Balzarini J - Search Results

1

A two plasmid co-expression system in Escherichia coli for the production of virion-like reverse transcriptase of the human immunodeficiency virus type 1.

Jonckheere H, De Vreese K, Debyser Z, Vandekerckhove J, Balzarini J, Desmyter J, De Clercq E, Anné J. Jonckheere H, et al. Among authors: balzarini j. J Virol Methods. 1996 Sep;61(1-2):113-25. doi: 10.1016/0166-0934(96)02076-9. J Virol Methods. 1996. PMID: 8882944

2

Resistance of HIV-1 reverse transcriptase against [2',5'-bis-O-(tert-butyldimethylsilyl)-3'-spiro-5''-(4''-amino-1'',2''- oxathiole-2'',2''-dioxide)] (TSAO) derivatives is determined by the mutation Glu138-->Lys on the p51 subunit.

Jonckheere H, Taymans JM, Balzarini J, Velázquez S, Camarasa MJ, Desmyter J, De Clercq E, Anné J. Jonckheere H, et al. Among authors: balzarini j. J Biol Chem. 1994 Oct 14;269(41):25255-8. J Biol Chem. 1994. PMID: 7523383 Free article.

3

Differential activities of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine derivatives against different human immunodeficiency virus type 1 mutant strains.

Balzarini J, Baba M, De Clercq E. Balzarini J, et al. Antimicrob Agents Chemother. 1995 Apr;39(4):998-1002. doi: 10.1128/AAC.39.4.998. Antimicrob Agents Chemother. 1995. PMID: 7540384 Free PMC article.

4

Knocking out human immunodeficiency virus through non-nucleoside reverse transcriptase inhibitors used as single agents or in combinations: a paradigm for the cure of AIDS?

De Clercq E, Balzarini J. De Clercq E, et al. Among authors: balzarini j. Farmaco. 1995 Nov;50(11):735-47. Farmaco. 1995. PMID: 8593170 Review.

5

Analysis of inhibition of retroviral reverse transcriptase.

Balzarini J, De Clercq E. Balzarini J, et al. Methods Enzymol. 1996;275:472-502. doi: 10.1016/s0076-6879(96)75027-9. Methods Enzymol. 1996. PMID: 9026655 Review. No abstract available.

6

SIV/HIV-1 hybrid virus expressing the reverse transcriptase gene of HIV-1 remains sensitive to HIV-1-specific reverse transcriptase inhibitors after passage in rhesus macaques.

Balzarini J, De Clercq E, Uberla K. Balzarini J, et al. J Acquir Immune Defic Syndr Hum Retrovirol. 1997 May 1;15(1):1-4. doi: 10.1097/00042560-199705010-00001. J Acquir Immune Defic Syndr Hum Retrovirol. 1997. PMID: 9215647

7

1,1,3-Trioxo-2H,4H-thieno[3,4-e][1,2,4]thiadiazine (TTD) derivatives: a new class of nonnucleoside human immunodeficiency virus type 1 (HIV-1) reverse transcriptase inhibitors with anti-HIV-1 activity.

Witvrouw M, Arranz ME, Pannecouque C, Declercq R, Jonckheere H, Schmit JC, Vandamme AM, Diaz JA, Ingate ST, Desmyter J, Esnouf R, Van Meervelt L, Vega S, Balzarini J, De Clercq E. Witvrouw M, et al. Among authors: balzarini j. Antimicrob Agents Chemother. 1998 Mar;42(3):618-23. doi: 10.1128/AAC.42.3.618. Antimicrob Agents Chemother. 1998. PMID: 9517942 Free PMC article.

8

Mutational analysis of Tyr-318 within the non-nucleoside reverse transcriptase inhibitor binding pocket of human immunodeficiency virus type I reverse transcriptase.

Pelemans H, Esnouf RM, Jonckheere H, De Clercq E, Balzarini J. Pelemans H, et al. Among authors: balzarini j. J Biol Chem. 1998 Dec 18;273(51):34234-9. doi: 10.1074/jbc.273.51.34234. J Biol Chem. 1998. PMID: 9852086 Free article.

9

Chimeric human immunodeficiency virus type 1 and feline immunodeficiency virus reverse transcriptases: role of the subunits in resistance/sensitivity to non-nucleoside reverse transcriptase inhibitors.

Auwerx J, North TW, Preston BD, Klarmann GJ, De Clercq E, Balzarini J. Auwerx J, et al. Among authors: balzarini j. Mol Pharmacol. 2002 Feb;61(2):400-6. doi: 10.1124/mol.61.2.400. Mol Pharmacol. 2002. PMID: 11809865

10

N-aminoimidazole derivatives inhibiting retroviral replication via a yet unidentified mode of action.

Lagoja IM, Pannecouque C, Van Aerschot A, Witvrouw M, Debyser Z, Balzarini J, Herdewijn P, De Clercq E. Lagoja IM, et al. Among authors: balzarini j. J Med Chem. 2003 Apr 10;46(8):1546-53. doi: 10.1021/jm0211117. J Med Chem. 2003. PMID: 12672256

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