Bakker ML - Search Results

1

Lethal arrhythmias in Tbx3-deficient mice reveal extreme dosage sensitivity of cardiac conduction system function and homeostasis.

Frank DU, Carter KL, Thomas KR, Burr RM, Bakker ML, Coetzee WA, Tristani-Firouzi M, Bamshad MJ, Christoffels VM, Moon AM. Frank DU, et al. Among authors: bakker ml. Proc Natl Acad Sci U S A. 2012 Jan 17;109(3):E154-63. doi: 10.1073/pnas.1115165109. Epub 2011 Dec 27. Proc Natl Acad Sci U S A. 2012. PMID: 22203979 Free PMC article.

2

The cardiac pacemaker and conduction system develops from embryonic myocardium that retains its primitive phenotype.

Bakker ML, Christoffels VM, Moorman AF. Bakker ML, et al. J Cardiovasc Pharmacol. 2010 Jul;56(1):6-15. doi: 10.1097/FJC.0b013e3181e775d3. J Cardiovasc Pharmacol. 2010. PMID: 20505520 Review.

3

Transcription factor Tbx3 is required for the specification of the atrioventricular conduction system.

Bakker ML, Boukens BJ, Mommersteeg MT, Brons JF, Wakker V, Moorman AF, Christoffels VM. Bakker ML, et al. Circ Res. 2008 Jun 6;102(11):1340-9. doi: 10.1161/CIRCRESAHA.107.169565. Epub 2008 May 8. Circ Res. 2008. PMID: 18467625

4

The atrioventricular node: origin, development, and genetic program.

Bakker ML, Moorman AF, Christoffels VM. Bakker ML, et al. Trends Cardiovasc Med. 2010 Jul;20(5):164-71. doi: 10.1016/j.tcm.2011.02.001. Trends Cardiovasc Med. 2010. PMID: 21742272 Review.

5

Gene expression profiling of the forming atrioventricular node using a novel tbx3-based node-specific transgenic reporter.

Horsthuis T, Buermans HP, Brons JF, Verkerk AO, Bakker ML, Wakker V, Clout DE, Moorman AF, 't Hoen PA, Christoffels VM. Horsthuis T, et al. Among authors: bakker ml. Circ Res. 2009 Jul 2;105(1):61-9. doi: 10.1161/CIRCRESAHA.108.192443. Epub 2009 Jun 4. Circ Res. 2009. PMID: 19498200

6

T-box transcription factor TBX3 reprogrammes mature cardiac myocytes into pacemaker-like cells.

Bakker ML, Boink GJ, Boukens BJ, Verkerk AO, van den Boogaard M, den Haan AD, Hoogaars WM, Buermans HP, de Bakker JM, Seppen J, Tan HL, Moorman AF, 't Hoen PA, Christoffels VM. Bakker ML, et al. Cardiovasc Res. 2012 Jun 1;94(3):439-49. doi: 10.1093/cvr/cvs120. Epub 2012 Mar 14. Cardiovasc Res. 2012. PMID: 22419669

7

Tbx3 controls the sinoatrial node gene program and imposes pacemaker function on the atria.

Hoogaars WM, Engel A, Brons JF, Verkerk AO, de Lange FJ, Wong LY, Bakker ML, Clout DE, Wakker V, Barnett P, Ravesloot JH, Moorman AF, Verheijck EE, Christoffels VM. Hoogaars WM, et al. Among authors: bakker ml. Genes Dev. 2007 May 1;21(9):1098-112. doi: 10.1101/gad.416007. Genes Dev. 2007. PMID: 17473172 Free PMC article.

8

Sox4 mediates Tbx3 transcriptional regulation of the gap junction protein Cx43.

Boogerd CJ, Wong LY, van den Boogaard M, Bakker ML, Tessadori F, Bakkers J, 't Hoen PA, Moorman AF, Christoffels VM, Barnett P. Boogerd CJ, et al. Among authors: bakker ml. Cell Mol Life Sci. 2011 Dec;68(23):3949-61. doi: 10.1007/s00018-011-0693-7. Epub 2011 May 3. Cell Mol Life Sci. 2011. PMID: 21538160 Free PMC article.

9

Genetic variation in T-box binding element functionally affects SCN5A/SCN10A enhancer.

van den Boogaard M, Wong LY, Tessadori F, Bakker ML, Dreizehnter LK, Wakker V, Bezzina CR, 't Hoen PA, Bakkers J, Barnett P, Christoffels VM. van den Boogaard M, et al. Among authors: bakker ml. J Clin Invest. 2012 Jul;122(7):2519-30. doi: 10.1172/JCI62613. Epub 2012 Jun 18. J Clin Invest. 2012. PMID: 22706305 Free PMC article.

10

Transcriptional repressor Tbx3 is required for the hormone-sensing cell lineage in mammary epithelium.

Kunasegaran K, Ho V, Chang TH, De Silva D, Bakker ML, Christoffels VM, Pietersen AM. Kunasegaran K, et al. Among authors: bakker ml. PLoS One. 2014 Oct 24;9(10):e110191. doi: 10.1371/journal.pone.0110191. eCollection 2014. PLoS One. 2014. PMID: 25343378 Free PMC article.

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