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N,N-Dimethyl-[9-(arylsulfonyl)-2,3,4,9-tetrahydro-1H-carbazol-3-yl]amines as novel, potent and selective 5-HT₆ receptor antagonists.
Bioorg Med Chem Lett. 2012 Nov 15;22(22):6980-5. doi: 10.1016/j.bmcl.2012.06.002. Epub 2012 Aug 30.
Bioorg Med Chem Lett. 2012.
PMID: 23036955
Synthesis and structure-activity relationship of novel conformationally restricted analogues of serotonin as 5-HT6 receptor ligands.
Nirogi RV, Kambhampati R, Kothmirkar P, Konda J, Bandyala TR, Gudla P, Arepalli S, Gangadasari NP, Shinde AK, Deshpande AD, Dwarampudi A, Chindhe AK, Dubey PK.
Nirogi RV, et al. Among authors: bandyala tr.
J Enzyme Inhib Med Chem. 2012 Jun;27(3):443-50. doi: 10.3109/14756366.2011.595713. Epub 2011 Jul 21.
J Enzyme Inhib Med Chem. 2012.
PMID: 21774748
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Design, synthesis and pharmacological evaluation of indolylsulfonamide amines as potent and selective 5-HT6 receptor antagonists.
Nirogi RV, Bandyala TR, Reballi V, Konda JB, Daulatabad AV, Khagga M.
Nirogi RV, et al. Among authors: bandyala tr.
J Enzyme Inhib Med Chem. 2015 Feb;30(1):85-97. doi: 10.3109/14756366.2014.889126. Epub 2014 Mar 25.
J Enzyme Inhib Med Chem. 2015.
PMID: 24666297
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Synthesis and biological evaluation of novel N1-phenylsulphonyl indole derivatives as potent and selective 5-HT6R ligands for the treatment of cognitive disorders.
Nirogi RV, Bandyala TR, Gangadasari PR, Khagga M.
Nirogi RV, et al. Among authors: bandyala tr.
J Enzyme Inhib Med Chem. 2016;31(sup1):1-15. doi: 10.3109/14756366.2015.1103233. Epub 2016 Nov 3.
J Enzyme Inhib Med Chem. 2016.
PMID: 27806648
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Discovery and Development of 1-[(2-Bromophenyl)sulfonyl]-5-methoxy-3-[(4-methyl-1-piperazinyl)methyl]-1H-indole Dimesylate Monohydrate (SUVN-502): A Novel, Potent, Selective and Orally Active Serotonin 6 (5-HT6) Receptor Antagonist for Potential Treatment of Alzheimer's Disease.
Nirogi R, Shinde A, Kambhampati RS, Mohammed AR, Saraf SK, Badange RK, Bandyala TR, Bhatta V, Bojja K, Reballi V, Subramanian R, Benade V, Palacharla RC, Bhyrapuneni G, Jayarajan P, Goyal V, Jasti V.
Nirogi R, et al. Among authors: bandyala tr.
J Med Chem. 2017 Mar 9;60(5):1843-1859. doi: 10.1021/acs.jmedchem.6b01662. Epub 2017 Feb 17.
J Med Chem. 2017.
PMID: 28212021
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Discovery and Development of N-[4-(1-Cyclobutylpiperidin-4-yloxy)phenyl]-2-(morpholin-4-yl)acetamide Dihydrochloride (SUVN-G3031): A Novel, Potent, Selective, and Orally Active Histamine H3 Receptor Inverse Agonist with Robust Wake-Promoting Activity.
Nirogi R, Shinde A, Mohammed AR, Badange RK, Reballi V, Bandyala TR, Saraf SK, Bojja K, Manchineella S, Achanta PK, Kandukuri KK, Subramanian R, Benade V, Palacharla RC, Jayarajan P, Pandey S, Jasti V.
Nirogi R, et al. Among authors: bandyala tr.
J Med Chem. 2019 Feb 14;62(3):1203-1217. doi: 10.1021/acs.jmedchem.8b01280. Epub 2019 Jan 25.
J Med Chem. 2019.
PMID: 30629436
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