pandina G, Gómez-Mancilla B, Wang PP, Cusak J, Siafis S, Leucht S, Parellada M, Loth E, Charman T, Buitelaar JK, Murphy D, Arango C. Díaz-Caneja CM, et al. Among authors: bagni c. Eur Neuropsychopharmacol. 2021 Jul;48:49-88. doi: 10.1016/j.euroneuro.2021.02.020. Epub 2021 Mar 27. Eur Neuropsychopharmacol. 2021. PMID: 33781629 Free article. Review.
Protein synthesis levels are increased in a subset of individuals with fragile X syndrome.
Jacquemont S, Pacini L, Jønch AE, Cencelli G, Rozenberg I, He Y, D'Andrea L, Pedini G, Eldeeb M, Willemsen R, Gasparini F, Tassone F, Hagerman R, Gomez-Mancilla B, Bagni C. Jacquemont S, et al. Among authors: bagni c. Hum Mol Genet. 2018 Jun 15;27(12):2039-2051. doi: 10.1093/hmg/ddy099. Hum Mol Genet. 2018. PMID: 29590342 Free PMC article.
Protein synthesis levels are increased in a subset of individuals with fragile X syndrome.
Jacquemont S, Pacini L, Jønch AE, Cencelli G, Rozenberg I, He Y, D'Andrea L, Pedini G, Eldeeb M, Willemsen R, Gasparini F, Tassone F, Hagerman R, Gomez-Mancilla B, Bagni C. Jacquemont S, et al. Among authors: bagni c. Hum Mol Genet. 2018 Nov 1;27(21):3825. doi: 10.1093/hmg/ddy291. Hum Mol Genet. 2018. PMID: 30107584 Free PMC article. No abstract available.
Dysregulated ADAM10-Mediated Processing of APP during a Critical Time Window Leads to Synaptic Deficits in Fragile X Syndrome.
Pasciuto E, Ahmed T, Wahle T, Gardoni F, D'Andrea L, Pacini L, Jacquemont S, Tassone F, Balschun D, Dotti CG, Callaerts-Vegh Z, D'Hooge R, Müller UC, Di Luca M, De Strooper B, Bagni C. Pasciuto E, et al. Among authors: bagni c. Neuron. 2015 Jul 15;87(2):382-98. doi: 10.1016/j.neuron.2015.06.032. Neuron. 2015. PMID: 26182420 Free article.
Autism Spectrum Disorders: Translating human deficits into mouse behavior.
Pasciuto E, Borrie SC, Kanellopoulos AK, Santos AR, Cappuyns E, D'Andrea L, Pacini L, Bagni C. Pasciuto E, et al. Among authors: bagni c. Neurobiol Learn Mem. 2015 Oct;124:71-87. doi: 10.1016/j.nlm.2015.07.013. Epub 2015 Jul 26. Neurobiol Learn Mem. 2015. PMID: 26220900 Review.
Maintenance mechanisms of circuit-integrated axons.
Mariano V, Domínguez-Iturza N, Neukomm LJ, Bagni C. Mariano V, et al. Among authors: bagni c. Curr Opin Neurobiol. 2018 Dec;53:162-173. doi: 10.1016/j.conb.2018.08.007. Epub 2018 Sep 18. Curr Opin Neurobiol. 2018. PMID: 30241058 Review.
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