Barker MD - Search Results

1

Kinetic resolution of racemic pyrrolidine-2,5-diones using chiral oxazaborolidine catalysts.

Barker MD, Dixon RA, Jones S, Marsh BJ. Barker MD, et al. Chem Commun (Camb). 2008 May 21;(19):2218-20. doi: 10.1039/b800510a. Epub 2008 Mar 11. Chem Commun (Camb). 2008. PMID: 18463745

2

Enantioselective catalytic desymmetrization of maleimides by temporary removal of an internal mirror plane and stereoablative over-reduction: synthesis of (R)-pyrrolam A.

Marsh BJ, Adams H, Barker MD, Kutama IU, Jones S. Marsh BJ, et al. Among authors: barker md. Org Lett. 2014 Jul 18;16(14):3780-3. doi: 10.1021/ol5016702. Epub 2014 Jun 27. Org Lett. 2014. PMID: 24972082 Free article.

3

Carbon-carbon bond forming reactions with substrates absorbed non-covalently on a cellulose chromatography paper support.

Hacon J, Morris A, Johnston MJ, Shanahan SE, Barker MD, Inglis GG, Macdonald SJ. Hacon J, et al. Among authors: barker md. Chem Commun (Camb). 2007 Feb 14;(6):625-7. doi: 10.1039/b611824k. Epub 2006 Nov 6. Chem Commun (Camb). 2007. PMID: 17264912

4

Dissociated nonsteroidal glucocorticoid receptor modulators; discovery of the agonist trigger in a tetrahydronaphthalene-benzoxazine series.

Barker M, Clackers M, Copley R, Demaine DA, Humphreys D, Inglis GG, Johnston MJ, Jones HT, Haase MV, House D, Loiseau R, Nisbet L, Pacquet F, Skone PA, Shanahan SE, Tape D, Vinader VM, Washington M, Uings I, Upton R, McLay IM, Macdonald SJ. Barker M, et al. J Med Chem. 2006 Jul 13;49(14):4216-31. doi: 10.1021/jm060302x. J Med Chem. 2006. PMID: 16821781

5

Design and synthesis of new nonsteroidal glucocorticoid modulators through application of an "agreement docking" method.

Barker M, Clackers M, Demaine DA, Humphreys D, Johnston MJ, Jones HT, Pacquet F, Pritchard JM, Salter M, Shanahan SE, Skone PA, Vinader VM, Uings I, McLay IM, Macdonald SJ. Barker M, et al. J Med Chem. 2005 Jul 14;48(14):4507-10. doi: 10.1021/jm050345y. J Med Chem. 2005. PMID: 15999989

6

4-Phenyl-7-azaindoles as potent and selective IKK2 inhibitors.

Liddle J, Bamborough P, Barker MD, Campos S, Cousins RP, Cutler GJ, Hobbs H, Holmes DS, Ioannou C, Mellor GW, Morse MA, Payne JJ, Pritchard JM, Smith KJ, Tape DT, Whitworth C, Williamson RA. Liddle J, et al. Among authors: barker md. Bioorg Med Chem Lett. 2009 May 1;19(9):2504-8. doi: 10.1016/j.bmcl.2009.03.034. Epub 2009 Mar 14. Bioorg Med Chem Lett. 2009. PMID: 19349179

7

Palladium-catalyzed [1,3]-O-to-C rearrangement of pyrans toward functionalized cyclohexanones.

Brioche JC, Barker TA, Whatrup DJ, Barker MD, Harrity JP. Brioche JC, et al. Among authors: barker md, barker ta. Org Lett. 2010 Nov 5;12(21):4832-5. doi: 10.1021/ol102213s. Org Lett. 2010. PMID: 20886864

8

A Turing Test for Molecular Generators.

Bush JT, Pogany P, Pickett SD, Barker M, Baxter A, Campos S, Cooper AWJ, Hirst D, Inglis G, Nadin A, Patel VK, Poole D, Pritchard J, Washio Y, White G, Green DVS. Bush JT, et al. J Med Chem. 2020 Oct 22;63(20):11964-11971. doi: 10.1021/acs.jmedchem.0c01148. Epub 2020 Oct 12. J Med Chem. 2020. PMID: 32955254

9

The synthesis of an EDTA-like chelating peptidomimetic building block suitable for solid-phase peptide synthesis.

Spengler J, Barker M, Schelhorn C, García J, Macias MJ, Albericio F. Spengler J, et al. Chem Commun (Camb). 2017 Feb 23;53(17):2634-2636. doi: 10.1039/c6cc10203d. Chem Commun (Camb). 2017. PMID: 28198898

10

4-Phenyl-7-azaindoles as potent, selective and bioavailable IKK2 inhibitors demonstrating good in vivo efficacy.

Liddle J, Bamborough P, Barker MD, Campos S, Chung CW, Cousins RP, Faulder P, Heathcote ML, Hobbs H, Holmes DS, Ioannou C, Ramirez-Molina C, Morse MA, Osborn R, Payne JJ, Pritchard JM, Rumsey WL, Tape DT, Vicentini G, Whitworth C, Williamson RA. Liddle J, et al. Among authors: barker md. Bioorg Med Chem Lett. 2012 Aug 15;22(16):5222-6. doi: 10.1016/j.bmcl.2012.06.065. Epub 2012 Jun 26. Bioorg Med Chem Lett. 2012. PMID: 22801646

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