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Systems Toxicology of Male Reproductive Development: Profiling 774 Chemicals for Molecular Targets and Adverse Outcomes.
Leung MC, Phuong J, Baker NC, Sipes NS, Klinefelter GR, Martin MT, McLaurin KW, Setzer RW, Darney SP, Judson RS, Knudsen TB. Leung MC, et al. Among authors: baker nc. Environ Health Perspect. 2016 Jul;124(7):1050-61. doi: 10.1289/ehp.1510385. Epub 2015 Dec 11. Environ Health Perspect. 2016. PMID: 26662846 Free PMC article.
We confirmed the known role of estrogen and androgen signaling pathways in rodent TDS, and importantly, broadened the list of molecular targets to include retinoic acid signaling, vascular remodeling proteins, G-protein coupled receptors (GPCRs), and cytochrome P450s. CITATION: L …
We confirmed the known role of estrogen and androgen signaling pathways in rodent TDS, and importantly, broadened the list of molecular targ …
Building a developmental toxicity ontology.
Baker N, Boobis A, Burgoon L, Carney E, Currie R, Fritsche E, Knudsen T, Laffont M, Piersma AH, Poole A, Schneider S, Daston G. Baker N, et al. Birth Defects Res. 2018 Apr 3;110(6):502-518. doi: 10.1002/bdr2.1189. Epub 2018 Jan 31. Birth Defects Res. 2018. PMID: 29383852 Review.
Evaluation of androgen assay results using a curated Hershberger database.
Kleinstreuer NC, Browne P, Chang X, Judson R, Casey W, Ceger P, Deisenroth C, Baker N, Markey K, Thomas RS. Kleinstreuer NC, et al. Among authors: baker n. Reprod Toxicol. 2018 Oct;81:272-280. doi: 10.1016/j.reprotox.2018.08.017. Epub 2018 Sep 8. Reprod Toxicol. 2018. PMID: 30205137 Free PMC article.
Systems Modeling of Developmental Vascular Toxicity.
Saili KS, Franzosa JA, Baker NC, Ellis-Hutchings RG, Settivari RS, Carney EW, Spencer R, Zurlinden TJ, Kleinstreuer NC, Li S, Xia M, Knudsen TB. Saili KS, et al. Among authors: baker nc. Curr Opin Toxicol. 2019 Jun 1;15(1):55-63. doi: 10.1016/j.cotox.2019.04.004. Curr Opin Toxicol. 2019. PMID: 32030360 Free PMC article.
93 results