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A covalent fragment-based strategy targeting a novel cysteine to inhibit activity of mutant EGFR kinase.
Kuki N, Walmsley DL, Kanai K, Takechi S, Yoshida M, Murakami R, Takano K, Tominaga Y, Takahashi M, Ito S, Nakao N, Angove H, Baker LM, Carter E, Dokurno P, Le Strat L, Macias AT, Molyneaux CA, Murray JB, Surgenor AE, Hamada T, Hubbard RE. Kuki N, et al. Among authors: baker lm. RSC Med Chem. 2023 Oct 19;14(12):2731-2737. doi: 10.1039/d3md00439b. eCollection 2023 Dec 13. RSC Med Chem. 2023. PMID: 38107172
PAC-FragmentDEL - photoactivated covalent capture of DNA-encoded fragments for hit discovery.
Ma H, Murray JB, Luo H, Cheng X, Chen Q, Song C, Duan C, Tan P, Zhang L, Liu J, Morgan BA, Li J, Wan J, Baker LM, Finnie W, Guetzoyan L, Harris R, Hendrickson N, Matassova N, Simmonite H, Smith J, Hubbard RE, Liu G. Ma H, et al. Among authors: baker lm. RSC Med Chem. 2022 Aug 26;13(11):1341-1349. doi: 10.1039/d2md00197g. eCollection 2022 Nov 16. RSC Med Chem. 2022. PMID: 36426238 Free PMC article.
The Impact of Lab4 Probiotic Supplementation in a 90-Day Study in Wistar Rats.
Webberley TS, Masetti G, Baker LM, Dally J, Hughes TR, Marchesi JR, Jack AA, Plummer SF, Ramanathan G, Facey PD, Michael DR. Webberley TS, et al. Among authors: baker lm. Front Nutr. 2021 Nov 25;8:778289. doi: 10.3389/fnut.2021.778289. eCollection 2021. Front Nutr. 2021. PMID: 34901123 Free PMC article.
A genome guided evaluation of the Lab4 probiotic consortium.
Baker LM, Webberley TS, Masetti G, Hughes TR, Marchesi JR, Jack AA, Joyce TSC, Allen MD, Plummer SF, Michael DR, Ramanathan G, Del Sol R, Facey PD. Baker LM, et al. Genomics. 2021 Nov;113(6):4028-4038. doi: 10.1016/j.ygeno.2021.08.007. Epub 2021 Aug 13. Genomics. 2021. PMID: 34391865 Free article.
79 results