Baker BF - Search Results

1

IONIS-PKK_Rx a Novel Antisense Inhibitor of Prekallikrein and Bradykinin Production.

Ferrone JD, Bhattacharjee G, Revenko AS, Zanardi TA, Warren MS, Derosier FJ, Viney NJ, Pham NC, Kaeser GE, Baker BF, Schneider E, Hughes SG, Monia BP, MacLeod AR. Ferrone JD, et al. Among authors: baker bf. Nucleic Acid Ther. 2019 Apr;29(2):82-91. doi: 10.1089/nat.2018.0754. Epub 2019 Feb 28. Nucleic Acid Ther. 2019. PMID: 30817230 Free PMC article.

2

Novel mechanisms for antisense-mediated regulation of gene expression.

Baker BF, Monia BP. Baker BF, et al. Biochim Biophys Acta. 1999 Dec 10;1489(1):3-18. doi: 10.1016/s0167-4781(99)00146-3. Biochim Biophys Acta. 1999. PMID: 10806993 Review. No abstract available.

3

Discovery and analysis of antisense oligonucleotide activity in cell culture.

Baker BF, Condon TP, Koller E, McKay RA, Siwkowski AM, Vickers TA, Monia BP. Baker BF, et al. Methods. 2001 Feb;23(2):191-8. doi: 10.1006/meth.2000.1120. Methods. 2001. PMID: 11181038 Review.

4

Effects of antisense oligonucleotide-mediated depletion of tumor necrosis factor (TNF) receptor 1-associated death domain protein on TNF-induced gene expression.

Siwkowski AM, Madge LA, Koo S, McMillan EL, Monia BP, Pober JS, Baker BF. Siwkowski AM, et al. Among authors: baker bf. Mol Pharmacol. 2004 Sep;66(3):572-9. doi: 10.1124/mol.66.3.. Mol Pharmacol. 2004. PMID: 15322249

5

Targeting APOC3 in the familial chylomicronemia syndrome.

Gaudet D, Brisson D, Tremblay K, Alexander VJ, Singleton W, Hughes SG, Geary RS, Baker BF, Graham MJ, Crooke RM, Witztum JL. Gaudet D, et al. Among authors: baker bf. N Engl J Med. 2014 Dec 4;371(23):2200-6. doi: 10.1056/NEJMoa1400284. N Engl J Med. 2014. PMID: 25470695 Free article.

6

Antisense therapy targeting apolipoprotein(a): a randomised, double-blind, placebo-controlled phase 1 study.

Tsimikas S, Viney NJ, Hughes SG, Singleton W, Graham MJ, Baker BF, Burkey JL, Yang Q, Marcovina SM, Geary RS, Crooke RM, Witztum JL. Tsimikas S, et al. Among authors: baker bf. Lancet. 2015 Oct 10;386(10002):1472-83. doi: 10.1016/S0140-6736(15)61252-1. Epub 2015 Jul 22. Lancet. 2015. PMID: 26210642 Clinical Trial.

7

Antisense Inhibition of Apolipoprotein C-III in Patients with Hypertriglyceridemia.

Gaudet D, Alexander VJ, Baker BF, Brisson D, Tremblay K, Singleton W, Geary RS, Hughes SG, Viney NJ, Graham MJ, Crooke RM, Witztum JL, Brunzell JD, Kastelein JJ. Gaudet D, et al. Among authors: baker bf. N Engl J Med. 2015 Jul 30;373(5):438-47. doi: 10.1056/NEJMoa1400283. N Engl J Med. 2015. PMID: 26222559 Free article. Clinical Trial.

8

Antisense-Mediated Lowering of Plasma Apolipoprotein C-III by Volanesorsen Improves Dyslipidemia and Insulin Sensitivity in Type 2 Diabetes.

Digenio A, Dunbar RL, Alexander VJ, Hompesch M, Morrow L, Lee RG, Graham MJ, Hughes SG, Yu R, Singleton W, Baker BF, Bhanot S, Crooke RM. Digenio A, et al. Among authors: baker bf. Diabetes Care. 2016 Aug;39(8):1408-15. doi: 10.2337/dc16-0126. Epub 2016 Jun 6. Diabetes Care. 2016. PMID: 27271183 Clinical Trial.

9

Integrated Safety Assessment of 2'-O-Methoxyethyl Chimeric Antisense Oligonucleotides in NonHuman Primates and Healthy Human Volunteers.

Crooke ST, Baker BF, Kwoh TJ, Cheng W, Schulz DJ, Xia S, Salgado N, Bui HH, Hart CE, Burel SA, Younis HS, Geary RS, Henry SP, Bhanot S. Crooke ST, et al. Among authors: baker bf. Mol Ther. 2016 Oct;24(10):1771-1782. doi: 10.1038/mt.2016.136. Epub 2016 Jun 30. Mol Ther. 2016. PMID: 27357629 Free PMC article.

10

Pharmacology of Antisense Drugs.

Bennett CF, Baker BF, Pham N, Swayze E, Geary RS. Bennett CF, et al. Among authors: baker bf. Annu Rev Pharmacol Toxicol. 2017 Jan 6;57:81-105. doi: 10.1146/annurev-pharmtox-010716-104846. Epub 2016 Oct 10. Annu Rev Pharmacol Toxicol. 2017. PMID: 27732800 Review.

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